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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Gde5
Full Name:
Putative glycerophosphocholine phosphodiesterase GPCPD1
Alias:
KIAA1434
Type:
EC 3.1.-.-; Phosphodiesterase
Mass (Da):
76035
Number AA:
672
UniProt ID:
Q9NPB8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0030246
GO:0008889
PhosphoSite+
KinaseNET
Biological Process:
GO:0006071
GO:0006629
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T46
A
L
L
P
E
N
D
T
G
E
S
M
L
W
K
Site 2
Y66
S
R
G
V
S
V
Q
Y
R
Y
F
K
G
Y
F
Site 3
Y68
G
V
S
V
Q
Y
R
Y
F
K
G
Y
F
L
E
Site 4
Y72
Q
Y
R
Y
F
K
G
Y
F
L
E
P
K
T
I
Site 5
T78
G
Y
F
L
E
P
K
T
I
G
G
P
C
Q
V
Site 6
S98
E
T
H
L
Q
P
R
S
I
T
P
L
E
S
E
Site 7
T100
H
L
Q
P
R
S
I
T
P
L
E
S
E
I
I
Site 8
T128
T
L
D
S
G
W
L
T
C
Q
T
E
I
R
L
Site 9
Y139
E
I
R
L
R
L
H
Y
S
E
K
P
P
V
S
Site 10
S140
I
R
L
R
L
H
Y
S
E
K
P
P
V
S
I
Site 11
S146
Y
S
E
K
P
P
V
S
I
T
K
K
K
L
K
Site 12
S155
T
K
K
K
L
K
K
S
R
F
R
V
K
L
T
Site 13
T162
S
R
F
R
V
K
L
T
L
E
G
L
E
E
D
Site 14
S175
E
D
D
D
D
R
V
S
P
T
V
L
H
K
M
Site 15
S189
M
S
N
S
L
E
I
S
L
I
S
D
N
E
F
Site 16
S192
S
L
E
I
S
L
I
S
D
N
E
F
K
C
R
Site 17
S239
D
F
F
E
E
D
L
S
E
H
V
V
Q
G
D
Site 18
S281
L
P
I
M
S
R
N
S
R
K
T
I
G
K
V
Site 19
T284
M
S
R
N
S
R
K
T
I
G
K
V
R
V
D
Site 20
Y301
I
I
K
P
L
P
G
Y
S
C
D
M
K
S
S
Site 21
S302
I
K
P
L
P
G
Y
S
C
D
M
K
S
S
F
Site 22
Y312
M
K
S
S
F
S
K
Y
W
K
P
R
I
P
L
Site 23
S329
G
H
R
G
A
G
N
S
T
T
T
A
Q
L
A
Site 24
S345
V
Q
E
N
T
I
A
S
L
R
N
A
A
S
H
Site 25
S418
T
H
V
T
A
L
K
S
K
D
R
K
E
S
V
Site 26
S424
K
S
K
D
R
K
E
S
V
V
Q
E
E
N
S
Site 27
S431
S
V
V
Q
E
E
N
S
F
S
E
N
Q
P
F
Site 28
S433
V
Q
E
E
N
S
F
S
E
N
Q
P
F
P
S
Site 29
S440
S
E
N
Q
P
F
P
S
L
K
M
V
L
E
S
Site 30
Y476
W
D
G
N
L
S
T
Y
F
D
M
N
L
F
L
Site 31
S494
L
K
T
V
L
E
N
S
G
K
R
R
I
V
F
Site 32
S502
G
K
R
R
I
V
F
S
S
F
D
A
D
I
C
Site 33
S503
K
R
R
I
V
F
S
S
F
D
A
D
I
C
T
Site 34
Y519
V
R
Q
K
Q
N
K
Y
P
I
L
F
L
T
Q
Site 35
T525
K
Y
P
I
L
F
L
T
Q
G
K
S
E
I
Y
Site 36
Y532
T
Q
G
K
S
E
I
Y
P
E
L
M
D
L
R
Site 37
S540
P
E
L
M
D
L
R
S
R
T
T
P
I
A
M
Site 38
T543
M
D
L
R
S
R
T
T
P
I
A
M
S
F
A
Site 39
S548
R
T
T
P
I
A
M
S
F
A
Q
F
E
N
L
Site 40
S570
E
D
L
L
R
N
P
S
Y
I
Q
E
A
K
A
Site 41
Y571
D
L
L
R
N
P
S
Y
I
Q
E
A
K
A
K
Site 42
Y608
L
G
V
N
G
L
I
Y
D
R
I
Y
D
W
M
Site 43
Y612
G
L
I
Y
D
R
I
Y
D
W
M
P
E
Q
P
Site 44
S639
Q
E
L
P
E
L
K
S
C
L
C
P
T
V
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation