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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLXNA4
Full Name:
Plexin-A4
Alias:
DKFZp566O0546; FLJ35026; FLJ38287; PLEXA4; PLXA4
Type:
Intracellular, Membrane, Integral membrane protein
Mass (Da):
212455
Number AA:
1894
UniProt ID:
Q9HCM2
International Prot ID:
IPI00165931
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005622
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S515
P
E
F
M
A
R
S
S
Q
L
Y
Y
F
M
T
Site 2
S946
P
E
F
M
A
R
S
S
Q
L
Y
Y
F
M
T
Site 3
S1002
L
F
H
R
R
S
P
S
Y
I
V
C
N
T
T
Site 4
Y1003
F
H
R
R
S
P
S
Y
I
V
C
N
T
T
S
Site 5
T1009
S
Y
I
V
C
N
T
T
S
S
D
E
V
L
E
Site 6
Y1138
L
N
K
T
N
F
T
Y
Y
P
N
P
V
F
E
Site 7
Y1139
N
K
T
N
F
T
Y
Y
P
N
P
V
F
E
A
Site 8
S1232
M
V
Y
I
A
P
D
S
P
L
S
L
P
A
I
Site 9
S1235
I
A
P
D
S
P
L
S
L
P
A
I
V
S
I
Site 10
Y1260
I
V
A
V
L
I
A
Y
K
R
K
S
R
E
S
Site 11
S1264
L
I
A
Y
K
R
K
S
R
E
S
D
L
T
L
Site 12
S1267
Y
K
R
K
S
R
E
S
D
L
T
L
K
R
L
Site 13
T1270
K
S
R
E
S
D
L
T
L
K
R
L
Q
M
Q
Site 14
Y1317
A
G
I
P
F
L
D
Y
R
T
Y
T
M
R
V
Site 15
Y1320
P
F
L
D
Y
R
T
Y
T
M
R
V
L
F
P
Site 16
Y1343
R
D
L
E
V
P
G
Y
R
Q
E
R
V
E
K
Site 17
S1374
S
F
I
R
T
L
E
S
Q
R
S
F
S
M
R
Site 18
S1377
R
T
L
E
S
Q
R
S
F
S
M
R
D
R
G
Site 19
S1379
L
E
S
Q
R
S
F
S
M
R
D
R
G
N
V
Site 20
Y1400
V
L
Q
S
K
L
E
Y
A
T
D
V
L
K
Q
Site 21
S1419
L
I
D
K
N
L
E
S
K
N
H
P
K
L
L
Site 22
T1430
P
K
L
L
L
R
R
T
E
S
V
A
E
K
M
Site 23
S1432
L
L
L
R
R
T
E
S
V
A
E
K
M
L
T
Site 24
T1478
K
G
P
I
D
A
I
T
G
E
A
R
Y
S
L
Site 25
Y1483
A
I
T
G
E
A
R
Y
S
L
S
E
D
K
L
Site 26
S1484
I
T
G
E
A
R
Y
S
L
S
E
D
K
L
I
Site 27
S1486
G
E
A
R
Y
S
L
S
E
D
K
L
I
R
Q
Site 28
Y1497
L
I
R
Q
Q
I
D
Y
K
T
L
V
L
S
C
Site 29
T1499
R
Q
Q
I
D
Y
K
T
L
V
L
S
C
V
S
Site 30
S1503
D
Y
K
T
L
V
L
S
C
V
S
P
D
N
A
Site 31
S1512
V
S
P
D
N
A
N
S
P
E
V
P
V
K
I
Site 32
S1543
I
F
K
N
V
P
C
S
H
R
P
K
A
A
D
Site 33
S1559
D
L
E
W
R
Q
G
S
G
A
R
M
I
L
Q
Site 34
T1572
L
Q
D
E
D
I
T
T
K
I
E
N
D
W
K
Site 35
T1583
N
D
W
K
R
L
N
T
L
A
H
Y
Q
V
P
Site 36
Y1587
R
L
N
T
L
A
H
Y
Q
V
P
D
G
S
V
Site 37
T1603
A
L
V
S
K
Q
V
T
A
Y
N
A
V
N
N
Site 38
Y1605
V
S
K
Q
V
T
A
Y
N
A
V
N
N
S
T
Site 39
S1611
A
Y
N
A
V
N
N
S
T
V
S
R
T
S
A
Site 40
T1612
Y
N
A
V
N
N
S
T
V
S
R
T
S
A
S
Site 41
S1614
A
V
N
N
S
T
V
S
R
T
S
A
S
K
Y
Site 42
S1617
N
S
T
V
S
R
T
S
A
S
K
Y
E
N
M
Site 43
Y1621
S
R
T
S
A
S
K
Y
E
N
M
I
R
Y
T
Site 44
Y1627
K
Y
E
N
M
I
R
Y
T
G
S
P
D
S
L
Site 45
T1628
Y
E
N
M
I
R
Y
T
G
S
P
D
S
L
R
Site 46
S1630
N
M
I
R
Y
T
G
S
P
D
S
L
R
S
R
Site 47
S1633
R
Y
T
G
S
P
D
S
L
R
S
R
T
P
M
Site 48
S1636
G
S
P
D
S
L
R
S
R
T
P
M
I
T
P
Site 49
T1638
P
D
S
L
R
S
R
T
P
M
I
T
P
D
L
Site 50
T1642
R
S
R
T
P
M
I
T
P
D
L
E
S
G
V
Site 51
S1670
Q
K
E
G
D
R
G
S
K
M
V
S
E
I
Y
Site 52
S1674
D
R
G
S
K
M
V
S
E
I
Y
L
T
R
L
Site 53
T1687
R
L
L
A
T
K
G
T
L
Q
K
F
V
D
D
Site 54
S1701
D
L
F
E
T
I
F
S
T
A
H
R
G
S
A
Site 55
S1781
V
A
Q
T
F
M
D
S
C
S
T
S
E
H
R
Site 56
S1783
Q
T
F
M
D
S
C
S
T
S
E
H
R
L
G
Site 57
S1785
F
M
D
S
C
S
T
S
E
H
R
L
G
K
D
Site 58
S1793
E
H
R
L
G
K
D
S
P
S
N
K
L
L
Y
Site 59
S1795
R
L
G
K
D
S
P
S
N
K
L
L
Y
A
K
Site 60
Y1800
S
P
S
N
K
L
L
Y
A
K
D
I
P
S
Y
Site 61
Y1807
Y
A
K
D
I
P
S
Y
K
N
W
V
E
R
Y
Site 62
Y1814
Y
K
N
W
V
E
R
Y
Y
S
D
I
G
K
M
Site 63
Y1815
K
N
W
V
E
R
Y
Y
S
D
I
G
K
M
P
Site 64
Y1832
S
D
Q
D
M
N
A
Y
L
A
E
Q
S
R
M
Site 65
S1855
S
A
L
S
E
I
F
S
Y
V
G
K
Y
S
E
Site 66
Y1856
A
L
S
E
I
F
S
Y
V
G
K
Y
S
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation