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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCDH18
Full Name:
Protocadherin-18
Alias:
KIAA1562; PCD18; PCDH68L; protocadherin 18; protocadherin 68-like protein; protocadherin-18
Type:
Adhesion
Mass (Da):
126150
Number AA:
UniProt ID:
Q9HCL0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007420
GO:0007156
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S432
R
E
K
R
S
E
Y
S
L
T
V
I
A
E
D
Site 2
S733
R
E
K
K
D
T
R
S
Y
N
C
R
V
A
E
Site 3
Y734
E
K
K
D
T
R
S
Y
N
C
R
V
A
E
S
Site 4
T742
N
C
R
V
A
E
S
T
Y
Q
H
H
P
K
R
Site 5
Y743
C
R
V
A
E
S
T
Y
Q
H
H
P
K
R
P
Site 6
S751
Q
H
H
P
K
R
P
S
R
Q
I
H
K
G
D
Site 7
T760
Q
I
H
K
G
D
I
T
L
V
P
T
I
N
G
Site 8
T768
L
V
P
T
I
N
G
T
L
P
I
R
S
H
H
Site 9
S773
N
G
T
L
P
I
R
S
H
H
R
S
S
P
S
Site 10
S777
P
I
R
S
H
H
R
S
S
P
S
S
S
P
T
Site 11
S778
I
R
S
H
H
R
S
S
P
S
S
S
P
T
L
Site 12
S780
S
H
H
R
S
S
P
S
S
S
P
T
L
E
R
Site 13
S781
H
H
R
S
S
P
S
S
S
P
T
L
E
R
G
Site 14
S782
H
R
S
S
P
S
S
S
P
T
L
E
R
G
Q
Site 15
T784
S
S
P
S
S
S
P
T
L
E
R
G
Q
M
G
Site 16
S792
L
E
R
G
Q
M
G
S
R
Q
S
H
N
S
H
Site 17
S795
G
Q
M
G
S
R
Q
S
H
N
S
H
Q
S
L
Site 18
S798
G
S
R
Q
S
H
N
S
H
Q
S
L
N
S
L
Site 19
S801
Q
S
H
N
S
H
Q
S
L
N
S
L
V
T
I
Site 20
S804
N
S
H
Q
S
L
N
S
L
V
T
I
S
S
N
Site 21
S810
N
S
L
V
T
I
S
S
N
H
V
P
E
N
F
Site 22
S818
N
H
V
P
E
N
F
S
L
E
L
T
H
A
T
Site 23
T822
E
N
F
S
L
E
L
T
H
A
T
P
A
V
E
Site 24
T825
S
L
E
L
T
H
A
T
P
A
V
E
Q
V
S
Site 25
S836
E
Q
V
S
Q
L
L
S
M
L
H
Q
G
Q
Y
Site 26
Y843
S
M
L
H
Q
G
Q
Y
Q
P
R
P
S
F
R
Site 27
S848
G
Q
Y
Q
P
R
P
S
F
R
G
N
K
Y
S
Site 28
Y854
P
S
F
R
G
N
K
Y
S
R
S
Y
R
Y
A
Site 29
S855
S
F
R
G
N
K
Y
S
R
S
Y
R
Y
A
L
Site 30
S857
R
G
N
K
Y
S
R
S
Y
R
Y
A
L
Q
D
Site 31
Y858
G
N
K
Y
S
R
S
Y
R
Y
A
L
Q
D
M
Site 32
S869
L
Q
D
M
D
K
F
S
L
K
D
S
G
R
G
Site 33
S873
D
K
F
S
L
K
D
S
G
R
G
D
S
E
A
Site 34
S878
K
D
S
G
R
G
D
S
E
A
G
D
S
D
Y
Site 35
S883
G
D
S
E
A
G
D
S
D
Y
D
L
G
R
D
Site 36
Y885
S
E
A
G
D
S
D
Y
D
L
G
R
D
S
P
Site 37
S891
D
Y
D
L
G
R
D
S
P
I
D
R
L
L
G
Site 38
S938
C
W
M
P
P
L
P
S
P
S
S
D
Y
R
S
Site 39
S940
M
P
P
L
P
S
P
S
S
D
Y
R
S
N
M
Site 40
S941
P
P
L
P
S
P
S
S
D
Y
R
S
N
M
F
Site 41
Y943
L
P
S
P
S
S
D
Y
R
S
N
M
F
I
P
Site 42
S945
S
P
S
S
D
Y
R
S
N
M
F
I
P
G
E
Site 43
T956
I
P
G
E
E
F
P
T
Q
P
Q
Q
Q
H
P
Site 44
S966
Q
Q
Q
H
P
H
Q
S
L
E
D
D
A
Q
P
Site 45
S976
D
D
A
Q
P
A
D
S
G
E
K
K
K
S
F
Site 46
S982
D
S
G
E
K
K
K
S
F
S
T
F
G
K
D
Site 47
S984
G
E
K
K
K
S
F
S
T
F
G
K
D
S
P
Site 48
T985
E
K
K
K
S
F
S
T
F
G
K
D
S
P
N
Site 49
S990
F
S
T
F
G
K
D
S
P
N
D
E
D
T
G
Site 50
T996
D
S
P
N
D
E
D
T
G
D
T
S
T
S
S
Site 51
T999
N
D
E
D
T
G
D
T
S
T
S
S
L
L
S
Site 52
S1000
D
E
D
T
G
D
T
S
T
S
S
L
L
S
E
Site 53
T1001
E
D
T
G
D
T
S
T
S
S
L
L
S
E
M
Site 54
S1002
D
T
G
D
T
S
T
S
S
L
L
S
E
M
S
Site 55
S1003
T
G
D
T
S
T
S
S
L
L
S
E
M
S
S
Site 56
S1006
T
S
T
S
S
L
L
S
E
M
S
S
V
F
Q
Site 57
S1019
F
Q
R
L
L
P
P
S
L
D
T
Y
S
E
C
Site 58
T1022
L
L
P
P
S
L
D
T
Y
S
E
C
S
E
V
Site 59
Y1023
L
P
P
S
L
D
T
Y
S
E
C
S
E
V
D
Site 60
S1024
P
P
S
L
D
T
Y
S
E
C
S
E
V
D
R
Site 61
S1027
L
D
T
Y
S
E
C
S
E
V
D
R
S
N
S
Site 62
S1032
E
C
S
E
V
D
R
S
N
S
L
E
R
R
K
Site 63
S1034
S
E
V
D
R
S
N
S
L
E
R
R
K
G
P
Site 64
T1046
K
G
P
L
P
A
K
T
V
G
Y
P
Q
G
V
Site 65
T1066
S
T
H
F
Q
N
P
T
T
N
C
G
P
P
L
Site 66
T1067
T
H
F
Q
N
P
T
T
N
C
G
P
P
L
G
Site 67
S1077
G
P
P
L
G
T
H
S
S
V
Q
P
S
S
K
Site 68
S1078
P
P
L
G
T
H
S
S
V
Q
P
S
S
K
W
Site 69
S1082
T
H
S
S
V
Q
P
S
S
K
W
L
P
A
M
Site 70
S1083
H
S
S
V
Q
P
S
S
K
W
L
P
A
M
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation