KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZSWIM6
Full Name:
Zinc finger SWIM domain-containing protein 6
Alias:
Type:
Mass (Da):
133470
Number AA:
1215
UniProt ID:
Q9HCJ5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
G
G
G
G
G
G
G
S
S
G
G
G
G
G
A
Site 2
S28
G
G
G
G
G
G
S
S
G
G
G
G
G
A
G
Site 3
Y38
G
G
G
A
G
G
G
Y
S
S
A
C
R
P
G
Site 4
S39
G
G
A
G
G
G
Y
S
S
A
C
R
P
G
P
Site 5
S40
G
A
G
G
G
Y
S
S
A
C
R
P
G
P
R
Site 6
T71
G
L
L
P
P
G
K
T
Q
S
P
E
S
L
L
Site 7
S73
L
P
P
G
K
T
Q
S
P
E
S
L
L
D
I
Site 8
S76
G
K
T
Q
S
P
E
S
L
L
D
I
A
A
R
Site 9
Y111
P
V
Q
R
R
I
V
Y
W
S
F
P
R
S
E
Site 10
S113
Q
R
R
I
V
Y
W
S
F
P
R
S
E
R
E
Site 11
Y124
S
E
R
E
I
C
M
Y
S
S
F
N
T
G
G
Site 12
S125
E
R
E
I
C
M
Y
S
S
F
N
T
G
G
G
Site 13
S126
R
E
I
C
M
Y
S
S
F
N
T
G
G
G
A
Site 14
S141
A
G
G
P
G
D
D
S
G
G
G
G
G
A
G
Site 15
S155
G
G
G
G
G
G
G
S
S
S
S
P
A
A
T
Site 16
S156
G
G
G
G
G
G
S
S
S
S
P
A
A
T
S
Site 17
S157
G
G
G
G
G
S
S
S
S
P
A
A
T
S
A
Site 18
S158
G
G
G
G
S
S
S
S
P
A
A
T
S
A
A
Site 19
T162
S
S
S
S
P
A
A
T
S
A
A
A
T
S
A
Site 20
T203
A
A
D
G
G
D
E
T
R
L
P
F
R
R
G
Site 21
T234
F
H
L
S
G
T
V
T
E
P
A
I
Q
S
E
Site 22
T261
R
C
K
I
T
S
V
T
C
S
C
G
N
K
D
Site 23
Y281
H
V
V
A
L
S
L
Y
R
I
R
K
P
D
Q
Site 24
T298
L
H
L
P
I
S
E
T
L
F
Q
M
N
R
D
Site 25
Y313
Q
L
Q
K
F
V
Q
Y
L
I
T
V
H
H
T
Site 26
S335
K
L
A
D
E
I
L
S
Q
N
S
E
I
N
Q
Site 27
T350
V
H
G
A
P
D
P
T
A
G
A
S
I
D
D
Site 28
S377
E
Q
V
K
L
F
L
S
Q
G
G
Y
H
G
S
Site 29
Y381
L
F
L
S
Q
G
G
Y
H
G
S
G
K
Q
L
Site 30
S384
S
Q
G
G
Y
H
G
S
G
K
Q
L
N
L
L
Site 31
S404
E
M
L
K
M
R
D
S
N
G
A
R
M
L
T
Site 32
S424
F
M
A
D
P
R
L
S
L
W
R
Q
Q
G
T
Site 33
Y437
G
T
A
M
T
D
K
Y
R
Q
L
W
D
E
L
Site 34
S464
C
K
L
E
Q
K
A
S
W
L
K
Q
L
K
K
Site 35
S487
W
E
D
G
N
H
G
S
E
L
P
N
L
T
N
Site 36
S507
A
N
A
N
Q
D
S
S
N
R
P
H
R
T
V
Site 37
S536
S
H
L
Q
H
I
I
S
S
D
L
Y
T
N
Y
Site 38
Y540
H
I
I
S
S
D
L
Y
T
N
Y
C
Y
H
D
Site 39
Y543
S
S
D
L
Y
T
N
Y
C
Y
H
D
D
T
E
Site 40
Y545
D
L
Y
T
N
Y
C
Y
H
D
D
T
E
N
S
Site 41
S552
Y
H
D
D
T
E
N
S
L
F
D
S
R
G
W
Site 42
T568
L
W
H
E
H
V
P
T
A
C
A
R
V
D
A
Site 43
Y581
D
A
L
R
S
H
G
Y
P
R
E
A
L
R
L
Site 44
T595
L
A
I
A
I
V
N
T
L
R
R
Q
Q
Q
K
Site 45
T609
K
Q
L
E
M
F
R
T
Q
K
K
E
L
P
H
Site 46
S655
R
I
D
D
E
N
L
S
G
F
S
D
F
T
E
Site 47
T661
L
S
G
F
S
D
F
T
E
N
M
G
Q
C
K
Site 48
S686
K
F
L
E
E
G
E
S
Y
L
T
L
A
V
E
Site 49
Y710
R
I
M
P
D
G
L
Y
T
Q
E
K
V
C
R
Site 50
S724
R
N
E
E
Q
L
I
S
K
L
Q
E
I
E
L
Site 51
T734
Q
E
I
E
L
D
D
T
L
V
K
I
F
R
K
Site 52
Y752
F
L
L
E
A
G
P
Y
S
G
L
G
E
I
I
Site 53
S753
L
L
E
A
G
P
Y
S
G
L
G
E
I
I
H
Site 54
T768
R
E
S
V
P
M
H
T
F
A
K
Y
L
F
T
Site 55
Y772
P
M
H
T
F
A
K
Y
L
F
T
S
L
L
P
Site 56
Y786
P
H
D
A
E
L
A
Y
K
I
A
L
R
A
M
Site 57
S804
V
L
E
S
T
A
P
S
G
D
L
T
R
P
H
Site 58
T808
T
A
P
S
G
D
L
T
R
P
H
H
I
A
S
Site 59
S815
T
R
P
H
H
I
A
S
V
V
P
N
R
Y
P
Site 60
Y821
A
S
V
V
P
N
R
Y
P
R
W
F
T
L
S
Site 61
T826
N
R
Y
P
R
W
F
T
L
S
H
I
E
S
Q
Site 62
S832
F
T
L
S
H
I
E
S
Q
Q
C
E
L
A
S
Site 63
T843
E
L
A
S
T
M
L
T
A
A
K
G
D
V
R
Site 64
T854
G
D
V
R
R
L
E
T
V
L
E
S
I
Q
K
Site 65
S858
R
L
E
T
V
L
E
S
I
Q
K
N
I
H
S
Site 66
S865
S
I
Q
K
N
I
H
S
S
S
H
I
F
K
L
Site 67
S867
Q
K
N
I
H
S
S
S
H
I
F
K
L
A
Q
Site 68
T881
Q
D
A
F
K
I
A
T
L
M
D
S
L
P
D
Site 69
S885
K
I
A
T
L
M
D
S
L
P
D
I
T
L
L
Site 70
T906
G
L
Q
V
M
R
M
T
L
S
T
L
N
W
R
Site 71
T909
V
M
R
M
T
L
S
T
L
N
W
R
R
R
E
Site 72
T923
E
M
V
R
W
L
V
T
C
A
T
E
V
G
V
Site 73
Y931
C
A
T
E
V
G
V
Y
A
L
D
S
I
M
Q
Site 74
S978
H
Q
Q
E
K
L
A
S
S
A
R
T
L
A
L
Site 75
S979
Q
Q
E
K
L
A
S
S
A
R
T
L
A
L
Q
Site 76
Y1036
Q
L
F
T
I
A
R
Y
M
E
H
R
G
Y
P
Site 77
Y1042
R
Y
M
E
H
R
G
Y
P
M
R
A
Y
K
L
Site 78
Y1047
R
G
Y
P
M
R
A
Y
K
L
A
T
L
A
M
Site 79
S1097
I
I
P
L
V
V
K
S
V
K
C
A
T
V
L
Site 80
S1127
G
L
H
G
R
R
N
S
G
K
L
M
S
L
D
Site 81
S1132
R
N
S
G
K
L
M
S
L
D
K
A
P
L
R
Site 82
T1152
T
I
G
A
Y
I
N
T
T
H
S
R
L
T
H
Site 83
T1153
I
G
A
Y
I
N
T
T
H
S
R
L
T
H
I
Site 84
T1158
N
T
T
H
S
R
L
T
H
I
S
P
R
H
Y
Site 85
S1161
H
S
R
L
T
H
I
S
P
R
H
Y
S
E
F
Site 86
Y1165
T
H
I
S
P
R
H
Y
S
E
F
I
E
F
L
Site 87
S1166
H
I
S
P
R
H
Y
S
E
F
I
E
F
L
S
Site 88
S1173
S
E
F
I
E
F
L
S
K
A
R
E
T
F
L
Site 89
T1178
F
L
S
K
A
R
E
T
F
L
M
A
H
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation