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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DMAP1
Full Name:
DNA methyltransferase 1-associated protein 1
Alias:
DNA methyltransferase 1 associated protein 1; DNA methyltransferase 1-associated protein 1; DNMAP1; DNMT1-associated protein 1; DNMTAP1; EAF2; FLJ11543; KIAA1425; MEAF2; SWC4
Type:
Transcription, coactivator/corepressor
Mass (Da):
52993
Number AA:
467
UniProt ID:
Q9NPF5
International Prot ID:
IPI00219919
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0001558
GO:0006139
GO:0006259
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
G
P
E
G
D
A
A
S
G
T
I
S
K
K
D
Site 2
T24
E
G
D
A
A
S
G
T
I
S
K
K
D
I
I
Site 3
S26
D
A
A
S
G
T
I
S
K
K
D
I
I
N
P
Site 4
S38
I
N
P
D
K
K
K
S
K
K
S
S
E
T
L
Site 5
S41
D
K
K
K
S
K
K
S
S
E
T
L
T
F
K
Site 6
S42
K
K
K
S
K
K
S
S
E
T
L
T
F
K
R
Site 7
T46
K
K
S
S
E
T
L
T
F
K
R
P
E
G
M
Site 8
Y58
E
G
M
H
R
E
V
Y
A
L
L
Y
S
D
K
Site 9
S74
D
A
P
P
L
L
P
S
D
T
G
Q
G
Y
R
Site 10
T76
P
P
L
L
P
S
D
T
G
Q
G
Y
R
T
V
Site 11
T82
D
T
G
Q
G
Y
R
T
V
K
A
K
L
G
S
Site 12
S89
T
V
K
A
K
L
G
S
K
K
V
R
P
W
K
Site 13
Y124
A
A
E
E
G
K
D
Y
P
F
A
R
F
N
K
Site 14
T132
P
F
A
R
F
N
K
T
V
Q
V
P
V
Y
S
Site 15
Y138
K
T
V
Q
V
P
V
Y
S
E
Q
E
Y
Q
L
Site 16
Y143
P
V
Y
S
E
Q
E
Y
Q
L
Y
L
H
D
D
Site 17
Y146
S
E
Q
E
Y
Q
L
Y
L
H
D
D
A
W
T
Site 18
S164
T
D
H
L
F
D
L
S
R
R
F
D
L
R
F
Site 19
Y178
F
V
V
I
H
D
R
Y
D
H
Q
Q
F
K
K
Site 20
S187
H
Q
Q
F
K
K
R
S
V
E
D
L
K
E
R
Site 21
Y196
E
D
L
K
E
R
Y
Y
H
I
C
A
K
L
A
Site 22
Y234
K
E
Q
L
E
R
L
Y
N
R
T
P
E
Q
V
Site 23
T237
L
E
R
L
Y
N
R
T
P
E
Q
V
A
E
E
Site 24
Y246
E
Q
V
A
E
E
E
Y
L
L
Q
E
L
R
K
Site 25
T273
Q
D
L
Q
K
L
I
T
A
A
D
T
T
A
E
Site 26
T284
T
T
A
E
Q
R
R
T
E
R
K
A
P
K
K
Site 27
S317
I
K
F
P
D
F
K
S
A
G
V
T
L
R
S
Site 28
T321
D
F
K
S
A
G
V
T
L
R
S
Q
R
M
K
Site 29
S324
S
A
G
V
T
L
R
S
Q
R
M
K
L
P
S
Site 30
S331
S
Q
R
M
K
L
P
S
S
V
G
Q
K
K
I
Site 31
S332
Q
R
M
K
L
P
S
S
V
G
Q
K
K
I
K
Site 32
S353
L
E
L
G
V
E
L
S
P
T
P
T
E
E
L
Site 33
T355
L
G
V
E
L
S
P
T
P
T
E
E
L
V
H
Site 34
T357
V
E
L
S
P
T
P
T
E
E
L
V
H
M
F
Site 35
S369
H
M
F
N
E
L
R
S
D
L
V
L
L
Y
E
Site 36
T409
G
V
L
G
G
P
A
T
P
A
S
G
P
G
P
Site 37
S412
G
G
P
A
T
P
A
S
G
P
G
P
A
S
A
Site 38
S418
A
S
G
P
G
P
A
S
A
E
P
A
V
T
E
Site 39
T424
A
S
A
E
P
A
V
T
E
P
G
L
G
P
D
Site 40
T435
L
G
P
D
P
K
D
T
I
I
D
V
V
G
A
Site 41
T445
D
V
V
G
A
P
L
T
P
N
S
R
K
R
R
Site 42
S448
G
A
P
L
T
P
N
S
R
K
R
R
E
S
A
Site 43
S454
N
S
R
K
R
R
E
S
A
S
S
S
S
S
V
Site 44
S456
R
K
R
R
E
S
A
S
S
S
S
S
V
K
K
Site 45
S457
K
R
R
E
S
A
S
S
S
S
S
V
K
K
A
Site 46
S458
R
R
E
S
A
S
S
S
S
S
V
K
K
A
K
Site 47
S460
E
S
A
S
S
S
S
S
V
K
K
A
K
K
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation