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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FZD3
Full Name:
Frizzled-3
Alias:
Type:
Mass (Da):
76263
Number AA:
666
UniProt ID:
Q9NPG1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T44
Q
D
L
P
Y
N
T
T
F
M
P
N
L
L
N
Site 2
S74
P
M
V
N
L
D
C
S
R
D
F
R
P
F
L
Site 3
T96
C
M
E
Y
G
R
V
T
L
P
C
R
R
L
C
Site 4
Y107
R
R
L
C
Q
R
A
Y
S
E
C
S
K
L
M
Site 5
S108
R
L
C
Q
R
A
Y
S
E
C
S
K
L
M
E
Site 6
Y137
F
P
D
C
D
E
P
Y
P
R
L
V
D
L
N
Site 7
Y161
P
V
A
V
Q
R
D
Y
G
F
W
C
P
R
E
Site 8
Y177
K
I
D
P
D
L
G
Y
S
F
L
H
V
R
D
Site 9
Y193
S
P
P
C
P
N
M
Y
F
R
R
E
E
L
S
Site 10
S200
Y
F
R
R
E
E
L
S
F
A
R
Y
F
I
G
Site 11
T229
L
T
F
L
I
D
V
T
R
F
R
Y
P
E
R
Site 12
Y233
I
D
V
T
R
F
R
Y
P
E
R
P
I
I
F
Site 13
T276
P
A
Q
Y
K
A
S
T
V
T
Q
G
S
H
N
Site 14
Y461
I
Q
E
R
C
R
E
Y
H
I
P
C
P
Y
Q
Site 15
T542
S
L
L
R
D
P
N
T
P
I
I
R
K
S
R
Site 16
S548
N
T
P
I
I
R
K
S
R
G
T
S
T
Q
G
Site 17
T551
I
I
R
K
S
R
G
T
S
T
Q
G
T
S
T
Site 18
S552
I
R
K
S
R
G
T
S
T
Q
G
T
S
T
H
Site 19
T553
R
K
S
R
G
T
S
T
Q
G
T
S
T
H
A
Site 20
T556
R
G
T
S
T
Q
G
T
S
T
H
A
S
S
T
Site 21
S557
G
T
S
T
Q
G
T
S
T
H
A
S
S
T
Q
Site 22
T558
T
S
T
Q
G
T
S
T
H
A
S
S
T
Q
L
Site 23
S561
Q
G
T
S
T
H
A
S
S
T
Q
L
A
M
V
Site 24
S573
A
M
V
D
D
Q
R
S
K
A
G
S
I
H
S
Site 25
S577
D
Q
R
S
K
A
G
S
I
H
S
K
V
S
S
Site 26
S580
S
K
A
G
S
I
H
S
K
V
S
S
Y
H
G
Site 27
S583
G
S
I
H
S
K
V
S
S
Y
H
G
S
L
H
Site 28
S584
S
I
H
S
K
V
S
S
Y
H
G
S
L
H
R
Site 29
S588
K
V
S
S
Y
H
G
S
L
H
R
S
R
D
G
Site 30
S592
Y
H
G
S
L
H
R
S
R
D
G
R
Y
T
P
Site 31
Y597
H
R
S
R
D
G
R
Y
T
P
C
S
Y
R
G
Site 32
T598
R
S
R
D
G
R
Y
T
P
C
S
Y
R
G
M
Site 33
S601
D
G
R
Y
T
P
C
S
Y
R
G
M
E
E
R
Site 34
S613
E
E
R
L
P
H
G
S
M
S
R
L
T
D
H
Site 35
S615
R
L
P
H
G
S
M
S
R
L
T
D
H
S
R
Site 36
T618
H
G
S
M
S
R
L
T
D
H
S
R
H
S
S
Site 37
S621
M
S
R
L
T
D
H
S
R
H
S
S
S
H
R
Site 38
S624
L
T
D
H
S
R
H
S
S
S
H
R
L
N
E
Site 39
S625
T
D
H
S
R
H
S
S
S
H
R
L
N
E
Q
Site 40
S626
D
H
S
R
H
S
S
S
H
R
L
N
E
Q
S
Site 41
S633
S
H
R
L
N
E
Q
S
R
H
S
S
I
R
D
Site 42
S636
L
N
E
Q
S
R
H
S
S
I
R
D
L
S
N
Site 43
S637
N
E
Q
S
R
H
S
S
I
R
D
L
S
N
N
Site 44
S642
H
S
S
I
R
D
L
S
N
N
P
M
T
H
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation