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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SMCR7L
Full Name:
Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like
Alias:
SMC7L; YV002
Type:
Mass (Da):
51293
Number AA:
463
UniProt ID:
Q9NQG6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005739
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y50
T
L
A
V
K
R
M
Y
D
R
A
I
S
A
P
Site 2
S55
R
M
Y
D
R
A
I
S
A
P
T
S
P
T
R
Site 3
T58
D
R
A
I
S
A
P
T
S
P
T
R
L
S
H
Site 4
S59
R
A
I
S
A
P
T
S
P
T
R
L
S
H
S
Site 5
T61
I
S
A
P
T
S
P
T
R
L
S
H
S
G
K
Site 6
S64
P
T
S
P
T
R
L
S
H
S
G
K
R
S
W
Site 7
S66
S
P
T
R
L
S
H
S
G
K
R
S
W
E
E
Site 8
S70
L
S
H
S
G
K
R
S
W
E
E
P
N
W
M
Site 9
S79
E
E
P
N
W
M
G
S
P
R
L
L
N
R
D
Site 10
T89
L
L
N
R
D
M
K
T
G
L
S
R
S
L
Q
Site 11
S92
R
D
M
K
T
G
L
S
R
S
L
Q
T
L
P
Site 12
S94
M
K
T
G
L
S
R
S
L
Q
T
L
P
T
D
Site 13
T100
R
S
L
Q
T
L
P
T
D
S
S
T
F
D
T
Site 14
S102
L
Q
T
L
P
T
D
S
S
T
F
D
T
D
T
Site 15
S103
Q
T
L
P
T
D
S
S
T
F
D
T
D
T
F
Site 16
T104
T
L
P
T
D
S
S
T
F
D
T
D
T
F
C
Site 17
T107
T
D
S
S
T
F
D
T
D
T
F
C
P
P
R
Site 18
T109
S
S
T
F
D
T
D
T
F
C
P
P
R
P
K
Site 19
S129
G
Q
V
D
L
K
K
S
R
L
R
M
S
L
Q
Site 20
S134
K
K
S
R
L
R
M
S
L
Q
E
K
L
L
T
Site 21
T141
S
L
Q
E
K
L
L
T
Y
Y
R
N
R
A
A
Site 22
Y142
L
Q
E
K
L
L
T
Y
Y
R
N
R
A
A
I
Site 23
Y185
D
M
P
L
R
D
M
Y
L
S
G
S
L
Y
D
Site 24
S187
P
L
R
D
M
Y
L
S
G
S
L
Y
D
D
L
Site 25
S189
R
D
M
Y
L
S
G
S
L
Y
D
D
L
Q
V
Site 26
Y240
V
R
R
E
N
P
E
Y
F
P
R
G
S
S
Y
Site 27
T261
G
G
Y
L
S
P
K
T
V
A
D
T
F
E
K
Site 28
T265
S
P
K
T
V
A
D
T
F
E
K
V
V
A
G
Site 29
T297
A
P
P
P
E
A
L
T
L
E
V
Q
Y
E
R
Site 30
Y302
A
L
T
L
E
V
Q
Y
E
R
D
K
H
L
F
Site 31
S340
Y
D
N
L
W
R
L
S
L
R
P
A
E
T
A
Site 32
T346
L
S
L
R
P
A
E
T
A
R
L
R
A
L
D
Site 33
S357
R
A
L
D
Q
A
D
S
G
C
R
S
L
C
L
Site 34
S361
Q
A
D
S
G
C
R
S
L
C
L
K
I
L
K
Site 35
S400
A
Q
E
E
A
D
W
S
P
D
M
L
A
D
R
Site 36
T449
E
I
D
E
L
G
Y
T
L
Y
C
S
L
S
E
Site 37
Y451
D
E
L
G
Y
T
L
Y
C
S
L
S
E
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation