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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPRC5C
Full Name:
G-protein coupled receptor family C group 5 member C
Alias:
G protein-coupled receptor, family C, group 5, member C; GC5C; GPC5C; RAIG-3; RAIG3, G protein-coupled receptor family C group 5 member C precursor; Retinoic acid induced gene 3 protein; Retinoic acid-induced gene 3 protein
Type:
Receptor, GPCR
Mass (Da):
48193
Number AA:
441
UniProt ID:
Q9NQ84
International Prot ID:
IPI00099883
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031410
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004930
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
G
H
V
P
P
G
C
S
Q
G
L
N
P
L
Y
Site 2
Y39
S
Q
G
L
N
P
L
Y
Y
N
L
C
D
R
S
Site 3
Y40
Q
G
L
N
P
L
Y
Y
N
L
C
D
R
S
G
Site 4
T81
S
L
P
F
V
Q
D
T
K
K
R
S
L
L
G
Site 5
S85
V
Q
D
T
K
K
R
S
L
L
G
T
Q
V
F
Site 6
S114
C
V
V
K
P
D
F
S
T
C
A
S
R
R
F
Site 7
T115
V
V
K
P
D
F
S
T
C
A
S
R
R
F
L
Site 8
S183
I
I
T
L
V
R
G
S
G
E
G
G
P
Q
G
Site 9
S192
E
G
G
P
Q
G
N
S
S
A
G
W
A
V
A
Site 10
S193
G
G
P
Q
G
N
S
S
A
G
W
A
V
A
S
Site 11
S272
Y
G
N
K
Q
H
N
S
P
T
W
D
D
P
T
Site 12
S301
F
Y
V
I
P
E
V
S
Q
V
T
K
S
S
P
Site 13
S306
E
V
S
Q
V
T
K
S
S
P
E
Q
S
Y
Q
Site 14
S307
V
S
Q
V
T
K
S
S
P
E
Q
S
Y
Q
G
Site 15
S311
T
K
S
S
P
E
Q
S
Y
Q
G
D
M
Y
P
Site 16
Y312
K
S
S
P
E
Q
S
Y
Q
G
D
M
Y
P
T
Site 17
Y317
Q
S
Y
Q
G
D
M
Y
P
T
R
G
V
G
Y
Site 18
Y324
Y
P
T
R
G
V
G
Y
E
T
I
L
K
E
Q
Site 19
T326
T
R
G
V
G
Y
E
T
I
L
K
E
Q
K
G
Site 20
S335
L
K
E
Q
K
G
Q
S
M
F
V
E
N
K
A
Site 21
S356
V
A
A
K
R
P
V
S
P
Y
S
G
Y
N
G
Site 22
Y358
A
K
R
P
V
S
P
Y
S
G
Y
N
G
Q
L
Site 23
S359
K
R
P
V
S
P
Y
S
G
Y
N
G
Q
L
L
Site 24
Y361
P
V
S
P
Y
S
G
Y
N
G
Q
L
L
T
S
Site 25
S368
Y
N
G
Q
L
L
T
S
V
Y
Q
P
T
E
M
Site 26
Y370
G
Q
L
L
T
S
V
Y
Q
P
T
E
M
A
L
Site 27
S383
A
L
M
H
K
V
P
S
E
G
A
Y
D
I
I
Site 28
Y387
K
V
P
S
E
G
A
Y
D
I
I
L
P
R
A
Site 29
S398
L
P
R
A
T
A
N
S
Q
V
M
G
S
A
N
Site 30
S403
A
N
S
Q
V
M
G
S
A
N
S
T
L
R
A
Site 31
S406
Q
V
M
G
S
A
N
S
T
L
R
A
E
D
M
Site 32
T407
V
M
G
S
A
N
S
T
L
R
A
E
D
M
Y
Site 33
Y414
T
L
R
A
E
D
M
Y
S
A
Q
S
H
Q
A
Site 34
S415
L
R
A
E
D
M
Y
S
A
Q
S
H
Q
A
A
Site 35
S418
E
D
M
Y
S
A
Q
S
H
Q
A
A
T
P
P
Site 36
T423
A
Q
S
H
Q
A
A
T
P
P
K
D
G
K
N
Site 37
S431
P
P
K
D
G
K
N
S
Q
V
F
R
N
P
Y
Site 38
Y438
S
Q
V
F
R
N
P
Y
V
W
D
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation