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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1586
Full Name:
Uncharacterized protein KIAA1586
Alias:
Type:
Mass (Da):
89673
Number AA:
787
UniProt ID:
Q9HCI6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
D
P
G
S
E
I
I
E
S
V
P
Site 2
S11
P
G
S
E
I
I
E
S
V
P
P
A
G
P
E
Site 3
S20
P
P
A
G
P
E
A
S
E
S
T
T
D
E
N
Site 4
S22
A
G
P
E
A
S
E
S
T
T
D
E
N
E
D
Site 5
T24
P
E
A
S
E
S
T
T
D
E
N
E
D
D
I
Site 6
S35
E
D
D
I
Q
F
V
S
E
G
P
S
R
P
V
Site 7
S39
Q
F
V
S
E
G
P
S
R
P
V
L
E
Y
I
Site 8
S57
C
G
D
D
E
N
P
S
A
Y
Y
S
D
I
L
Site 9
Y59
D
D
E
N
P
S
A
Y
Y
S
D
I
L
F
P
Site 10
S61
E
N
P
S
A
Y
Y
S
D
I
L
F
P
K
M
Site 11
T88
V
K
K
V
K
T
D
T
E
N
N
E
V
S
K
Site 12
S101
S
K
N
H
C
R
L
S
K
A
K
E
P
H
F
Site 13
S121
P
I
I
E
E
K
P
S
L
S
S
K
K
E
I
Site 14
S165
K
L
G
C
K
D
C
S
A
V
R
H
L
G
S
Site 15
S172
S
A
V
R
H
L
G
S
K
A
E
K
H
V
H
Site 16
Y187
V
S
K
E
W
I
A
Y
L
V
T
P
N
G
S
Site 17
T190
E
W
I
A
Y
L
V
T
P
N
G
S
N
K
T
Site 18
T197
T
P
N
G
S
N
K
T
T
R
Q
A
S
L
R
Site 19
T198
P
N
G
S
N
K
T
T
R
Q
A
S
L
R
K
Site 20
S202
N
K
T
T
R
Q
A
S
L
R
K
K
I
R
E
Site 21
S213
K
I
R
E
H
D
V
S
K
A
H
G
K
I
Q
Site 22
S226
I
Q
D
L
L
K
E
S
T
N
D
S
I
C
N
Site 23
S230
L
K
E
S
T
N
D
S
I
C
N
L
V
H
K
Site 24
T246
N
N
K
N
I
D
A
T
V
K
V
F
N
T
V
Site 25
Y254
V
K
V
F
N
T
V
Y
S
L
V
K
H
N
R
Site 26
S255
K
V
F
N
T
V
Y
S
L
V
K
H
N
R
P
Site 27
S264
V
K
H
N
R
P
L
S
D
I
E
G
A
R
E
Site 28
S287
N
C
L
N
T
R
Y
S
A
T
R
I
A
E
H
Site 29
T404
G
R
K
S
G
V
A
T
K
L
L
E
N
F
P
Site 30
S426
L
N
H
R
L
Q
L
S
L
D
D
S
I
S
E
Site 31
S430
L
Q
L
S
L
D
D
S
I
S
E
I
K
Q
I
Site 32
S432
L
S
L
D
D
S
I
S
E
I
K
Q
I
N
H
Site 33
Y448
K
I
F
I
D
K
I
Y
S
I
Y
H
Q
P
N
Site 34
S449
I
F
I
D
K
I
Y
S
I
Y
H
Q
P
N
K
Site 35
Y451
I
D
K
I
Y
S
I
Y
H
Q
P
N
K
N
Q
Site 36
T464
N
Q
T
K
L
L
G
T
V
A
K
E
L
E
T
Site 37
S509
L
Y
M
H
F
S
H
S
Y
S
G
L
A
K
R
Site 38
S511
M
H
F
S
H
S
Y
S
G
L
A
K
R
L
A
Site 39
S540
L
E
E
F
S
V
L
S
T
A
L
Q
S
R
S
Site 40
T541
E
E
F
S
V
L
S
T
A
L
Q
S
R
S
T
Site 41
T548
T
A
L
Q
S
R
S
T
N
I
K
K
A
Q
K
Site 42
Y574
L
K
I
G
T
G
K
Y
E
S
Q
I
E
D
L
Site 43
S576
I
G
T
G
K
Y
E
S
Q
I
E
D
L
I
K
Site 44
S584
Q
I
E
D
L
I
K
S
D
K
F
K
D
I
P
Site 45
S620
H
M
N
L
R
L
L
S
D
R
N
H
E
D
I
Site 46
Y630
N
H
E
D
I
F
N
Y
F
D
L
L
E
P
S
Site 47
T638
F
D
L
L
E
P
S
T
W
P
Y
E
E
I
T
Site 48
Y641
L
E
P
S
T
W
P
Y
E
E
I
T
S
P
W
Site 49
Y664
H
L
C
K
I
L
K
Y
E
V
D
L
N
D
F
Site 50
S681
F
V
N
N
N
I
K
S
N
N
V
S
I
P
T
Site 51
S685
N
I
K
S
N
N
V
S
I
P
T
T
I
Y
K
Site 52
T689
N
N
V
S
I
P
T
T
I
Y
K
A
K
K
I
Site 53
S724
I
C
T
R
V
R
N
S
L
T
I
D
H
V
S
Site 54
T726
T
R
V
R
N
S
L
T
I
D
H
V
S
D
L
Site 55
T735
D
H
V
S
D
L
M
T
I
N
L
L
G
K
E
Site 56
T749
E
L
A
D
W
D
A
T
P
F
V
K
S
W
S
Site 57
T764
N
C
N
H
R
L
A
T
D
T
R
V
R
Q
K
Site 58
T766
N
H
R
L
A
T
D
T
R
V
R
Q
K
S
T
Site 59
S772
D
T
R
V
R
Q
K
S
T
K
V
F
H
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation