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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TUFT1
Full Name:
Tuftelin
Alias:
Type:
Mass (Da):
44264
Number AA:
390
UniProt ID:
Q9NNX1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T35
L
T
L
Q
G
E
L
T
G
D
E
L
E
H
I
Site 2
T50
A
Q
K
A
G
R
K
T
Y
A
M
V
S
S
H
Site 3
Y51
Q
K
A
G
R
K
T
Y
A
M
V
S
S
H
S
Site 4
S55
R
K
T
Y
A
M
V
S
S
H
S
A
G
H
S
Site 5
S56
K
T
Y
A
M
V
S
S
H
S
A
G
H
S
L
Site 6
S58
Y
A
M
V
S
S
H
S
A
G
H
S
L
A
S
Site 7
S62
S
S
H
S
A
G
H
S
L
A
S
E
L
V
E
Site 8
S65
S
A
G
H
S
L
A
S
E
L
V
E
S
H
D
Site 9
S70
L
A
S
E
L
V
E
S
H
D
G
H
E
E
I
Site 10
Y81
H
E
E
I
I
K
V
Y
L
K
G
R
S
G
D
Site 11
S101
K
N
I
N
Q
L
K
S
E
V
Q
Y
I
Q
E
Site 12
Y105
Q
L
K
S
E
V
Q
Y
I
Q
E
A
R
N
C
Site 13
S121
Q
K
L
R
E
D
I
S
S
K
L
D
R
N
L
Site 14
S122
K
L
R
E
D
I
S
S
K
L
D
R
N
L
G
Site 15
S131
L
D
R
N
L
G
D
S
L
H
R
Q
E
I
Q
Site 16
S148
L
E
K
P
N
G
F
S
Q
S
P
T
A
L
Y
Site 17
S150
K
P
N
G
F
S
Q
S
P
T
A
L
Y
S
S
Site 18
T152
N
G
F
S
Q
S
P
T
A
L
Y
S
S
P
P
Site 19
Y155
S
Q
S
P
T
A
L
Y
S
S
P
P
E
V
D
Site 20
S156
Q
S
P
T
A
L
Y
S
S
P
P
E
V
D
T
Site 21
S157
S
P
T
A
L
Y
S
S
P
P
E
V
D
T
C
Site 22
T163
S
S
P
P
E
V
D
T
C
I
N
E
D
V
E
Site 23
S171
C
I
N
E
D
V
E
S
L
R
K
T
V
Q
D
Site 24
T175
D
V
E
S
L
R
K
T
V
Q
D
L
L
A
K
Site 25
S192
E
A
K
R
Q
H
Q
S
D
C
V
A
F
E
V
Site 26
S202
V
A
F
E
V
T
L
S
R
Y
Q
R
E
A
E
Site 27
Y204
F
E
V
T
L
S
R
Y
Q
R
E
A
E
Q
S
Site 28
S211
Y
Q
R
E
A
E
Q
S
N
V
A
L
Q
R
E
Site 29
S262
V
A
L
E
E
L
R
S
N
N
A
D
C
Q
A
Site 30
T276
A
E
R
E
K
A
A
T
L
E
K
E
V
A
G
Site 31
S297
H
L
D
D
M
L
K
S
Q
Q
R
K
V
R
Q
Site 32
S312
M
I
E
Q
L
Q
N
S
K
A
V
I
Q
S
K
Site 33
T322
V
I
Q
S
K
D
A
T
I
Q
E
L
K
E
K
Site 34
Y332
E
L
K
E
K
I
A
Y
L
E
A
E
N
L
E
Site 35
S353
H
L
I
E
K
Q
I
S
H
G
N
F
S
T
Q
Site 36
T365
S
T
Q
A
R
A
K
T
E
N
P
G
S
I
R
Site 37
S370
A
K
T
E
N
P
G
S
I
R
I
S
K
P
P
Site 38
S374
N
P
G
S
I
R
I
S
K
P
P
S
P
K
P
Site 39
S378
I
R
I
S
K
P
P
S
P
K
P
M
P
V
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation