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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IL1RAPL2
Full Name:
X-linked interleukin-1 receptor accessory protein-like 2
Alias:
IL-1 receptor; IL-1 receptor accessory protein-like 2; IL1R9; IL-1R9; IL1RAPL-2; IL1RAPL-2-related; Interleukin 1 receptor accessory protein-like 2; Interleukin-1 receptor 9; IRPL2; Three immunoglobulin domain-containing IL-1 receptor-related 1; TI; TIGIRR-1; X-linked interleukin-1 receptor accessory protein-like 2
Type:
Receptor, cytokine
Mass (Da):
78670
Number AA:
686
UniProt ID:
Q9NP60
International Prot ID:
IPI00010099
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004910
PhosphoSite+
KinaseNET
Biological Process:
GO:0007417
GO:0045087
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T122
T
C
V
L
R
N
S
T
Y
C
M
K
V
S
M
Site 2
S343
R
N
G
R
K
H
A
S
V
L
L
R
K
K
D
Site 3
Y353
L
R
K
K
D
L
I
Y
K
I
E
L
A
G
G
Site 4
Y386
N
I
E
L
M
L
F
Y
R
Q
H
F
G
A
D
Site 5
T395
Q
H
F
G
A
D
E
T
N
D
D
N
K
E
Y
Site 6
Y402
T
N
D
D
N
K
E
Y
D
A
Y
L
S
Y
T
Site 7
Y405
D
N
K
E
Y
D
A
Y
L
S
Y
T
K
V
D
Site 8
S407
K
E
Y
D
A
Y
L
S
Y
T
K
V
D
Q
D
Site 9
T415
Y
T
K
V
D
Q
D
T
L
D
C
D
N
P
E
Site 10
S453
P
E
R
D
L
I
P
S
G
T
Y
M
E
D
L
Site 11
T455
R
D
L
I
P
S
G
T
Y
M
E
D
L
T
R
Site 12
T461
G
T
Y
M
E
D
L
T
R
Y
V
E
Q
S
R
Site 13
Y463
Y
M
E
D
L
T
R
Y
V
E
Q
S
R
R
L
Site 14
S485
Y
I
L
R
R
G
W
S
I
F
E
L
E
S
R
Site 15
S523
V
N
C
Q
E
V
E
S
L
K
R
S
I
K
L
Site 16
S532
K
R
S
I
K
L
L
S
L
I
K
W
K
G
S
Site 17
S539
S
L
I
K
W
K
G
S
K
S
S
K
L
N
S
Site 18
S541
I
K
W
K
G
S
K
S
S
K
L
N
S
K
F
Site 19
S542
K
W
K
G
S
K
S
S
K
L
N
S
K
F
W
Site 20
S546
S
K
S
S
K
L
N
S
K
F
W
K
H
L
V
Site 21
Y554
K
F
W
K
H
L
V
Y
E
M
P
I
K
K
K
Site 22
S572
P
R
C
H
V
L
D
S
A
E
Q
G
L
F
G
Site 23
S586
G
E
L
Q
P
I
P
S
I
A
M
T
S
T
S
Site 24
T595
A
M
T
S
T
S
A
T
L
V
S
S
Q
A
D
Site 25
S599
T
S
A
T
L
V
S
S
Q
A
D
L
P
E
F
Site 26
S609
D
L
P
E
F
H
P
S
D
S
M
Q
I
R
H
Site 27
T628
Y
K
H
E
I
P
A
T
T
L
P
V
P
S
L
Site 28
T640
P
S
L
G
N
H
H
T
Y
C
N
L
P
L
T
Site 29
Y641
S
L
G
N
H
H
T
Y
C
N
L
P
L
T
L
Site 30
T658
G
Q
L
P
L
N
N
T
L
K
D
T
Q
E
F
Site 31
T662
L
N
N
T
L
K
D
T
Q
E
F
H
R
N
S
Site 32
S669
T
Q
E
F
H
R
N
S
S
L
L
P
L
S
S
Site 33
S670
Q
E
F
H
R
N
S
S
L
L
P
L
S
S
K
Site 34
S675
N
S
S
L
L
P
L
S
S
K
E
L
S
F
T
Site 35
S676
S
S
L
L
P
L
S
S
K
E
L
S
F
T
S
Site 36
S680
P
L
S
S
K
E
L
S
F
T
S
D
I
W
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation