KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TrpV5
Full Name:
Transient receptor potential cation channel subfamily V member 5
Alias:
Calcium transport protein 2; CaT2; ECaC; ECaC1; Epithelial calcium channel 1; Osm-9-like TRP channel 3; OTRPC3; Transient receptor potential cation channel, subfamily V, member 5
Type:
Channel protein, cation
Mass (Da):
82551
Number AA:
729
UniProt ID:
Q9NQA5
International Prot ID:
IPI00302133
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005262
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0051262
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
P
K
A
E
G
P
G
S
Q
L
Q
K
L
L
P
Site 2
S21
Q
L
Q
K
L
L
P
S
F
L
V
R
E
Q
D
Site 3
S47
Q
Q
K
R
I
L
E
S
P
L
L
R
A
S
K
Site 4
S53
E
S
P
L
L
R
A
S
K
E
N
D
L
S
V
Site 5
S59
A
S
K
E
N
D
L
S
V
L
R
Q
L
L
L
Site 6
T69
R
Q
L
L
L
D
C
T
C
D
V
R
Q
R
G
Site 7
S142
A
L
L
T
R
R
A
S
V
S
A
R
A
T
G
Site 8
S144
L
T
R
R
A
S
V
S
A
R
A
T
G
T
A
Site 9
T148
A
S
V
S
A
R
A
T
G
T
A
F
R
R
S
Site 10
T150
V
S
A
R
A
T
G
T
A
F
R
R
S
P
R
Site 11
S155
T
G
T
A
F
R
R
S
P
R
N
L
I
Y
F
Site 12
Y161
R
S
P
R
N
L
I
Y
F
G
E
H
P
L
S
Site 13
S194
A
D
I
R
A
Q
D
S
L
G
N
T
V
L
H
Site 14
Y222
M
Y
N
L
L
L
S
Y
D
G
H
G
D
H
L
Site 15
T269
K
R
R
H
I
Q
W
T
Y
G
P
L
T
S
I
Site 16
Y270
R
R
H
I
Q
W
T
Y
G
P
L
T
S
I
L
Site 17
T281
T
S
I
L
Y
D
L
T
E
I
D
S
W
G
E
Site 18
S285
Y
D
L
T
E
I
D
S
W
G
E
E
L
S
F
Site 19
S298
S
F
L
E
L
V
V
S
S
D
K
R
E
A
R
Site 20
S299
F
L
E
L
V
V
S
S
D
K
R
E
A
R
Q
Site 21
T311
A
R
Q
I
L
E
Q
T
P
V
K
E
L
V
S
Site 22
S318
T
P
V
K
E
L
V
S
F
K
W
N
K
Y
G
Site 23
T360
K
F
R
G
G
N
R
T
H
S
R
D
I
T
I
Site 24
S362
R
G
G
N
R
T
H
S
R
D
I
T
I
L
Q
Site 25
T366
R
T
H
S
R
D
I
T
I
L
Q
Q
K
L
L
Site 26
Y377
Q
K
L
L
Q
E
A
Y
E
T
R
E
D
I
I
Site 27
T379
L
L
Q
E
A
Y
E
T
R
E
D
I
I
R
L
Site 28
T419
A
S
R
Y
F
G
K
T
I
L
G
G
P
F
H
Site 29
S519
F
Q
T
E
D
P
T
S
L
G
Q
F
Y
D
Y
Site 30
Y647
N
P
L
R
V
L
R
Y
V
E
V
F
K
N
S
Site 31
S654
Y
V
E
V
F
K
N
S
D
K
E
D
D
Q
E
Site 32
S669
H
P
S
E
K
Q
P
S
G
A
E
S
G
T
L
Site 33
S673
K
Q
P
S
G
A
E
S
G
T
L
A
R
A
S
Site 34
T675
P
S
G
A
E
S
G
T
L
A
R
A
S
L
A
Site 35
S680
S
G
T
L
A
R
A
S
L
A
L
P
T
S
S
Site 36
T685
R
A
S
L
A
L
P
T
S
S
L
S
R
T
A
Site 37
S687
S
L
A
L
P
T
S
S
L
S
R
T
A
S
Q
Site 38
S689
A
L
P
T
S
S
L
S
R
T
A
S
Q
S
S
Site 39
T691
P
T
S
S
L
S
R
T
A
S
Q
S
S
S
H
Site 40
S693
S
S
L
S
R
T
A
S
Q
S
S
S
H
R
G
Site 41
S695
L
S
R
T
A
S
Q
S
S
S
H
R
G
W
E
Site 42
S696
S
R
T
A
S
Q
S
S
S
H
R
G
W
E
I
Site 43
S697
R
T
A
S
Q
S
S
S
H
R
G
W
E
I
L
Site 44
T708
W
E
I
L
R
Q
N
T
L
G
H
L
N
L
G
Site 45
S719
L
N
L
G
L
N
L
S
E
G
D
G
E
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation