KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
JPH1
Full Name:
Junctophilin-1
Alias:
JP1; JP-1; Junctophilin 1; Junctophilin type 1; Junctophilin type1; Mitsugumin72
Type:
Endoplasmic reticulum
Mass (Da):
71686
Number AA:
661
UniProt ID:
Q9HDC5
International Prot ID:
IPI00173461
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0019898
GO:0016021
GO:0030314
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0060402
GO:0060314
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
D
F
D
D
G
G
T
Y
C
G
G
W
E
E
G
Site 2
Y38
G
P
K
G
Q
G
E
Y
S
G
S
W
S
H
G
Site 3
S39
P
K
G
Q
G
E
Y
S
G
S
W
S
H
G
F
Site 4
S41
G
Q
G
E
Y
S
G
S
W
S
H
G
F
E
V
Site 5
S43
G
E
Y
S
G
S
W
S
H
G
F
E
V
V
G
Site 6
Y52
G
F
E
V
V
G
G
Y
T
W
P
S
G
N
T
Site 7
Y60
T
W
P
S
G
N
T
Y
Q
G
Y
W
A
Q
G
Site 8
Y63
S
G
N
T
Y
Q
G
Y
W
A
Q
G
K
R
H
Site 9
Y94
S
H
G
F
K
G
R
Y
G
V
R
Q
S
L
C
Site 10
S99
G
R
Y
G
V
R
Q
S
L
C
T
P
A
R
Y
Site 11
T102
G
V
R
Q
S
L
C
T
P
A
R
Y
E
G
T
Site 12
Y106
S
L
C
T
P
A
R
Y
E
G
T
W
S
N
G
Site 13
Y118
S
N
G
L
Q
D
G
Y
G
V
E
T
Y
G
D
Site 14
Y123
D
G
Y
G
V
E
T
Y
G
D
G
G
T
Y
Q
Site 15
T128
E
T
Y
G
D
G
G
T
Y
Q
G
Q
W
A
G
Site 16
Y129
T
Y
G
D
G
G
T
Y
Q
G
Q
W
A
G
G
Site 17
Y141
A
G
G
M
R
H
G
Y
G
V
R
Q
S
V
P
Site 18
S146
H
G
Y
G
V
R
Q
S
V
P
Y
G
M
A
T
Site 19
S157
G
M
A
T
V
I
R
S
P
L
R
T
S
L
A
Site 20
T161
V
I
R
S
P
L
R
T
S
L
A
S
L
R
S
Site 21
S162
I
R
S
P
L
R
T
S
L
A
S
L
R
S
E
Site 22
S165
P
L
R
T
S
L
A
S
L
R
S
E
Q
S
N
Site 23
S168
T
S
L
A
S
L
R
S
E
Q
S
N
G
S
V
Site 24
S171
A
S
L
R
S
E
Q
S
N
G
S
V
L
H
D
Site 25
S185
D
A
A
A
A
A
D
S
P
A
G
T
R
G
G
Site 26
T189
A
A
D
S
P
A
G
T
R
G
G
F
V
L
N
Site 27
S216
G
G
L
F
R
R
G
S
L
L
G
S
M
K
L
Site 28
S220
R
R
G
S
L
L
G
S
M
K
L
R
K
S
E
Site 29
S226
G
S
M
K
L
R
K
S
E
S
K
S
S
I
S
Site 30
S228
M
K
L
R
K
S
E
S
K
S
S
I
S
S
K
Site 31
S230
L
R
K
S
E
S
K
S
S
I
S
S
K
R
S
Site 32
S231
R
K
S
E
S
K
S
S
I
S
S
K
R
S
S
Site 33
S233
S
E
S
K
S
S
I
S
S
K
R
S
S
V
R
Site 34
S234
E
S
K
S
S
I
S
S
K
R
S
S
V
R
S
Site 35
S237
S
S
I
S
S
K
R
S
S
V
R
S
D
A
A
Site 36
S238
S
I
S
S
K
R
S
S
V
R
S
D
A
A
M
Site 37
S241
S
K
R
S
S
V
R
S
D
A
A
M
S
R
I
Site 38
S246
V
R
S
D
A
A
M
S
R
I
S
S
S
D
A
Site 39
S249
D
A
A
M
S
R
I
S
S
S
D
A
N
S
T
Site 40
S250
A
A
M
S
R
I
S
S
S
D
A
N
S
T
I
Site 41
S251
A
M
S
R
I
S
S
S
D
A
N
S
T
I
S
Site 42
S255
I
S
S
S
D
A
N
S
T
I
S
F
G
D
V
Site 43
S258
S
D
A
N
S
T
I
S
F
G
D
V
D
C
D
Site 44
T276
V
E
D
H
V
D
A
T
T
T
E
T
Y
M
G
Site 45
S296
K
R
N
G
F
G
V
S
E
R
S
N
G
M
K
Site 46
S299
G
F
G
V
S
E
R
S
N
G
M
K
Y
E
G
Site 47
Y304
E
R
S
N
G
M
K
Y
E
G
E
W
A
N
N
Site 48
Y316
A
N
N
K
R
H
G
Y
G
C
T
V
F
P
D
Site 49
T319
K
R
H
G
Y
G
C
T
V
F
P
D
G
S
K
Site 50
S325
C
T
V
F
P
D
G
S
K
E
E
G
K
Y
K
Site 51
Y331
G
S
K
E
E
G
K
Y
K
N
N
I
L
V
R
Site 52
T350
Q
L
I
P
I
R
H
T
K
T
R
E
K
V
D
Site 53
S413
R
A
V
A
R
E
L
S
P
D
F
Y
Q
P
G
Site 54
Y417
R
E
L
S
P
D
F
Y
Q
P
G
P
D
Y
V
Site 55
Y423
F
Y
Q
P
G
P
D
Y
V
K
Q
R
F
Q
E
Site 56
T448
K
V
P
E
K
P
P
T
P
K
E
S
P
H
F
Site 57
S452
K
P
P
T
P
K
E
S
P
H
F
Y
R
K
G
Site 58
Y456
P
K
E
S
P
H
F
Y
R
K
G
T
T
P
P
Site 59
T460
P
H
F
Y
R
K
G
T
T
P
P
R
S
P
E
Site 60
T461
H
F
Y
R
K
G
T
T
P
P
R
S
P
E
A
Site 61
S465
K
G
T
T
P
P
R
S
P
E
A
S
P
K
H
Site 62
S469
P
P
R
S
P
E
A
S
P
K
H
S
H
S
P
Site 63
S473
P
E
A
S
P
K
H
S
H
S
P
A
S
S
P
Site 64
S475
A
S
P
K
H
S
H
S
P
A
S
S
P
K
P
Site 65
S478
K
H
S
H
S
P
A
S
S
P
K
P
L
K
K
Site 66
S479
H
S
H
S
P
A
S
S
P
K
P
L
K
K
Q
Site 67
S490
L
K
K
Q
N
P
S
S
G
A
R
L
N
Q
D
Site 68
S500
R
L
N
Q
D
K
R
S
V
A
D
E
Q
V
T
Site 69
S530
A
G
A
V
V
P
Q
S
K
Y
S
G
R
H
H
Site 70
Y532
A
V
V
P
Q
S
K
Y
S
G
R
H
H
I
P
Site 71
S533
V
V
P
Q
S
K
Y
S
G
R
H
H
I
P
N
Site 72
S542
R
H
H
I
P
N
P
S
N
G
E
L
H
S
Q
Site 73
S548
P
S
N
G
E
L
H
S
Q
Y
H
G
Y
Y
V
Site 74
Y550
N
G
E
L
H
S
Q
Y
H
G
Y
Y
V
K
L
Site 75
Y553
L
H
S
Q
Y
H
G
Y
Y
V
K
L
N
A
P
Site 76
Y554
H
S
Q
Y
H
G
Y
Y
V
K
L
N
A
P
Q
Site 77
S573
D
V
E
D
G
D
G
S
S
Q
S
S
S
A
L
Site 78
S574
V
E
D
G
D
G
S
S
Q
S
S
S
A
L
V
Site 79
S576
D
G
D
G
S
S
Q
S
S
S
A
L
V
H
K
Site 80
S577
G
D
G
S
S
Q
S
S
S
A
L
V
H
K
P
Site 81
S578
D
G
S
S
Q
S
S
S
A
L
V
H
K
P
S
Site 82
S585
S
A
L
V
H
K
P
S
A
N
K
W
S
P
S
Site 83
S590
K
P
S
A
N
K
W
S
P
S
K
S
V
T
K
Site 84
S592
S
A
N
K
W
S
P
S
K
S
V
T
K
P
V
Site 85
S594
N
K
W
S
P
S
K
S
V
T
K
P
V
A
K
Site 86
T596
W
S
P
S
K
S
V
T
K
P
V
A
K
E
S
Site 87
S622
A
I
P
K
N
P
A
S
N
D
S
C
P
A
L
Site 88
S635
A
L
E
K
E
A
N
S
G
P
N
S
I
M
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation