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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC4C
Full Name:
Leucine-rich repeat-containing protein 4C
Alias:
Netrin-G1 ligand
Type:
Mass (Da):
71950
Number AA:
640
UniProt ID:
Q9HCJ2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T76
E
V
P
D
G
I
S
T
N
T
R
L
L
N
L
Site 2
S108
H
L
E
I
L
Q
L
S
R
N
H
I
R
T
I
Site 3
T114
L
S
R
N
H
I
R
T
I
E
I
G
A
F
N
Site 4
T128
N
G
L
A
N
L
N
T
L
E
L
F
D
N
R
Site 5
T137
E
L
F
D
N
R
L
T
T
I
P
N
G
A
F
Site 6
S165
N
P
I
E
S
I
P
S
Y
A
F
N
R
I
P
Site 7
Y166
P
I
E
S
I
P
S
Y
A
F
N
R
I
P
S
Site 8
S173
Y
A
F
N
R
I
P
S
L
R
R
L
D
L
G
Site 9
S186
L
G
E
L
K
R
L
S
Y
I
S
E
G
A
F
Site 10
Y187
G
E
L
K
R
L
S
Y
I
S
E
G
A
F
E
Site 11
S189
L
K
R
L
S
Y
I
S
E
G
A
F
E
G
L
Site 12
S197
E
G
A
F
E
G
L
S
N
L
R
Y
L
N
L
Site 13
Y201
E
G
L
S
N
L
R
Y
L
N
L
A
M
C
N
Site 14
T216
L
R
E
I
P
N
L
T
P
L
I
K
L
D
E
Site 15
S227
K
L
D
E
L
D
L
S
G
N
H
L
S
A
I
Site 16
S232
D
L
S
G
N
H
L
S
A
I
R
P
G
S
F
Site 17
T288
L
L
P
H
D
L
F
T
P
L
H
H
L
E
R
Site 18
T324
K
D
M
A
P
S
N
T
A
C
C
A
R
C
N
Site 19
T332
A
C
C
A
R
C
N
T
P
P
N
L
K
G
R
Site 20
Y348
I
G
E
L
D
Q
N
Y
F
T
C
Y
A
P
V
Site 21
Y352
D
Q
N
Y
F
T
C
Y
A
P
V
I
V
E
P
Site 22
S378
A
E
L
K
C
R
A
S
T
S
L
T
S
V
S
Site 23
T379
E
L
K
C
R
A
S
T
S
L
T
S
V
S
W
Site 24
S383
R
A
S
T
S
L
T
S
V
S
W
I
T
P
N
Site 25
T417
T
L
N
F
T
N
V
T
V
Q
D
T
G
M
Y
Site 26
Y424
T
V
Q
D
T
G
M
Y
T
C
M
V
S
N
S
Site 27
S431
Y
T
C
M
V
S
N
S
V
G
N
T
T
A
S
Site 28
T435
V
S
N
S
V
G
N
T
T
A
S
A
T
L
N
Site 29
T449
N
V
T
A
A
T
T
T
P
F
S
Y
F
S
T
Site 30
T456
T
P
F
S
Y
F
S
T
V
T
V
E
T
M
E
Site 31
T472
S
Q
D
E
A
R
T
T
D
N
N
V
G
P
T
Site 32
T479
T
D
N
N
V
G
P
T
P
V
V
D
W
E
T
Site 33
T486
T
P
V
V
D
W
E
T
T
N
V
T
T
S
L
Site 34
S492
E
T
T
N
V
T
T
S
L
T
P
Q
S
T
R
Site 35
T494
T
N
V
T
T
S
L
T
P
Q
S
T
R
S
T
Site 36
S497
T
T
S
L
T
P
Q
S
T
R
S
T
E
K
T
Site 37
T501
T
P
Q
S
T
R
S
T
E
K
T
F
T
I
P
Site 38
T504
S
T
R
S
T
E
K
T
F
T
I
P
V
T
D
Site 39
T506
R
S
T
E
K
T
F
T
I
P
V
T
D
I
N
Site 40
Y548
A
V
M
L
V
I
F
Y
K
M
R
K
Q
H
H
Site 41
T565
N
H
H
A
P
T
R
T
V
E
I
I
N
V
D
Site 42
T579
D
D
E
I
T
G
D
T
P
M
E
S
H
L
P
Site 43
S583
T
G
D
T
P
M
E
S
H
L
P
M
P
A
I
Site 44
Y598
E
H
E
H
L
N
H
Y
N
S
Y
K
S
P
F
Site 45
Y601
H
L
N
H
Y
N
S
Y
K
S
P
F
N
H
T
Site 46
S616
T
T
V
N
T
I
N
S
I
H
S
S
V
H
E
Site 47
S631
P
L
L
I
R
M
N
S
K
D
N
V
Q
E
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation