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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERVK5
Full Name:
HERV-K_3q12.3 provirus ancestral Gag polyprotein
Alias:
Gag polyprotein; GAK8; HERV-K(II) Gag protein
Type:
Mass (Da):
73590
Number AA:
UniProt ID:
Q9HDB9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005886
GO:0019028
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0005198
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0016032
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
G
Q
T
K
S
K
T
K
S
K
Y
A
S
Y
Site 2
S10
Q
T
K
S
K
T
K
S
K
Y
A
S
Y
L
S
Site 3
Y12
K
S
K
T
K
S
K
Y
A
S
Y
L
S
F
I
Site 4
S14
K
T
K
S
K
Y
A
S
Y
L
S
F
I
K
I
Site 5
S31
K
R
G
G
V
R
V
S
T
K
N
L
I
K
L
Site 6
T32
R
G
G
V
R
V
S
T
K
N
L
I
K
L
F
Site 7
T97
A
A
L
E
P
F
Q
T
K
E
D
S
V
S
V
Site 8
S101
P
F
Q
T
K
E
D
S
V
S
V
S
D
A
P
Site 9
S103
Q
T
K
E
D
S
V
S
V
S
D
A
P
G
S
Site 10
S105
K
E
D
S
V
S
V
S
D
A
P
G
S
C
V
Site 11
S110
S
V
S
D
A
P
G
S
C
V
I
D
C
N
E
Site 12
T119
V
I
D
C
N
E
K
T
G
R
K
S
Q
K
E
Site 13
S123
N
E
K
T
G
R
K
S
Q
K
E
T
E
S
L
Site 14
T127
G
R
K
S
Q
K
E
T
E
S
L
H
C
E
Y
Site 15
S129
K
S
Q
K
E
T
E
S
L
H
C
E
Y
V
T
Site 16
Y134
T
E
S
L
H
C
E
Y
V
T
E
P
V
M
A
Site 17
Y149
Q
S
T
Q
N
V
D
Y
N
Q
L
Q
G
V
I
Site 18
Y157
N
Q
L
Q
G
V
I
Y
P
E
T
L
K
L
E
Site 19
T160
Q
G
V
I
Y
P
E
T
L
K
L
E
G
K
G
Site 20
S174
G
P
E
L
V
G
P
S
E
S
K
P
R
G
P
Site 21
S176
E
L
V
G
P
S
E
S
K
P
R
G
P
S
P
Site 22
S182
E
S
K
P
R
G
P
S
P
L
P
A
G
Q
V
Site 23
T192
P
A
G
Q
V
P
V
T
L
Q
P
Q
T
Q
V
Site 24
T204
T
Q
V
K
E
N
K
T
Q
P
P
V
A
Y
Q
Site 25
Y212
Q
P
P
V
A
Y
Q
Y
W
P
P
A
E
L
Q
Site 26
Y220
W
P
P
A
E
L
Q
Y
L
P
P
P
E
S
Q
Site 27
S226
Q
Y
L
P
P
P
E
S
Q
Y
G
Y
P
G
M
Site 28
Y228
L
P
P
P
E
S
Q
Y
G
Y
P
G
M
P
P
Site 29
Y230
P
P
E
S
Q
Y
G
Y
P
G
M
P
P
A
L
Site 30
Y243
A
L
Q
G
R
A
P
Y
P
Q
P
P
T
V
R
Site 31
T248
A
P
Y
P
Q
P
P
T
V
R
L
N
P
T
A
Site 32
T254
P
T
V
R
L
N
P
T
A
S
R
S
G
Q
G
Site 33
S256
V
R
L
N
P
T
A
S
R
S
G
Q
G
G
T
Site 34
S258
L
N
P
T
A
S
R
S
G
Q
G
G
T
L
H
Site 35
T305
G
A
P
A
R
A
E
T
R
C
E
P
F
T
M
Site 36
T311
E
T
R
C
E
P
F
T
M
K
M
L
K
D
I
Site 37
Y325
I
K
E
G
V
K
Q
Y
G
S
N
S
P
Y
I
Site 38
S327
E
G
V
K
Q
Y
G
S
N
S
P
Y
I
R
T
Site 39
S329
V
K
Q
Y
G
S
N
S
P
Y
I
R
T
L
L
Site 40
Y331
Q
Y
G
S
N
S
P
Y
I
R
T
L
L
D
S
Site 41
T334
S
N
S
P
Y
I
R
T
L
L
D
S
I
A
H
Site 42
S338
Y
I
R
T
L
L
D
S
I
A
H
G
N
R
L
Site 43
T346
I
A
H
G
N
R
L
T
P
Y
D
W
E
S
L
Site 44
Y348
H
G
N
R
L
T
P
Y
D
W
E
S
L
A
K
Site 45
S352
L
T
P
Y
D
W
E
S
L
A
K
S
S
L
S
Site 46
S356
D
W
E
S
L
A
K
S
S
L
S
S
S
Q
Y
Site 47
S357
W
E
S
L
A
K
S
S
L
S
S
S
Q
Y
L
Site 48
S359
S
L
A
K
S
S
L
S
S
S
Q
Y
L
Q
F
Site 49
S360
L
A
K
S
S
L
S
S
S
Q
Y
L
Q
F
K
Site 50
S361
A
K
S
S
L
S
S
S
Q
Y
L
Q
F
K
T
Site 51
Y363
S
S
L
S
S
S
Q
Y
L
Q
F
K
T
W
W
Site 52
T384
Q
V
R
K
N
Q
A
T
K
P
T
V
N
I
D
Site 53
S403
L
G
T
G
P
N
W
S
T
I
N
Q
Q
S
V
Site 54
T435
G
K
I
Q
D
P
G
T
A
F
P
I
N
S
I
Site 55
S441
G
T
A
F
P
I
N
S
I
R
Q
G
S
K
E
Site 56
S446
I
N
S
I
R
Q
G
S
K
E
P
Y
P
D
F
Site 57
Y450
R
Q
G
S
K
E
P
Y
P
D
F
V
A
R
L
Site 58
S464
L
Q
D
A
A
Q
K
S
I
T
D
D
N
A
R
Site 59
T533
A
Q
A
M
R
G
L
T
L
G
G
Q
V
R
T
Site 60
T540
T
L
G
G
Q
V
R
T
F
G
K
K
C
Y
N
Site 61
Y546
R
T
F
G
K
K
C
Y
N
C
G
Q
I
G
H
Site 62
S557
Q
I
G
H
L
K
R
S
C
P
V
L
N
K
Q
Site 63
S607
D
K
D
G
Q
P
L
S
G
N
R
K
R
G
Q
Site 64
S650
I
P
P
L
Q
G
V
S
Q
L
Q
Q
S
N
S
Site 65
S655
G
V
S
Q
L
Q
Q
S
N
S
C
P
A
P
Q
Site 66
S657
S
Q
L
Q
Q
S
N
S
C
P
A
P
Q
Q
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation