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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZDBF2
Full Name:
DBF4-type zinc finger-containing protein 2
Alias:
DBF4-type zinc finger-containing 2; FLJ45338; KIAA1571; zinc finger, DBF-type containing 2
Type:
Mass (Da):
265620
Number AA:
UniProt ID:
Q9HCK1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
K
R
Q
G
Y
C
S
Y
C
R
V
Q
Y
N
N
Site 2
Y15
C
S
Y
C
R
V
Q
Y
N
N
L
E
Q
H
L
Site 3
S29
L
F
S
A
Q
H
R
S
L
T
R
Q
S
R
R
Site 4
T31
S
A
Q
H
R
S
L
T
R
Q
S
R
R
Q
I
Site 5
S34
H
R
S
L
T
R
Q
S
R
R
Q
I
C
T
S
Site 6
T40
Q
S
R
R
Q
I
C
T
S
S
L
M
E
R
F
Site 7
S41
S
R
R
Q
I
C
T
S
S
L
M
E
R
F
L
Site 8
S42
R
R
Q
I
C
T
S
S
L
M
E
R
F
L
Q
Site 9
Y57
D
V
L
Q
H
H
P
Y
H
C
Q
E
S
S
S
Site 10
S64
Y
H
C
Q
E
S
S
S
T
Q
D
E
T
H
V
Site 11
T65
H
C
Q
E
S
S
S
T
Q
D
E
T
H
V
N
Site 12
T69
S
S
S
T
Q
D
E
T
H
V
N
T
G
S
S
Site 13
S75
E
T
H
V
N
T
G
S
S
S
E
V
V
H
L
Site 14
S77
H
V
N
T
G
S
S
S
E
V
V
H
L
D
D
Site 15
S87
V
H
L
D
D
A
F
S
E
E
E
E
E
D
E
Site 16
T103
K
V
E
D
E
D
A
T
E
E
R
P
S
E
V
Site 17
S108
D
A
T
E
E
R
P
S
E
V
S
E
P
I
E
Site 18
S111
E
E
R
P
S
E
V
S
E
P
I
E
E
L
H
Site 19
S119
E
P
I
E
E
L
H
S
R
P
H
K
S
Q
E
Site 20
S124
L
H
S
R
P
H
K
S
Q
E
G
T
Q
E
V
Site 21
T128
P
H
K
S
Q
E
G
T
Q
E
V
S
V
R
P
Site 22
S132
Q
E
G
T
Q
E
V
S
V
R
P
S
V
I
Q
Site 23
S136
Q
E
V
S
V
R
P
S
V
I
Q
K
L
E
K
Site 24
T171
L
V
D
I
G
Q
A
T
N
N
R
S
N
L
V
Site 25
S194
P
A
S
C
L
P
E
S
S
N
D
R
P
V
T
Site 26
T201
S
S
N
D
R
P
V
T
A
N
T
T
S
L
P
Site 27
S215
P
P
A
A
H
L
D
S
V
S
K
C
D
P
N
Site 28
S217
A
A
H
L
D
S
V
S
K
C
D
P
N
K
V
Site 29
Y227
D
P
N
K
V
E
K
Y
L
E
Q
P
D
G
A
Site 30
S235
L
E
Q
P
D
G
A
S
R
N
P
V
P
S
S
Site 31
S241
A
S
R
N
P
V
P
S
S
H
V
E
T
T
S
Site 32
S242
S
R
N
P
V
P
S
S
H
V
E
T
T
S
F
Site 33
T246
V
P
S
S
H
V
E
T
T
S
F
S
Y
Q
K
Site 34
S248
S
S
H
V
E
T
T
S
F
S
Y
Q
K
H
K
Site 35
S257
S
Y
Q
K
H
K
E
S
N
R
K
S
L
R
M
Site 36
S261
H
K
E
S
N
R
K
S
L
R
M
N
S
D
K
Site 37
S266
R
K
S
L
R
M
N
S
D
K
L
V
L
W
K
Site 38
S277
V
L
W
K
D
V
K
S
Q
G
K
T
L
S
A
Site 39
T281
D
V
K
S
Q
G
K
T
L
S
A
G
L
K
F
Site 40
S283
K
S
Q
G
K
T
L
S
A
G
L
K
F
H
E
Site 41
T294
K
F
H
E
R
M
G
T
K
G
S
L
R
V
K
Site 42
S297
E
R
M
G
T
K
G
S
L
R
V
K
S
P
S
Site 43
S302
K
G
S
L
R
V
K
S
P
S
K
L
A
V
N
Site 44
S304
S
L
R
V
K
S
P
S
K
L
A
V
N
P
N
Site 45
T313
L
A
V
N
P
N
K
T
D
M
P
S
N
K
G
Site 46
S317
P
N
K
T
D
M
P
S
N
K
G
I
F
E
D
Site 47
S370
E
M
K
F
D
C
I
S
L
Q
S
A
S
D
Q
Site 48
S373
F
D
C
I
S
L
Q
S
A
S
D
Q
P
Q
E
Site 49
S375
C
I
S
L
Q
S
A
S
D
Q
P
Q
E
T
A
Site 50
S386
Q
E
T
A
Q
D
L
S
L
W
K
E
E
Q
I
Site 51
Y399
Q
I
D
Q
E
D
N
Y
E
S
R
G
S
E
M
Site 52
S401
D
Q
E
D
N
Y
E
S
R
G
S
E
M
S
F
Site 53
S404
D
N
Y
E
S
R
G
S
E
M
S
F
D
C
S
Site 54
S407
E
S
R
G
S
E
M
S
F
D
C
S
S
S
F
Site 55
S411
S
E
M
S
F
D
C
S
S
S
F
H
S
L
T
Site 56
S412
E
M
S
F
D
C
S
S
S
F
H
S
L
T
D
Site 57
S413
M
S
F
D
C
S
S
S
F
H
S
L
T
D
Q
Site 58
S416
D
C
S
S
S
F
H
S
L
T
D
Q
S
K
V
Site 59
T418
S
S
S
F
H
S
L
T
D
Q
S
K
V
S
A
Site 60
S431
S
A
K
E
V
N
L
S
K
E
V
R
T
D
V
Site 61
Y440
E
V
R
T
D
V
Q
Y
K
N
N
K
S
Y
V
Site 62
S445
V
Q
Y
K
N
N
K
S
Y
V
S
K
I
S
S
Site 63
Y446
Q
Y
K
N
N
K
S
Y
V
S
K
I
S
S
D
Site 64
S448
K
N
N
K
S
Y
V
S
K
I
S
S
D
C
D
Site 65
S452
S
Y
V
S
K
I
S
S
D
C
D
D
I
L
H
Site 66
T462
D
D
I
L
H
L
V
T
N
Q
S
Q
M
I
V
Site 67
S465
L
H
L
V
T
N
Q
S
Q
M
I
V
K
E
I
Site 68
S473
Q
M
I
V
K
E
I
S
L
Q
N
A
R
H
I
Site 69
S481
L
Q
N
A
R
H
I
S
L
V
D
Q
S
Y
E
Site 70
S486
H
I
S
L
V
D
Q
S
Y
E
S
S
S
S
E
Site 71
Y487
I
S
L
V
D
Q
S
Y
E
S
S
S
S
E
T
Site 72
S489
L
V
D
Q
S
Y
E
S
S
S
S
E
T
N
F
Site 73
S490
V
D
Q
S
Y
E
S
S
S
S
E
T
N
F
D
Site 74
S492
Q
S
Y
E
S
S
S
S
E
T
N
F
D
C
D
Site 75
S501
T
N
F
D
C
D
A
S
P
Q
S
T
S
D
Y
Site 76
S504
D
C
D
A
S
P
Q
S
T
S
D
Y
P
Q
Q
Site 77
S506
D
A
S
P
Q
S
T
S
D
Y
P
Q
Q
S
V
Site 78
Y508
S
P
Q
S
T
S
D
Y
P
Q
Q
S
V
T
E
Site 79
S512
T
S
D
Y
P
Q
Q
S
V
T
E
V
N
L
P
Site 80
Y531
I
G
L
V
D
K
N
Y
G
S
S
S
S
E
V
Site 81
S533
L
V
D
K
N
Y
G
S
S
S
S
E
V
S
A
Site 82
S534
V
D
K
N
Y
G
S
S
S
S
E
V
S
A
D
Site 83
S535
D
K
N
Y
G
S
S
S
S
E
V
S
A
D
S
Site 84
S536
K
N
Y
G
S
S
S
S
E
V
S
A
D
S
V
Site 85
S539
G
S
S
S
S
E
V
S
A
D
S
V
F
P
L
Site 86
S548
D
S
V
F
P
L
Q
S
V
V
D
R
P
P
V
Site 87
T568
K
L
R
K
K
A
H
T
S
L
V
D
N
Y
G
Site 88
S569
L
R
K
K
A
H
T
S
L
V
D
N
Y
G
S
Site 89
Y574
H
T
S
L
V
D
N
Y
G
S
S
C
S
E
T
Site 90
S576
S
L
V
D
N
Y
G
S
S
C
S
E
T
S
F
Site 91
S577
L
V
D
N
Y
G
S
S
C
S
E
T
S
F
D
Site 92
S579
D
N
Y
G
S
S
C
S
E
T
S
F
D
C
D
Site 93
T581
Y
G
S
S
C
S
E
T
S
F
D
C
D
V
S
Site 94
S582
G
S
S
C
S
E
T
S
F
D
C
D
V
S
L
Site 95
S588
T
S
F
D
C
D
V
S
L
E
S
V
V
D
H
Site 96
S591
D
C
D
V
S
L
E
S
V
V
D
H
P
Q
L
Site 97
T599
V
V
D
H
P
Q
L
T
V
K
G
R
N
L
K
Site 98
S620
K
H
K
K
R
K
P
S
S
A
K
A
H
L
D
Site 99
S621
H
K
K
R
K
P
S
S
A
K
A
H
L
D
C
Site 100
T634
D
C
D
V
S
L
G
T
V
A
D
E
S
Q
R
Site 101
S639
L
G
T
V
A
D
E
S
Q
R
A
V
E
K
I
Site 102
S680
D
A
Q
L
A
D
Q
S
Q
V
A
E
I
E
R
Site 103
S698
D
V
D
L
E
N
K
S
V
Q
S
S
R
S
S
Site 104
S701
L
E
N
K
S
V
Q
S
S
R
S
S
L
S
S
Site 105
S702
E
N
K
S
V
Q
S
S
R
S
S
L
S
S
D
Site 106
S704
K
S
V
Q
S
S
R
S
S
L
S
S
D
S
P
Site 107
S705
S
V
Q
S
S
R
S
S
L
S
S
D
S
P
A
Site 108
S707
Q
S
S
R
S
S
L
S
S
D
S
P
A
S
L
Site 109
S708
S
S
R
S
S
L
S
S
D
S
P
A
S
L
Y
Site 110
S710
R
S
S
L
S
S
D
S
P
A
S
L
Y
H
S
Site 111
S713
L
S
S
D
S
P
A
S
L
Y
H
S
A
H
D
Site 112
Y715
S
D
S
P
A
S
L
Y
H
S
A
H
D
E
P
Site 113
S717
S
P
A
S
L
Y
H
S
A
H
D
E
P
Q
E
Site 114
S742
N
I
D
M
E
V
R
S
Y
D
C
S
S
S
E
Site 115
Y743
I
D
M
E
V
R
S
Y
D
C
S
S
S
E
L
Site 116
S746
E
V
R
S
Y
D
C
S
S
S
E
L
T
F
D
Site 117
S747
V
R
S
Y
D
C
S
S
S
E
L
T
F
D
S
Site 118
S748
R
S
Y
D
C
S
S
S
E
L
T
F
D
S
D
Site 119
T751
D
C
S
S
S
E
L
T
F
D
S
D
P
P
L
Site 120
S754
S
S
E
L
T
F
D
S
D
P
P
L
L
S
V
Site 121
S760
D
S
D
P
P
L
L
S
V
T
E
Q
S
H
L
Site 122
S782
H
I
D
L
E
D
E
S
C
E
S
D
S
S
E
Site 123
S785
L
E
D
E
S
C
E
S
D
S
S
E
I
T
F
Site 124
S788
E
S
C
E
S
D
S
S
E
I
T
F
D
S
D
Site 125
T791
E
S
D
S
S
E
I
T
F
D
S
D
I
P
L
Site 126
S794
S
S
E
I
T
F
D
S
D
I
P
L
Y
S
V
Site 127
Y799
F
D
S
D
I
P
L
Y
S
V
I
D
Q
P
E
Site 128
S800
D
S
D
I
P
L
Y
S
V
I
D
Q
P
E
V
Site 129
Y810
D
Q
P
E
V
A
V
Y
E
E
E
T
V
D
L
Site 130
T814
V
A
V
Y
E
E
E
T
V
D
L
E
S
K
S
Site 131
S819
E
E
T
V
D
L
E
S
K
S
N
E
S
C
V
Site 132
S821
T
V
D
L
E
S
K
S
N
E
S
C
V
S
E
Site 133
S824
L
E
S
K
S
N
E
S
C
V
S
E
I
T
F
Site 134
S827
K
S
N
E
S
C
V
S
E
I
T
F
D
S
D
Site 135
S833
V
S
E
I
T
F
D
S
D
I
P
L
H
S
G
Site 136
S839
D
S
D
I
P
L
H
S
G
N
D
H
P
E
V
Site 137
S868
E
R
K
N
D
E
P
S
G
S
E
I
S
S
D
Site 138
S870
K
N
D
E
P
S
G
S
E
I
S
S
D
S
H
Site 139
S874
P
S
G
S
E
I
S
S
D
S
H
A
P
L
H
Site 140
S876
G
S
E
I
S
S
D
S
H
A
P
L
H
S
V
Site 141
S882
D
S
H
A
P
L
H
S
V
T
N
S
P
E
V
Site 142
T884
H
A
P
L
H
S
V
T
N
S
P
E
V
A
V
Site 143
S886
P
L
H
S
V
T
N
S
P
E
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P
S
T
P
V
R
A
Y
D
Site 296
T2321
G
R
Q
K
G
P
S
T
P
V
R
A
Y
D
L
Site 297
Y2326
P
S
T
P
V
R
A
Y
D
L
R
S
S
S
C
Site 298
S2330
V
R
A
Y
D
L
R
S
S
S
C
L
Q
Q
R
Site 299
S2331
R
A
Y
D
L
R
S
S
S
C
L
Q
Q
R
E
Site 300
S2332
A
Y
D
L
R
S
S
S
C
L
Q
Q
R
E
R
Site 301
T2342
Q
Q
R
E
R
M
M
T
R
L
A
N
K
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation