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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALO17
Full Name:
Protein ALO17
Alias:
ALK lymphoma oligomerization partner on chromosome 17; KIAA1618
Type:
Oncoprotein
Mass (Da):
174897
Number AA:
1550
UniProt ID:
Q9HCF4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
C
P
S
C
Q
H
V
S
K
E
E
T
P
K
F
Site 2
T14
Q
H
V
S
K
E
E
T
P
K
F
C
S
Q
C
Site 3
S19
E
E
T
P
K
F
C
S
Q
C
G
E
R
L
P
Site 4
S34
P
A
A
P
I
A
D
S
E
N
N
N
S
T
M
Site 5
S39
A
D
S
E
N
N
N
S
T
M
A
S
A
S
E
Site 6
S43
N
N
N
S
T
M
A
S
A
S
E
G
E
M
E
Site 7
S45
N
S
T
M
A
S
A
S
E
G
E
M
E
C
G
Site 8
S67
G
P
C
L
F
P
G
S
D
S
W
Q
E
N
P
Site 9
S69
C
L
F
P
G
S
D
S
W
Q
E
N
P
E
E
Site 10
S79
E
N
P
E
E
P
C
S
K
A
S
W
T
V
Q
Site 11
S82
E
E
P
C
S
K
A
S
W
T
V
Q
E
S
K
Site 12
T84
P
C
S
K
A
S
W
T
V
Q
E
S
K
K
K
Site 13
S102
K
K
K
K
G
N
K
S
A
S
S
E
L
A
S
Site 14
S104
K
K
G
N
K
S
A
S
S
E
L
A
S
L
P
Site 15
S105
K
G
N
K
S
A
S
S
E
L
A
S
L
P
L
Site 16
S109
S
A
S
S
E
L
A
S
L
P
L
S
P
A
S
Site 17
T121
P
A
S
P
C
H
L
T
L
L
S
N
P
W
P
Site 18
T131
S
N
P
W
P
Q
D
T
A
L
P
H
S
Q
A
Site 19
S136
Q
D
T
A
L
P
H
S
Q
A
Q
Q
S
G
P
Site 20
S141
P
H
S
Q
A
Q
Q
S
G
P
T
G
Q
P
S
Site 21
S148
S
G
P
T
G
Q
P
S
Q
P
P
G
T
A
T
Site 22
T156
Q
P
P
G
T
A
T
T
P
L
E
G
D
G
L
Site 23
S164
P
L
E
G
D
G
L
S
A
P
T
E
V
G
D
Site 24
S172
A
P
T
E
V
G
D
S
P
L
Q
A
Q
A
L
Site 25
S188
E
A
G
V
A
T
G
S
E
A
Q
S
S
P
Q
Site 26
S192
A
T
G
S
E
A
Q
S
S
P
Q
F
Q
D
H
Site 27
S193
T
G
S
E
A
Q
S
S
P
Q
F
Q
D
H
T
Site 28
T200
S
P
Q
F
Q
D
H
T
E
G
E
D
Q
D
A
Site 29
S208
E
G
E
D
Q
D
A
S
I
P
S
G
G
R
G
Site 30
S211
D
Q
D
A
S
I
P
S
G
G
R
G
L
S
Q
Site 31
S217
P
S
G
G
R
G
L
S
Q
E
G
T
G
P
P
Site 32
T221
R
G
L
S
Q
E
G
T
G
P
P
T
S
A
G
Site 33
T225
Q
E
G
T
G
P
P
T
S
A
G
E
G
H
S
Site 34
S226
E
G
T
G
P
P
T
S
A
G
E
G
H
S
R
Site 35
S246
Q
E
L
L
L
P
E
S
K
G
G
S
S
E
P
Site 36
S250
L
P
E
S
K
G
G
S
S
E
P
G
T
E
L
Site 37
S251
P
E
S
K
G
G
S
S
E
P
G
T
E
L
Q
Site 38
T255
G
G
S
S
E
P
G
T
E
L
Q
T
T
E
Q
Site 39
T260
P
G
T
E
L
Q
T
T
E
Q
Q
A
G
A
S
Site 40
T293
G
K
E
M
K
E
K
T
Q
R
M
K
Q
P
P
Site 41
T302
R
M
K
Q
P
P
A
T
T
P
P
F
K
T
H
Site 42
T303
M
K
Q
P
P
A
T
T
P
P
F
K
T
H
C
Site 43
S371
D
V
Q
E
V
K
A
S
T
L
S
P
G
G
G
Site 44
Y422
S
N
I
C
E
L
H
Y
T
R
D
L
G
H
D
Site 45
Y447
S
K
K
H
L
D
K
Y
I
P
Y
K
Y
V
I
Site 46
Y450
H
L
D
K
Y
I
P
Y
K
Y
V
I
Y
N
G
Site 47
Y452
D
K
Y
I
P
Y
K
Y
V
I
Y
N
G
E
S
Site 48
Y455
I
P
Y
K
Y
V
I
Y
N
G
E
S
F
E
Y
Site 49
Y462
Y
N
G
E
S
F
E
Y
E
F
I
Y
K
H
Q
Site 50
Y466
S
F
E
Y
E
F
I
Y
K
H
Q
Q
K
K
G
Site 51
Y475
H
Q
Q
K
K
G
E
Y
V
N
R
C
L
F
I
Site 52
S484
N
R
C
L
F
I
K
S
S
L
L
G
S
G
D
Site 53
S489
I
K
S
S
L
L
G
S
G
D
W
H
Q
Y
Y
Site 54
Y495
G
S
G
D
W
H
Q
Y
Y
D
I
V
Y
M
K
Site 55
Y500
H
Q
Y
Y
D
I
V
Y
M
K
P
H
G
R
L
Site 56
T515
Q
K
V
M
N
H
I
T
D
G
P
R
K
D
L
Site 57
T543
S
T
F
S
I
L
Q
T
W
D
T
I
N
L
N
Site 58
Y581
Q
L
W
T
D
L
Q
Y
R
E
K
E
V
K
R
Site 59
Y589
R
E
K
E
V
K
R
Y
L
W
Q
H
L
K
K
Site 60
S606
V
P
L
P
D
G
K
S
T
D
F
L
P
V
D
Site 61
T649
D
W
L
C
H
L
L
T
S
D
A
S
S
P
D
Site 62
S650
W
L
C
H
L
L
T
S
D
A
S
S
P
D
E
Site 63
S653
H
L
L
T
S
D
A
S
S
P
D
E
F
H
R
Site 64
S654
L
L
T
S
D
A
S
S
P
D
E
F
H
R
D
Site 65
S663
D
E
F
H
R
D
L
S
H
I
L
G
I
P
Q
Site 66
Y675
I
P
Q
S
W
R
L
Y
L
V
N
L
C
Q
R
Site 67
Y689
R
C
M
D
T
R
T
Y
T
W
L
G
A
L
P
Site 68
T718
A
W
R
Q
P
E
D
T
W
A
A
L
E
G
L
Site 69
S726
W
A
A
L
E
G
L
S
F
S
P
F
R
E
Q
Site 70
S728
A
L
E
G
L
S
F
S
P
F
R
E
Q
M
L
Site 71
T737
F
R
E
Q
M
L
D
T
S
S
L
L
Q
F
M
Site 72
S738
R
E
Q
M
L
D
T
S
S
L
L
Q
F
M
R
Site 73
S739
E
Q
M
L
D
T
S
S
L
L
Q
F
M
R
E
Site 74
S752
R
E
K
Q
H
L
L
S
I
D
E
P
L
F
R
Site 75
Y797
D
C
L
S
G
I
Y
Y
R
L
P
G
L
E
Q
Site 76
T830
M
L
L
R
L
L
D
T
Y
R
D
K
I
P
E
Site 77
Y831
L
L
R
L
L
D
T
Y
R
D
K
I
P
E
E
Site 78
S887
R
L
L
S
L
V
D
S
A
G
Q
R
D
E
T
Site 79
T894
S
A
G
Q
R
D
E
T
G
N
N
S
V
Q
T
Site 80
T901
T
G
N
N
S
V
Q
T
V
F
Q
G
T
L
A
Site 81
T919
R
W
L
R
E
V
F
T
K
N
M
L
T
S
S
Site 82
S925
F
T
K
N
M
L
T
S
S
G
A
S
F
T
Y
Site 83
S926
T
K
N
M
L
T
S
S
G
A
S
F
T
Y
V
Site 84
Y932
S
S
G
A
S
F
T
Y
V
K
E
I
E
V
W
Site 85
T966
G
D
M
E
W
R
L
T
K
E
E
P
L
S
Q
Site 86
S972
L
T
K
E
E
P
L
S
Q
I
T
A
Y
C
N
Site 87
S990
D
T
K
G
L
E
D
S
V
A
K
T
F
E
K
Site 88
T994
L
E
D
S
V
A
K
T
F
E
K
C
I
I
E
Site 89
S1018
T
S
I
L
Q
G
F
S
Y
S
D
L
R
K
F
Site 90
Y1019
S
I
L
Q
G
F
S
Y
S
D
L
R
K
F
G
Site 91
S1036
L
S
A
V
I
T
K
S
W
P
R
T
A
D
N
Site 92
T1040
I
T
K
S
W
P
R
T
A
D
N
F
D
D
I
Site 93
S1126
I
W
Q
L
R
E
K
S
L
S
P
Q
D
E
K
Site 94
S1128
Q
L
R
E
K
S
L
S
P
Q
D
E
K
C
A
Site 95
S1159
K
E
K
R
C
V
D
S
L
L
K
M
C
G
N
Site 96
S1183
G
V
L
A
V
R
H
S
Q
D
L
S
S
K
R
Site 97
S1187
V
R
H
S
Q
D
L
S
S
K
R
L
N
D
T
Site 98
S1188
R
H
S
Q
D
L
S
S
K
R
L
N
D
T
M
Site 99
T1194
S
S
K
R
L
N
D
T
M
T
V
R
L
S
T
Site 100
T1196
K
R
L
N
D
T
M
T
V
R
L
S
T
S
S
Site 101
S1200
D
T
M
T
V
R
L
S
T
S
S
N
S
Q
R
Site 102
T1201
T
M
T
V
R
L
S
T
S
S
N
S
Q
R
A
Site 103
S1203
T
V
R
L
S
T
S
S
N
S
Q
R
A
T
H
Site 104
S1205
R
L
S
T
S
S
N
S
Q
R
A
T
H
Y
H
Site 105
T1209
S
S
N
S
Q
R
A
T
H
Y
H
L
S
S
Q
Site 106
Y1211
N
S
Q
R
A
T
H
Y
H
L
S
S
Q
V
Q
Site 107
S1215
A
T
H
Y
H
L
S
S
Q
V
Q
E
M
A
G
Site 108
S1245
R
E
A
A
E
P
L
S
E
P
K
E
D
Q
E
Site 109
S1258
Q
E
A
A
E
L
L
S
E
P
E
E
E
S
E
Site 110
S1264
L
S
E
P
E
E
E
S
E
R
H
I
L
E
L
Site 111
Y1277
E
L
Q
E
V
Y
D
Y
L
Y
Q
P
S
Y
R
Site 112
Y1279
Q
E
V
Y
D
Y
L
Y
Q
P
S
Y
R
K
F
Site 113
Y1283
D
Y
L
Y
Q
P
S
Y
R
K
F
I
K
L
H
Site 114
S1295
K
L
H
Q
D
L
K
S
G
E
V
T
L
A
E
Site 115
Y1314
F
K
D
F
V
N
K
Y
T
D
L
D
S
E
L
Site 116
T1326
S
E
L
K
I
M
C
T
V
D
H
Q
G
Q
R
Site 117
T1377
G
D
F
S
V
L
N
T
L
L
N
F
T
D
N
Site 118
T1392
F
D
D
F
R
R
E
T
L
D
Q
I
N
Q
E
Site 119
S1411
K
K
L
L
Q
D
I
S
E
A
R
C
K
G
L
Site 120
S1486
L
D
P
S
V
D
F
S
A
F
M
K
H
L
K
Site 121
Y1504
K
A
L
D
K
D
Q
Y
L
P
R
K
L
V
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation