PhosphoNET

           
Protein Info 
   
Short Name:  PDE7B
Full Name:  cAMP-specific 3',5'-cyclic phosphodiesterase 7B
Alias:  cAMP-specific 3',5'-cyclic phosphodiesterase 7B; EC 3.1.4.17
Type:  Nucleotide Metabolism group, Purine metabolism family
Mass (Da):  51835
Number AA:  450
UniProt ID:  Q9NP56
International Prot ID:  IPI00014552
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0004115     PhosphoSite+ KinaseNET
Biological Process:  GO:0007165  GO:0007268   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T36DIRLRGQTGVRAERR
Site 2S45VRAERRGSYPFIDFR
Site 3Y46RAERRGSYPFIDFRL
Site 4S56IDFRLLNSTTYSGEI
Site 5T57DFRLLNSTTYSGEIG
Site 6T58FRLLNSTTYSGEIGT
Site 7Y59RLLNSTTYSGEIGTK
Site 8S60LLNSTTYSGEIGTKK
Site 9S74KKVKRLLSFQRYFHA
Site 10Y78RLLSFQRYFHASRLL
Site 11Y101LHLLDEDYLGQARHM
Site 12S130DRLTNGNSLVTLLCH
Site 13Y166LVMVQEDYHSQNPYH
Site 14Y172DYHSQNPYHNAVHAA
Site 15T228NQPFLIKTNHHLANL
Site 16Y236NHHLANLYQNMSVLE
Site 17T250ENHHWRSTIGMLRES
Site 18T268AHLPKEMTQDIEQQL
Site 19T282LGSLILATDINRQNE
Site 20S360QKFELEISPLCNQQK
Site 21S369LCNQQKDSIPSIQIG
Site 22T397AHFTGNSTLSENMLG
Site 23S399FTGNSTLSENMLGHL
Site 24S415HNKAQWKSLLPRQHR
Site 25S423LLPRQHRSRGSSGSG
Site 26S426RQHRSRGSSGSGPDH
Site 27S427QHRSRGSSGSGPDHD
Site 28S429RSRGSSGSGPDHDHA
Site 29S449SEEQEGDSP______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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