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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRTAC1
Full Name:
Cartilage acidic protein 1
Alias:
68 kDa chondrocyte-expressed protein; ASPIC; ASPIC1, CEP68
Type:
Mass (Da):
71421
Number AA:
661
UniProt ID:
Q9NQ79
International Prot ID:
IPI00451624
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
A
P
S
A
D
P
G
M
S
R
Site 2
S28
F
L
P
I
T
E
G
S
Q
R
A
E
P
M
F
Site 3
T39
E
P
M
F
T
A
V
T
N
S
V
L
P
P
D
Site 4
Y47
N
S
V
L
P
P
D
Y
D
S
N
P
T
Q
L
Site 5
S49
V
L
P
P
D
Y
D
S
N
P
T
Q
L
N
Y
Site 6
Y85
G
P
N
L
V
L
K
Y
D
R
A
Q
K
R
L
Site 7
S102
I
A
V
D
E
R
S
S
P
Y
Y
A
L
R
D
Site 8
Y105
D
E
R
S
S
P
Y
Y
A
L
R
D
R
Q
G
Site 9
Y131
G
D
G
R
E
E
I
Y
F
L
N
T
N
N
A
Site 10
T144
N
A
F
S
G
V
A
T
Y
T
D
K
L
F
K
Site 11
S162
N
R
W
E
D
I
L
S
D
E
V
N
V
A
R
Site 12
S188
A
C
V
D
R
K
G
S
G
R
Y
S
I
Y
I
Site 13
S192
R
K
G
S
G
R
Y
S
I
Y
I
A
N
Y
A
Site 14
Y194
G
S
G
R
Y
S
I
Y
I
A
N
Y
A
Y
G
Site 15
S216
I
E
M
D
P
E
A
S
D
L
S
R
G
I
L
Site 16
S235
V
A
A
E
A
G
V
S
K
Y
T
G
G
R
G
Site 17
Y237
A
E
A
G
V
S
K
Y
T
G
G
R
G
V
S
Site 18
S254
P
I
L
S
S
S
A
S
D
I
F
C
D
N
E
Site 19
T275
F
H
N
R
G
D
G
T
F
V
D
A
A
A
S
Site 20
Y310
D
G
K
V
D
I
V
Y
G
N
W
N
G
P
H
Site 21
Y320
W
N
G
P
H
R
L
Y
L
Q
M
S
T
H
G
Site 22
S336
V
R
F
R
D
I
A
S
P
K
F
S
M
P
S
Site 23
S340
D
I
A
S
P
K
F
S
M
P
S
P
V
R
T
Site 24
S343
S
P
K
F
S
M
P
S
P
V
R
T
V
I
T
Site 25
T347
S
M
P
S
P
V
R
T
V
I
T
A
D
F
D
Site 26
Y368
I
F
F
N
N
I
A
Y
R
S
S
S
A
N
R
Site 27
S371
N
N
I
A
Y
R
S
S
S
A
N
R
L
F
R
Site 28
S372
N
I
A
Y
R
S
S
S
A
N
R
L
F
R
V
Site 29
T405
L
E
P
E
G
R
G
T
G
G
V
V
T
D
F
Site 30
T410
R
G
T
G
G
V
V
T
D
F
D
G
D
G
M
Site 31
S433
E
S
M
A
Q
P
L
S
V
F
R
G
N
Q
G
Site 32
T452
W
L
R
V
V
P
R
T
R
F
G
A
F
A
R
Site 33
Y466
R
G
A
K
V
V
L
Y
T
K
K
S
G
A
H
Site 34
T467
G
A
K
V
V
L
Y
T
K
K
S
G
A
H
L
Site 35
S502
L
G
K
D
E
A
S
S
V
E
V
T
W
P
D
Site 36
T506
E
A
S
S
V
E
V
T
W
P
D
G
K
M
V
Site 37
S514
W
P
D
G
K
M
V
S
R
N
V
A
S
G
E
Site 38
Y530
N
S
V
L
E
I
L
Y
P
R
D
E
D
T
L
Site 39
T536
L
Y
P
R
D
E
D
T
L
Q
D
P
A
P
L
Site 40
T588
Y
G
S
Y
R
C
R
T
N
K
K
C
S
R
G
Site 41
Y596
N
K
K
C
S
R
G
Y
E
P
N
E
D
G
T
Site 42
T603
Y
E
P
N
E
D
G
T
A
C
V
G
T
L
G
Site 43
T608
D
G
T
A
C
V
G
T
L
G
Q
S
P
G
P
Site 44
S612
C
V
G
T
L
G
Q
S
P
G
P
R
P
T
T
Site 45
T618
Q
S
P
G
P
R
P
T
T
P
T
A
A
A
A
Site 46
T619
S
P
G
P
R
P
T
T
P
T
A
A
A
A
T
Site 47
T621
G
P
R
P
T
T
P
T
A
A
A
A
T
A
A
Site 48
S651
D
G
D
L
N
L
G
S
V
V
K
E
S
C
E
Site 49
S656
L
G
S
V
V
K
E
S
C
E
P
S
C
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation