PhosphoNET

           
Protein Info 
   
Short Name:  MED4
Full Name:  Mediator of RNA polymerase II transcription subunit 4
Alias:  activator-recruited cofactor 36 kDa component; ARC36; DRIP36; FLJ10956; HSPC126; mediator complex 4; mediator complex subunit 4; mediator of RNA polymerase II transcription 4; RP11-90M2.2; TRAP/SMCC/PC2 subunit p36; TRAP36; VDRIP; vitamin D3 receptor-interacting protein complex 36 kDa
Type: 
Mass (Da):  29750
Number AA: 
UniProt ID:  Q9NPJ6
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0016592   Uniprot OncoNet
Molecular Function:  GO:0016455  GO:0030374  GO:0004872 PhosphoSite+ KinaseNET
Biological Process:  GO:0030521  GO:0006357  GO:0006367 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S25LGVAGGNSTRERLLS
Site 2S32STRERLLSALEDLEV
Site 3S105KEVEKRDSDIQQLQK
Site 4Y126QILATAVYQAKEKLK
Site 5S134QAKEKLKSIEKARKG
Site 6S144KARKGAISSEEIIKY
Site 7S145ARKGAISSEEIIKYA
Site 8Y151SSEEIIKYAHRISAS
Site 9T166NAVCAPLTWVPGDPR
Site 10Y176PGDPRRPYPTDLEMR
Site 11T178DPRRPYPTDLEMRSG
Site 12T195GQMNNPSTNGVNGHL
Site 13Y220PDVLAPQYPWQSNDM
Site 14S237NMLPPNHSSDFLLEP
Site 15S259EDDVEIMSTDSSSSS
Site 16T260DDVEIMSTDSSSSSS
Site 17S262VEIMSTDSSSSSSES
Site 18S263EIMSTDSSSSSSESD
Site 19S264IMSTDSSSSSSESD_
Site 20S265MSTDSSSSSSESD__
Site 21S266STDSSSSSSESD___
Site 22S267TDSSSSSSESD____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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