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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BRMS1
Full Name:
Breast cancer metastasis-suppressor 1
Alias:
Type:
Mass (Da):
28443
Number AA:
246
UniProt ID:
Q9HCU9
International Prot ID:
IPI00607848
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0009987
GO:0045786
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
P
V
Q
P
P
S
K
D
T
E
E
M
E
Site 2
S19
E
M
E
A
E
G
D
S
A
A
E
M
N
G
E
Site 3
S30
M
N
G
E
E
E
E
S
E
E
E
R
S
G
S
Site 4
S35
E
E
S
E
E
E
R
S
G
S
Q
T
E
S
E
Site 5
S37
S
E
E
E
R
S
G
S
Q
T
E
S
E
E
E
Site 6
T39
E
E
R
S
G
S
Q
T
E
S
E
E
E
S
S
Site 7
S41
R
S
G
S
Q
T
E
S
E
E
E
S
S
E
M
Site 8
S45
Q
T
E
S
E
E
E
S
S
E
M
D
D
E
D
Site 9
S46
T
E
S
E
E
E
S
S
E
M
D
D
E
D
Y
Site 10
Y53
S
E
M
D
D
E
D
Y
E
R
R
R
S
E
C
Site 11
S58
E
D
Y
E
R
R
R
S
E
C
V
S
E
M
L
Site 12
S62
R
R
R
S
E
C
V
S
E
M
L
D
L
E
K
Site 13
S72
L
D
L
E
K
Q
F
S
E
L
K
E
K
L
F
Site 14
S84
K
L
F
R
E
R
L
S
Q
L
R
L
R
L
E
Site 15
Y101
G
A
E
R
A
P
E
Y
T
E
P
L
G
G
L
Site 16
T102
A
E
R
A
P
E
Y
T
E
P
L
G
G
L
Q
Site 17
Y134
L
D
V
I
R
N
K
Y
E
C
E
L
Q
G
A
Site 18
Y153
E
S
E
K
L
L
L
Y
D
T
L
Q
G
E
L
Site 19
T155
E
K
L
L
L
Y
D
T
L
Q
G
E
L
Q
E
Site 20
S173
R
L
E
E
D
R
Q
S
L
D
L
S
S
E
W
Site 21
S177
D
R
Q
S
L
D
L
S
S
E
W
W
D
D
K
Site 22
S178
R
Q
S
L
D
L
S
S
E
W
W
D
D
K
L
Site 23
S190
D
K
L
H
A
R
G
S
S
R
S
W
D
S
L
Site 24
S191
K
L
H
A
R
G
S
S
R
S
W
D
S
L
P
Site 25
S193
H
A
R
G
S
S
R
S
W
D
S
L
P
P
S
Site 26
S196
G
S
S
R
S
W
D
S
L
P
P
S
K
R
K
Site 27
S200
S
W
D
S
L
P
P
S
K
R
K
K
A
P
L
Site 28
S209
R
K
K
A
P
L
V
S
G
P
Y
I
V
Y
M
Site 29
S237
K
K
A
R
A
A
V
S
P
Q
K
R
K
S
D
Site 30
S243
V
S
P
Q
K
R
K
S
D
G
P
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation