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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GBA2
Full Name:
Non-lysosomal glucosylceramidase
Alias:
Beta-glucocerebrosidase 2;Glucosylceramidase 2
Type:
Mass (Da):
104649
Number AA:
927
UniProt ID:
Q9HCG7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T135
K
T
H
V
E
K
K
T
P
F
I
D
M
I
N
Site 2
S212
V
L
S
L
E
R
P
S
V
L
R
S
W
N
W
Site 3
S409
G
Q
C
R
L
E
F
S
L
A
W
D
M
P
R
Site 4
Y576
E
D
L
T
R
R
R
Y
L
M
S
G
V
M
A
Site 5
S579
T
R
R
R
Y
L
M
S
G
V
M
A
P
V
K
Site 6
S716
Q
D
I
Q
D
K
F
S
S
I
L
S
R
G
Q
Site 7
S717
D
I
Q
D
K
F
S
S
I
L
S
R
G
Q
E
Site 8
S720
D
K
F
S
S
I
L
S
R
G
Q
E
A
Y
E
Site 9
Y726
L
S
R
G
Q
E
A
Y
E
R
L
L
W
N
G
Site 10
Y735
R
L
L
W
N
G
R
Y
Y
N
Y
D
S
S
S
Site 11
Y736
L
L
W
N
G
R
Y
Y
N
Y
D
S
S
S
R
Site 12
Y738
W
N
G
R
Y
Y
N
Y
D
S
S
S
R
P
Q
Site 13
S740
G
R
Y
Y
N
Y
D
S
S
S
R
P
Q
S
R
Site 14
S741
R
Y
Y
N
Y
D
S
S
S
R
P
Q
S
R
S
Site 15
S742
Y
Y
N
Y
D
S
S
S
R
P
Q
S
R
S
V
Site 16
S746
D
S
S
S
R
P
Q
S
R
S
V
M
S
D
Q
Site 17
S748
S
S
R
P
Q
S
R
S
V
M
S
D
Q
C
A
Site 18
T770
C
G
L
G
E
G
D
T
E
V
F
P
T
Q
H
Site 19
T775
G
D
T
E
V
F
P
T
Q
H
V
V
R
A
L
Site 20
S813
P
H
G
V
P
D
K
S
S
V
Q
S
D
E
V
Site 21
S814
H
G
V
P
D
K
S
S
V
Q
S
D
E
V
W
Site 22
S817
P
D
K
S
S
V
Q
S
D
E
V
W
V
G
V
Site 23
T844
L
T
W
E
G
F
Q
T
A
E
G
C
Y
R
T
Site 24
T862
R
L
G
L
A
F
Q
T
P
E
A
Y
C
Q
Q
Site 25
S874
C
Q
Q
R
V
F
R
S
L
A
Y
M
R
P
L
Site 26
T907
W
P
K
V
K
Q
G
T
G
L
R
T
G
P
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation