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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
XAB2
Full Name:
Pre-mRNA-splicing factor SYF1
Alias:
crn-related protein kim1; HCNP; HCRN; NTC90; SYF1; SYF1, RNA splicing factor; XPA binding protein 2; XPA-binding protein 2
Type:
Mass (Da):
100010
Number AA:
UniProt ID:
Q9HCS7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005654
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0006397
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
V
V
M
A
R
L
S
R
P
E
R
P
D
L
Site 2
Y24
F
E
E
E
D
L
P
Y
E
E
E
I
M
R
N
Site 3
Y41
S
V
K
C
W
L
R
Y
I
E
F
K
Q
G
A
Site 4
Y57
K
P
R
L
N
Q
L
Y
E
R
A
L
K
L
L
Site 5
Y74
S
Y
K
L
W
Y
R
Y
L
K
A
R
R
A
Q
Site 6
T88
Q
V
K
H
R
C
V
T
D
P
A
Y
E
D
V
Site 7
Y92
R
C
V
T
D
P
A
Y
E
D
V
N
N
C
H
Site 8
T127
L
M
D
Q
G
R
V
T
H
T
R
R
T
F
D
Site 9
T132
R
V
T
H
T
R
R
T
F
D
R
A
L
R
A
Site 10
T143
A
L
R
A
L
P
I
T
Q
H
S
R
I
W
P
Site 11
Y152
H
S
R
I
W
P
L
Y
L
R
F
L
R
S
H
Site 12
S158
L
Y
L
R
F
L
R
S
H
P
L
P
E
T
A
Site 13
T164
R
S
H
P
L
P
E
T
A
V
R
G
Y
R
R
Site 14
Y169
P
E
T
A
V
R
G
Y
R
R
F
L
K
L
S
Site 15
S176
Y
R
R
F
L
K
L
S
P
E
S
A
E
E
Y
Site 16
Y183
S
P
E
S
A
E
E
Y
I
E
Y
L
K
S
S
Site 17
Y186
S
A
E
E
Y
I
E
Y
L
K
S
S
D
R
L
Site 18
S189
E
Y
I
E
Y
L
K
S
S
D
R
L
D
E
A
Site 19
S190
Y
I
E
Y
L
K
S
S
D
R
L
D
E
A
A
Site 20
T202
E
A
A
Q
R
L
A
T
V
V
N
D
E
R
F
Site 21
S211
V
N
D
E
R
F
V
S
K
A
G
K
S
N
Y
Site 22
Y218
S
K
A
G
K
S
N
Y
Q
L
W
H
E
L
C
Site 23
S229
H
E
L
C
D
L
I
S
Q
N
P
D
K
V
Q
Site 24
T252
R
G
G
L
T
R
F
T
D
Q
L
G
K
L
W
Site 25
Y266
W
C
S
L
A
D
Y
Y
I
R
S
G
H
F
E
Site 26
Y279
F
E
K
A
R
D
V
Y
E
E
A
I
R
T
V
Site 27
S298
D
F
T
Q
V
F
D
S
Y
A
Q
F
E
E
S
Site 28
Y299
F
T
Q
V
F
D
S
Y
A
Q
F
E
E
S
M
Site 29
S305
S
Y
A
Q
F
E
E
S
M
I
A
A
K
M
E
Site 30
S339
A
R
F
E
Q
L
I
S
R
R
P
L
L
L
N
Site 31
S347
R
R
P
L
L
L
N
S
V
L
L
R
Q
N
P
Site 32
T377
R
P
R
E
I
I
N
T
Y
T
E
A
V
Q
T
Site 33
T384
T
Y
T
E
A
V
Q
T
V
D
P
F
K
A
T
Site 34
T396
K
A
T
G
K
P
H
T
L
W
V
A
F
A
K
Site 35
Y405
W
V
A
F
A
K
F
Y
E
D
N
G
Q
L
D
Site 36
Y449
L
E
L
R
H
E
N
Y
D
E
A
L
R
L
L
Site 37
T460
L
R
L
L
R
K
A
T
A
L
P
A
R
R
A
Site 38
Y469
L
P
A
R
R
A
E
Y
F
D
G
S
E
P
V
Site 39
S473
R
A
E
Y
F
D
G
S
E
P
V
Q
N
R
V
Site 40
Y481
E
P
V
Q
N
R
V
Y
K
S
L
K
V
W
S
Site 41
S496
M
L
A
D
L
E
E
S
L
G
T
F
Q
S
T
Site 42
T499
D
L
E
E
S
L
G
T
F
Q
S
T
K
A
V
Site 43
S502
E
S
L
G
T
F
Q
S
T
K
A
V
Y
D
R
Site 44
Y507
F
Q
S
T
K
A
V
Y
D
R
I
L
D
L
R
Site 45
Y533
M
F
L
E
E
H
K
Y
F
E
E
S
F
K
A
Site 46
S537
E
H
K
Y
F
E
E
S
F
K
A
Y
E
R
G
Site 47
Y541
F
E
E
S
F
K
A
Y
E
R
G
I
S
L
F
Site 48
S546
K
A
Y
E
R
G
I
S
L
F
K
W
P
N
V
Site 49
Y568
L
T
K
F
I
A
R
Y
G
G
R
K
L
E
R
Site 50
Y596
P
K
Y
A
K
T
L
Y
L
L
Y
A
Q
L
E
Site 51
Y599
A
K
T
L
Y
L
L
Y
A
Q
L
E
E
E
W
Site 52
Y616
A
R
H
A
M
A
V
Y
E
R
A
T
R
A
V
Site 53
T620
M
A
V
Y
E
R
A
T
R
A
V
E
P
A
Q
Site 54
Y635
Q
Y
D
M
F
N
I
Y
I
K
R
A
A
E
I
Site 55
Y643
I
K
R
A
A
E
I
Y
G
V
T
H
T
R
G
Site 56
S660
Q
K
A
I
E
V
L
S
D
E
H
A
R
E
M
Site 57
S729
E
M
L
R
I
R
R
S
V
Q
A
T
Y
N
T
Site 58
T733
I
R
R
S
V
Q
A
T
Y
N
T
Q
V
N
F
Site 59
Y734
R
R
S
V
Q
A
T
Y
N
T
Q
V
N
F
M
Site 60
T736
S
V
Q
A
T
Y
N
T
Q
V
N
F
M
A
S
Site 61
S751
Q
M
L
K
V
S
G
S
A
T
G
T
V
S
D
Site 62
S757
G
S
A
T
G
T
V
S
D
L
A
P
G
Q
S
Site 63
S764
S
D
L
A
P
G
Q
S
G
M
D
D
M
K
L
Site 64
S793
D
Q
P
L
R
A
Q
S
K
I
L
F
V
R
S
Site 65
S800
S
K
I
L
F
V
R
S
D
A
S
R
E
E
L
Site 66
S803
L
F
V
R
S
D
A
S
R
E
E
L
A
E
L
Site 67
S851
V
P
A
A
V
F
G
S
L
K
E
D
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation