PhosphoNET

           
Protein Info 
   
Short Name:  DDX4
Full Name:  Probable ATP-dependent RNA helicase DDX4
Alias:  ATP-dependent RNA helicase DDX4; DEAD box 4; EC 3.6.1.-; Vasa
Type:  Ribonucleoprotein complex, Cytoplasm, Nucleus protein
Mass (Da):  79308
Number AA:  724
UniProt ID:  Q9NQI0
International Prot ID:  IPI00071483
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0008026  GO:0003676 PhosphoSite+ KinaseNET
Biological Process:  GO:0007275     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S16EINPHMSSYVPIFEK
Site 2Y17INPHMSSYVPIFEKD
Site 3Y26PIFEKDRYSGENGDN
Site 4S27IFEKDRYSGENGDNF
Site 5T37NGDNFNRTPASSSEM
Site 6S40NFNRTPASSSEMDDG
Site 7S41FNRTPASSSEMDDGP
Site 8S42NRTPASSSEMDDGPS
Site 9S49SEMDDGPSRRDHFMK
Site 10S57RRDHFMKSGFASGRN
Site 11S61FMKSGFASGRNFGNR
Site 12T79ECNKRDNTSTMGGFG
Site 13T81NKRDNTSTMGGFGVG
Site 14S90GGFGVGKSFGNRGFS
Site 15S97SFGNRGFSNSRFEDG
Site 16S99GNRGFSNSRFEDGDS
Site 17S106SRFEDGDSSGFWRES
Site 18S107RFEDGDSSGFWRESS
Site 19S113SSGFWRESSNDCEDN
Site 20S114SGFWRESSNDCEDNP
Site 21T122NDCEDNPTRNRGFSK
Site 22S128PTRNRGFSKRGGYRD
Site 23Y133GFSKRGGYRDGNNSE
Site 24S139GYRDGNNSEASGPYR
Site 25S142DGNNSEASGPYRRGG
Site 26S152YRRGGRGSFRGCRGG
Site 27S164RGGFGLGSPNNDLDP
Site 28S184RTGGLFGSRRPVLSG
Site 29S190GSRRPVLSGTGNGDT
Site 30T197SGTGNGDTSQSRSGS
Site 31S198GTGNGDTSQSRSGSG
Site 32S200GNGDTSQSRSGSGSE
Site 33S202GDTSQSRSGSGSERG
Site 34S204TSQSRSGSGSERGGY
Site 35S206QSRSGSGSERGGYKG
Site 36Y211SGSERGGYKGLNEEV
Site 37T220GLNEEVITGSGKNSW
Site 38S222NEEVITGSGKNSWKS
Site 39S226ITGSGKNSWKSEAEG
Site 40S229SGKNSWKSEAEGGES
Site 41S236SEAEGGESSDTQGPK
Site 42S237EAEGGESSDTQGPKV
Site 43T239EGGESSDTQGPKVTY
Site 44T245DTQGPKVTYIPPPPP
Site 45Y246TQGPKVTYIPPPPPE
Site 46S257PPPEDEDSIFAHYQT
Site 47Y262EDSIFAHYQTGINFD
Site 48T312KAGYTKLTPVQKYSI
Site 49T339AQTGSGKTAAFLLPI
Site 50T356HMMHDGITASRFKEL
Site 51S358MHDGITASRFKELQE
Site 52Y382RELVNQIYLEARKFS
Site 53S389YLEARKFSFGTCVRA
Site 54Y400CVRAVVIYGGTQLGH
Site 55S408GGTQLGHSIRQIVQG
Site 56T422GCNILCATPGRLMDI
Site 57Y442IGLKQIKYLVLDEAD
Site 58S465PEMKKLISCPGMPSK
Site 59T477PSKEQRQTLMFSATF
Site 60T483QTLMFSATFPEEIQR
Site 61T518ACRDVQQTVLQVGQF
Site 62S526VLQVGQFSKREKLVE
Site 63T543RNIGDERTMVFVETK
Site 64T549RTMVFVETKKKADFI
Site 65T567LCQEKISTTSIHGDR
Site 66T620INFDLPSTIDEYVHR
Site 67Y624LPSTIDEYVHRIGRT
Site 68T637RTGRCGNTGRAISFF
Site 69S642GNTGRAISFFDLESD
Site 70S648ISFFDLESDNHLAQP
Site 71Y679EEIAFSTYIPGFSGS
Site 72S684STYIPGFSGSTRGNV
Site 73S686YIPGFSGSTRGNVFA
Site 74S694TRGNVFASVDTRKGK
Site 75S702VDTRKGKSTLNTAGF
Site 76T703DTRKGKSTLNTAGFS
Site 77T706KGKSTLNTAGFSSSQ
Site 78S712NTAGFSSSQAPNPVD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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