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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLA/LP
Full Name:
O-phosphoseryl-tRNA(Sec) selenium transferase
Alias:
Liver-pancreas antigen; Selenocysteine synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase; Sep-tRNA:Sec-tRNA synthase; Ser/Sec; SLA; SLA/LP autoantigen; SLA-p35; Soluble liver antigen; Soluble liver antigen/liver pancreas antigen; SPCS; TRNA(Ser/Sec)-associated antigenic protein; TRNP48; UGA suppressor tRNA-associated protein; UGTAP
Type:
RNA binding protein; Transferase; EC 2.9.1.-
Mass (Da):
55708
Number AA:
501
UniProt ID:
Q9HD40
International Prot ID:
IPI00155389
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008430
GO:0016786
GO:0000049
PhosphoSite+
KinaseNET
Biological Process:
GO:0001514
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
A
A
G
E
R
L
V
S
P
A
Y
V
R
Q
G
Site 2
Y17
E
R
L
V
S
P
A
Y
V
R
Q
G
C
E
A
Site 3
S27
Q
G
C
E
A
R
R
S
H
E
H
L
I
R
L
Site 4
S49
P
E
N
G
W
D
E
S
T
L
E
L
F
L
H
Site 5
T50
E
N
G
W
D
E
S
T
L
E
L
F
L
H
E
Site 6
S81
E
R
E
G
R
V
A
S
A
L
V
A
R
R
H
Site 7
S98
F
I
H
G
I
G
R
S
G
D
I
S
A
V
Q
Site 8
S102
I
G
R
S
G
D
I
S
A
V
Q
P
K
A
A
Site 9
T118
S
S
L
L
N
K
I
T
N
S
L
V
L
D
I
Site 10
S120
L
L
N
K
I
T
N
S
L
V
L
D
I
I
K
Site 11
T144
C
F
V
V
P
M
A
T
G
M
S
L
T
L
C
Site 12
T154
S
L
T
L
C
F
L
T
L
R
H
K
R
P
K
Site 13
Y164
H
K
R
P
K
A
K
Y
I
I
W
P
R
I
D
Site 14
Y255
P
H
I
V
N
N
A
Y
G
V
Q
S
S
K
C
Site 15
Y310
I
Q
E
I
S
K
M
Y
P
G
R
A
S
A
S
Site 16
S315
K
M
Y
P
G
R
A
S
A
S
P
S
L
D
V
Site 17
S317
Y
P
G
R
A
S
A
S
P
S
L
D
V
L
I
Site 18
T325
P
S
L
D
V
L
I
T
L
L
S
L
G
S
N
Site 19
S328
D
V
L
I
T
L
L
S
L
G
S
N
G
Y
K
Site 20
Y334
L
S
L
G
S
N
G
Y
K
K
L
L
K
E
R
Site 21
S346
K
E
R
K
E
M
F
S
Y
L
S
N
Q
I
K
Site 22
Y347
E
R
K
E
M
F
S
Y
L
S
N
Q
I
K
K
Site 23
S349
K
E
M
F
S
Y
L
S
N
Q
I
K
K
L
S
Site 24
T366
Y
N
E
R
L
L
H
T
P
H
N
P
I
S
L
Site 25
S372
H
T
P
H
N
P
I
S
L
A
M
T
L
K
T
Site 26
T376
N
P
I
S
L
A
M
T
L
K
T
L
D
E
H
Site 27
T379
S
L
A
M
T
L
K
T
L
D
E
H
R
D
K
Site 28
T389
E
H
R
D
K
A
V
T
Q
L
G
S
M
L
F
Site 29
T397
Q
L
G
S
M
L
F
T
R
Q
V
S
G
A
R
Site 30
S415
L
G
S
M
Q
T
V
S
G
Y
T
F
R
G
F
Site 31
Y417
S
M
Q
T
V
S
G
Y
T
F
R
G
F
M
S
Site 32
S466
K
A
V
R
K
E
R
S
K
E
S
D
D
N
Y
Site 33
Y473
S
K
E
S
D
D
N
Y
D
K
T
E
D
V
D
Site 34
T476
S
D
D
N
Y
D
K
T
E
D
V
D
I
E
E
Site 35
T495
L
D
N
V
L
L
D
T
Y
Q
D
A
S
S
_
Site 36
Y496
D
N
V
L
L
D
T
Y
Q
D
A
S
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation