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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPAG4
Full Name:
Sperm-associated antigen 4 protein
Alias:
Outer dense fiber-associated protein SPAG4;SUN domain-containing protein 4
Type:
Mass (Da):
48165
Number AA:
437
UniProt ID:
Q9NPE6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
R
R
S
S
R
P
G
S
A
S
S
Site 2
S9
R
R
S
S
R
P
G
S
A
S
S
S
R
K
H
Site 3
S11
S
S
R
P
G
S
A
S
S
S
R
K
H
T
P
Site 4
S12
S
R
P
G
S
A
S
S
S
R
K
H
T
P
N
Site 5
S13
R
P
G
S
A
S
S
S
R
K
H
T
P
N
F
Site 6
T17
A
S
S
S
R
K
H
T
P
N
F
F
S
E
N
Site 7
S22
K
H
T
P
N
F
F
S
E
N
S
S
M
S
I
Site 8
S25
P
N
F
F
S
E
N
S
S
M
S
I
T
S
E
Site 9
S26
N
F
F
S
E
N
S
S
M
S
I
T
S
E
D
Site 10
S28
F
S
E
N
S
S
M
S
I
T
S
E
D
S
K
Site 11
T30
E
N
S
S
M
S
I
T
S
E
D
S
K
G
L
Site 12
S31
N
S
S
M
S
I
T
S
E
D
S
K
G
L
R
Site 13
S34
M
S
I
T
S
E
D
S
K
G
L
R
S
A
E
Site 14
S39
E
D
S
K
G
L
R
S
A
E
P
G
P
G
E
Site 15
S56
G
R
R
A
R
G
P
S
C
G
E
P
A
L
S
Site 16
T71
A
G
V
P
G
G
T
T
W
A
G
S
S
Q
Q
Site 17
S75
G
G
T
T
W
A
G
S
S
Q
Q
K
P
A
P
Site 18
S76
G
T
T
W
A
G
S
S
Q
Q
K
P
A
P
R
Site 19
T95
Q
T
A
C
G
A
A
T
V
R
G
G
A
S
E
Site 20
S101
A
T
V
R
G
G
A
S
E
P
T
G
S
P
V
Site 21
T104
R
G
G
A
S
E
P
T
G
S
P
V
V
S
E
Site 22
S106
G
A
S
E
P
T
G
S
P
V
V
S
E
E
P
Site 23
S110
P
T
G
S
P
V
V
S
E
E
P
L
D
L
L
Site 24
T119
E
P
L
D
L
L
P
T
L
D
L
R
Q
E
M
Site 25
T201
N
E
P
K
E
M
L
T
L
S
E
Y
H
E
R
Site 26
S203
P
K
E
M
L
T
L
S
E
Y
H
E
R
V
R
Site 27
Y205
E
M
L
T
L
S
E
Y
H
E
R
V
R
S
Q
Site 28
S211
E
Y
H
E
R
V
R
S
Q
G
Q
Q
L
Q
Q
Site 29
S231
D
K
L
H
K
E
V
S
T
V
R
A
A
N
S
Site 30
T232
K
L
H
K
E
V
S
T
V
R
A
A
N
S
E
Site 31
S238
S
T
V
R
A
A
N
S
E
R
V
A
K
L
V
Site 32
Y259
D
F
V
R
K
P
D
Y
A
L
S
S
V
G
A
Site 33
S262
R
K
P
D
Y
A
L
S
S
V
G
A
S
I
D
Site 34
Y277
L
Q
K
T
S
H
D
Y
A
D
R
N
T
A
Y
Site 35
Y284
Y
A
D
R
N
T
A
Y
F
W
N
R
F
S
F
Site 36
Y294
N
R
F
S
F
W
N
Y
A
R
P
P
T
V
I
Site 37
T299
W
N
Y
A
R
P
P
T
V
I
L
E
P
H
V
Site 38
S332
L
P
G
R
V
Q
L
S
D
I
T
L
Q
H
P
Site 39
T335
R
V
Q
L
S
D
I
T
L
Q
H
P
P
P
S
Site 40
S342
T
L
Q
H
P
P
P
S
V
E
H
T
G
G
A
Site 41
T346
P
P
P
S
V
E
H
T
G
G
A
N
S
A
P
Site 42
S351
E
H
T
G
G
A
N
S
A
P
R
D
F
A
V
Site 43
T367
G
L
Q
V
Y
D
E
T
E
V
S
L
G
K
F
Site 44
S370
V
Y
D
E
T
E
V
S
L
G
K
F
T
F
D
Site 45
T375
E
V
S
L
G
K
F
T
F
D
V
E
K
S
E
Site 46
T385
V
E
K
S
E
I
Q
T
F
H
L
Q
N
D
P
Site 47
Y416
H
P
R
F
T
C
L
Y
R
V
R
A
H
G
V
Site 48
S426
R
A
H
G
V
R
T
S
E
G
A
E
G
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation