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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BRD7
Full Name:
Bromodomain-containing protein 7
Alias:
75 kDa bromodomain protein; BP75; Bromodomain containing 7; CELTIX1; NAG4; Protein CELTIX-1
Type:
Cell cycle regulation; Transcription regulation; Histone-binding protein
Mass (Da):
74139
Number AA:
651
UniProt ID:
Q9NPI1
International Prot ID:
IPI00001707
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0042393
GO:0008134
GO:0008134
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0006357
GO:0007154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
K
K
H
K
K
H
K
S
D
K
H
L
Y
E
E
Site 2
Y15
H
K
S
D
K
H
L
Y
E
E
Y
V
E
K
P
Site 3
Y18
D
K
H
L
Y
E
E
Y
V
E
K
P
L
K
L
Site 4
S38
G
N
E
V
T
E
L
S
T
G
S
S
G
H
D
Site 5
S42
T
E
L
S
T
G
S
S
G
H
D
S
S
L
F
Site 6
S46
T
G
S
S
G
H
D
S
S
L
F
E
D
K
N
Site 7
S47
G
S
S
G
H
D
S
S
L
F
E
D
K
N
D
Site 8
T122
L
P
P
E
K
P
L
T
S
S
L
A
K
Q
E
Site 9
T134
K
Q
E
E
V
E
Q
T
P
L
Q
E
A
L
N
Site 10
S153
Q
L
Q
R
K
D
P
S
A
F
F
S
F
P
V
Site 11
T180
K
H
P
M
D
F
S
T
M
K
E
K
I
K
N
Site 12
Y190
E
K
I
K
N
N
D
Y
Q
S
I
E
E
L
K
Site 13
S192
I
K
N
N
D
Y
Q
S
I
E
E
L
K
D
N
Site 14
Y210
M
C
T
N
A
M
I
Y
N
K
P
E
T
I
Y
Site 15
Y217
Y
N
K
P
E
T
I
Y
Y
K
A
A
K
K
L
Site 16
Y218
N
K
P
E
T
I
Y
Y
K
A
A
K
K
L
L
Site 17
S227
A
A
K
K
L
L
H
S
G
M
K
I
L
S
Q
Site 18
S233
H
S
G
M
K
I
L
S
Q
E
R
I
Q
S
L
Site 19
S239
L
S
Q
E
R
I
Q
S
L
K
Q
S
I
D
F
Site 20
S243
R
I
Q
S
L
K
Q
S
I
D
F
M
A
D
L
Site 21
T260
T
R
K
Q
K
D
G
T
D
T
S
Q
S
G
E
Site 22
S263
Q
K
D
G
T
D
T
S
Q
S
G
E
D
G
G
Site 23
S265
D
G
T
D
T
S
Q
S
G
E
D
G
G
C
W
Site 24
S279
W
Q
R
E
R
E
D
S
G
D
A
E
A
H
A
Site 25
S289
A
E
A
H
A
F
K
S
P
S
K
E
N
K
K
Site 26
S291
A
H
A
F
K
S
P
S
K
E
N
K
K
K
D
Site 27
S308
M
L
E
D
K
F
K
S
N
N
L
E
R
E
Q
Site 28
S325
L
D
R
I
V
K
E
S
G
G
K
L
T
R
R
Site 29
T330
K
E
S
G
G
K
L
T
R
R
L
V
N
S
Q
Site 30
S336
L
T
R
R
L
V
N
S
Q
C
E
F
E
R
R
Site 31
T348
E
R
R
K
P
D
G
T
T
T
L
G
L
L
H
Site 32
T349
R
R
K
P
D
G
T
T
T
L
G
L
L
H
P
Site 33
T375
P
V
R
L
G
M
T
T
G
R
L
Q
S
G
V
Site 34
S380
M
T
T
G
R
L
Q
S
G
V
N
T
L
Q
G
Site 35
T384
R
L
Q
S
G
V
N
T
L
Q
G
F
K
E
D
Site 36
T397
E
D
K
R
N
K
V
T
P
V
L
Y
L
N
Y
Site 37
Y401
N
K
V
T
P
V
L
Y
L
N
Y
G
P
Y
S
Site 38
Y404
T
P
V
L
Y
L
N
Y
G
P
Y
S
S
Y
A
Site 39
Y407
L
Y
L
N
Y
G
P
Y
S
S
Y
A
P
H
Y
Site 40
S409
L
N
Y
G
P
Y
S
S
Y
A
P
H
Y
D
S
Site 41
Y414
Y
S
S
Y
A
P
H
Y
D
S
T
F
A
N
I
Site 42
S416
S
Y
A
P
H
Y
D
S
T
F
A
N
I
S
K
Site 43
T417
Y
A
P
H
Y
D
S
T
F
A
N
I
S
K
D
Site 44
S422
D
S
T
F
A
N
I
S
K
D
D
S
D
L
I
Site 45
S426
A
N
I
S
K
D
D
S
D
L
I
Y
S
T
Y
Site 46
Y430
K
D
D
S
D
L
I
Y
S
T
Y
G
E
D
S
Site 47
Y433
S
D
L
I
Y
S
T
Y
G
E
D
S
D
L
P
Site 48
S437
Y
S
T
Y
G
E
D
S
D
L
P
S
D
F
S
Site 49
S441
G
E
D
S
D
L
P
S
D
F
S
I
H
E
F
Site 50
S444
S
D
L
P
S
D
F
S
I
H
E
F
L
A
T
Site 51
T468
D
S
L
L
D
V
L
T
K
G
G
H
S
R
T
Site 52
S482
T
L
Q
E
M
E
M
S
L
P
E
D
E
G
H
Site 53
T502
T
A
K
E
M
E
I
T
E
V
E
P
P
G
R
Site 54
S512
E
P
P
G
R
L
D
S
S
T
Q
D
R
L
I
Site 55
S513
P
P
G
R
L
D
S
S
T
Q
D
R
L
I
A
Site 56
T514
P
G
R
L
D
S
S
T
Q
D
R
L
I
A
L
Site 57
S536
V
P
V
E
V
F
D
S
E
E
A
E
I
F
Q
Site 58
T549
F
Q
K
K
L
D
E
T
T
R
L
L
R
E
L
Site 59
S565
E
A
Q
N
E
R
L
S
T
R
P
P
P
N
M
Site 60
T566
A
Q
N
E
R
L
S
T
R
P
P
P
N
M
I
Site 61
T601
K
E
L
A
Q
Q
V
T
P
G
D
I
V
S
T
Site 62
Y609
P
G
D
I
V
S
T
Y
G
V
R
K
A
M
G
Site 63
T632
E
N
N
F
V
D
L
T
E
D
T
E
E
P
K
Site 64
T635
F
V
D
L
T
E
D
T
E
E
P
K
K
T
D
Site 65
T641
D
T
E
E
P
K
K
T
D
V
A
E
C
G
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation