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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIST
Full Name:
Golgi-associated PDZ and coiled-coil motif-containing protein
Alias:
CAL; CFTR-associated ligand; DJ94G16.2; FIG; Fused in glioblastoma; Golgi associated PDZ and coiled-coil motif containing; GOPC; GOPC1; PDZ protein interacting specifically with TC10; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10
Type:
Membrane protein, peripheral
Mass (Da):
50520
Number AA:
462
UniProt ID:
Q9HD26
International Prot ID:
IPI00186721
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0030425
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0042980
GO:0050430
PhosphoSite+
KinaseNET
Biological Process:
GO:0006888
GO:0006893
GO:0045176
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T63
D
P
D
Q
A
D
I
T
Y
E
G
R
Q
K
M
Site 2
Y64
P
D
Q
A
D
I
T
Y
E
G
R
Q
K
M
T
Site 3
S72
E
G
R
Q
K
M
T
S
L
S
S
C
F
A
Q
Site 4
S74
R
Q
K
M
T
S
L
S
S
C
F
A
Q
L
C
Site 5
S103
A
Q
L
V
D
L
K
S
E
L
T
E
T
Q
A
Site 6
T108
L
K
S
E
L
T
E
T
Q
A
E
K
V
V
L
Site 7
S128
D
Q
L
L
Q
L
H
S
I
Q
L
Q
L
H
A
Site 8
T145
G
Q
S
A
D
S
G
T
I
K
A
K
L
S
G
Site 9
S151
G
T
I
K
A
K
L
S
G
P
S
V
E
E
L
Site 10
Y201
A
V
L
Q
A
E
V
Y
G
A
R
L
A
A
K
Site 11
Y209
G
A
R
L
A
A
K
Y
L
D
K
E
L
A
G
Site 12
T251
I
H
L
H
R
H
K
T
V
I
R
A
C
R
G
Site 13
S276
P
P
G
H
D
Q
D
S
L
K
K
S
Q
G
V
Site 14
S280
D
Q
D
S
L
K
K
S
Q
G
V
G
P
I
R
Site 15
S302
D
H
E
G
L
G
I
S
I
T
G
G
K
E
H
Site 16
T304
E
G
L
G
I
S
I
T
G
G
K
E
H
G
V
Site 17
T347
N
G
V
N
L
R
D
T
K
H
K
E
A
V
T
Site 18
S357
K
E
A
V
T
I
L
S
Q
Q
R
G
E
I
E
Site 19
S376
Y
V
A
P
E
V
D
S
D
D
E
N
V
E
Y
Site 20
Y383
S
D
D
E
N
V
E
Y
E
D
E
S
G
H
R
Site 21
Y391
E
D
E
S
G
H
R
Y
R
L
Y
L
D
E
L
Site 22
Y394
S
G
H
R
Y
R
L
Y
L
D
E
L
E
G
G
Site 23
S407
G
G
G
N
P
G
A
S
C
K
D
T
S
G
E
Site 24
T411
P
G
A
S
C
K
D
T
S
G
E
I
K
V
L
Site 25
S412
G
A
S
C
K
D
T
S
G
E
I
K
V
L
Q
Site 26
T437
H
E
N
G
D
L
G
T
A
S
E
T
P
L
D
Site 27
S439
N
G
D
L
G
T
A
S
E
T
P
L
D
D
G
Site 28
T441
D
L
G
T
A
S
E
T
P
L
D
D
G
A
S
Site 29
S448
T
P
L
D
D
G
A
S
K
L
D
D
L
H
T
Site 30
T455
S
K
L
D
D
L
H
T
L
Y
H
K
K
S
Y
Site 31
Y457
L
D
D
L
H
T
L
Y
H
K
K
S
Y
_
_
Site 32
S461
H
T
L
Y
H
K
K
S
Y
_
_
_
_
_
_
Site 33
Y462
T
L
Y
H
K
K
S
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation