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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPN1
Full Name:
GPN-loop GTPase 1
Alias:
ATPBD1A; MBD2-interacting protein; MBDIN; NTPBP; XAB1; XPA-binding protein 1
Type:
Mass (Da):
41740
Number AA:
374
UniProt ID:
Q9HCN4
International Prot ID:
IPI00027035
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0017111
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
A
A
S
A
A
A
A
E
L
Q
Site 2
S13
A
A
A
E
L
Q
A
S
G
G
P
R
H
P
V
Site 3
T34
M
A
G
S
G
K
T
T
F
V
Q
R
L
T
G
Site 4
T40
T
T
F
V
Q
R
L
T
G
H
L
H
A
Q
G
Site 5
T48
G
H
L
H
A
Q
G
T
P
P
Y
V
I
N
L
Site 6
Y51
H
A
Q
G
T
P
P
Y
V
I
N
L
D
P
A
Site 7
T73
A
N
I
D
I
R
D
T
V
K
Y
K
E
V
M
Site 8
Y76
D
I
R
D
T
V
K
Y
K
E
V
M
K
Q
Y
Site 9
Y118
K
A
Q
N
M
S
K
Y
V
L
I
D
T
P
G
Site 10
T161
V
M
D
T
S
R
S
T
N
P
V
T
F
M
S
Site 11
T165
S
R
S
T
N
P
V
T
F
M
S
N
M
L
Y
Site 12
Y219
A
L
N
Q
E
T
T
Y
V
S
N
L
T
R
S
Site 13
S228
S
N
L
T
R
S
M
S
L
V
L
D
E
F
Y
Site 14
Y269
A
E
E
Y
E
R
E
Y
R
P
E
Y
E
R
L
Site 15
Y273
E
R
E
Y
R
P
E
Y
E
R
L
K
K
S
L
Site 16
S279
E
Y
E
R
L
K
K
S
L
A
N
A
E
S
Q
Site 17
S285
K
S
L
A
N
A
E
S
Q
Q
Q
R
E
Q
L
Site 18
S301
R
L
R
K
D
M
G
S
V
A
L
D
A
G
T
Site 19
T308
S
V
A
L
D
A
G
T
A
K
D
S
L
S
P
Site 20
S312
D
A
G
T
A
K
D
S
L
S
P
V
L
H
P
Site 21
S314
G
T
A
K
D
S
L
S
P
V
L
H
P
S
D
Site 22
S320
L
S
P
V
L
H
P
S
D
L
I
L
T
R
G
Site 23
T325
H
P
S
D
L
I
L
T
R
G
T
L
D
E
E
Site 24
T328
D
L
I
L
T
R
G
T
L
D
E
E
D
E
E
Site 25
S338
E
E
D
E
E
A
D
S
D
T
D
D
I
D
H
Site 26
T340
D
E
E
A
D
S
D
T
D
D
I
D
H
R
V
Site 27
T348
D
D
I
D
H
R
V
T
E
E
S
H
E
E
P
Site 28
S351
D
H
R
V
T
E
E
S
H
E
E
P
A
F
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation