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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EPB41L4A
Full Name:
Band 4.1-like protein 4A
Alias:
E41LA; EPB41L4; Erythrocyte membrane protein band 4.1 like 4A; NBL4
Type:
Cytoskeletal protein
Mass (Da):
69375
Number AA:
598
UniProt ID:
Q9HCS5
International Prot ID:
IPI00030794
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0008092
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
L
L
D
E
S
K
L
T
L
T
T
Q
Q
Q
G
Site 2
S35
Q
Q
Q
G
I
K
K
S
T
K
G
S
V
V
L
Site 3
Y61
I
D
Y
F
G
L
R
Y
C
D
R
S
H
Q
T
Site 4
Y69
C
D
R
S
H
Q
T
Y
W
L
D
P
A
K
T
Site 5
T76
Y
W
L
D
P
A
K
T
L
A
E
H
K
E
L
Site 6
T86
E
H
K
E
L
I
N
T
G
P
P
Y
T
L
Y
Site 7
Y90
L
I
N
T
G
P
P
Y
T
L
Y
F
G
I
K
Site 8
Y93
T
G
P
P
Y
T
L
Y
F
G
I
K
F
Y
A
Site 9
Y113
L
K
E
E
I
T
R
Y
Q
F
F
L
Q
V
K
Site 10
Y150
I
Q
S
E
L
G
D
Y
D
P
Y
K
H
T
A
Site 11
Y153
E
L
G
D
Y
D
P
Y
K
H
T
A
G
Y
V
Site 12
Y159
P
Y
K
H
T
A
G
Y
V
S
E
Y
R
F
V
Site 13
S161
K
H
T
A
G
Y
V
S
E
Y
R
F
V
P
D
Site 14
T183
A
I
E
R
I
H
K
T
L
M
G
Q
I
P
S
Site 15
S190
T
L
M
G
Q
I
P
S
E
A
E
L
N
Y
L
Site 16
Y196
P
S
E
A
E
L
N
Y
L
R
T
A
K
S
L
Site 17
S202
N
Y
L
R
T
A
K
S
L
E
M
Y
G
V
D
Site 18
Y206
T
A
K
S
L
E
M
Y
G
V
D
L
H
P
V
Site 19
Y214
G
V
D
L
H
P
V
Y
G
E
N
K
S
E
Y
Site 20
S219
P
V
Y
G
E
N
K
S
E
Y
F
L
G
L
T
Site 21
Y221
Y
G
E
N
K
S
E
Y
F
L
G
L
T
P
V
Site 22
Y242
N
K
K
Q
V
G
K
Y
F
W
P
R
I
T
K
Site 23
S270
G
K
D
C
N
E
T
S
F
F
F
E
A
R
S
Site 24
S277
S
F
F
F
E
A
R
S
K
T
A
C
K
H
L
Site 25
T279
F
F
E
A
R
S
K
T
A
C
K
H
L
W
K
Site 26
S302
F
R
M
P
E
N
E
S
N
S
L
S
R
K
L
Site 27
S304
M
P
E
N
E
S
N
S
L
S
R
K
L
S
K
Site 28
S306
E
N
E
S
N
S
L
S
R
K
L
S
K
F
G
Site 29
S310
N
S
L
S
R
K
L
S
K
F
G
S
I
R
Y
Site 30
S314
R
K
L
S
K
F
G
S
I
R
Y
K
H
R
Y
Site 31
Y317
S
K
F
G
S
I
R
Y
K
H
R
Y
S
G
R
Site 32
Y321
S
I
R
Y
K
H
R
Y
S
G
R
T
A
L
Q
Site 33
S322
I
R
Y
K
H
R
Y
S
G
R
T
A
L
Q
M
Site 34
T325
K
H
R
Y
S
G
R
T
A
L
Q
M
S
R
D
Site 35
S334
L
Q
M
S
R
D
L
S
I
Q
L
P
R
P
D
Site 36
T345
P
R
P
D
Q
N
V
T
R
S
R
S
K
T
Y
Site 37
S347
P
D
Q
N
V
T
R
S
R
S
K
T
Y
P
K
Site 38
S349
Q
N
V
T
R
S
R
S
K
T
Y
P
K
R
I
Site 39
T351
V
T
R
S
R
S
K
T
Y
P
K
R
I
A
Q
Site 40
S364
A
Q
T
Q
P
A
E
S
N
T
I
S
R
I
T
Site 41
S368
P
A
E
S
N
T
I
S
R
I
T
A
N
M
E
Site 42
T371
S
N
T
I
S
R
I
T
A
N
M
E
N
G
E
Site 43
T382
E
N
G
E
N
E
G
T
I
K
I
I
A
P
S
Site 44
S389
T
I
K
I
I
A
P
S
P
V
K
S
F
K
K
Site 45
S393
I
A
P
S
P
V
K
S
F
K
K
A
K
N
E
Site 46
S402
K
K
A
K
N
E
N
S
P
D
T
Q
R
S
K
Site 47
T405
K
N
E
N
S
P
D
T
Q
R
S
K
S
L
M
Site 48
S408
N
S
P
D
T
Q
R
S
K
S
L
M
H
S
W
Site 49
S410
P
D
T
Q
R
S
K
S
L
M
H
S
W
E
E
Site 50
S414
R
S
K
S
L
M
H
S
W
E
E
N
G
P
Q
Site 51
S484
S
R
S
R
C
N
T
S
S
G
S
E
S
E
N
Site 52
S489
N
T
S
S
G
S
E
S
E
N
S
N
R
E
H
Site 53
S492
S
G
S
E
S
E
N
S
N
R
E
H
R
K
K
Site 54
S533
K
N
Q
A
D
P
N
S
R
R
S
R
H
R
S
Site 55
S536
A
D
P
N
S
R
R
S
R
H
R
S
R
S
R
Site 56
S540
S
R
R
S
R
H
R
S
R
S
R
S
P
D
I
Site 57
T590
Q
G
D
P
I
R
I
T
H
S
H
S
P
K
L
Site 58
S592
D
P
I
R
I
T
H
S
H
S
P
K
L
Y
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation