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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NIT2
Full Name:
Omega-amidase NIT2
Alias:
CUA002; NIT protein 2; nitrilase family, member 2
Type:
Mitochondrial; Hydrolase; EC 3.5.-.-
Mass (Da):
30608
Number AA:
276
UniProt ID:
Q9NQR4
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0016810
PhosphoSite+
KinaseNET
Biological Process:
GO:0006807
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
L
Q
I
S
S
I
K
S
D
N
V
T
R
A
C
Site 2
T22
S
I
K
S
D
N
V
T
R
A
C
S
F
I
R
Site 3
S26
D
N
V
T
R
A
C
S
F
I
R
E
A
A
T
Site 4
S40
T
Q
G
A
K
I
V
S
L
P
E
C
F
N
S
Site 5
S47
S
L
P
E
C
F
N
S
P
Y
G
A
K
Y
F
Site 6
Y49
P
E
C
F
N
S
P
Y
G
A
K
Y
F
P
E
Site 7
Y53
N
S
P
Y
G
A
K
Y
F
P
E
Y
A
E
K
Site 8
Y57
G
A
K
Y
F
P
E
Y
A
E
K
I
P
G
E
Site 9
S70
G
E
S
T
Q
K
L
S
E
V
A
K
E
C
S
Site 10
Y94
E
E
D
A
G
K
L
Y
N
T
C
A
V
F
G
Site 11
T96
D
A
G
K
L
Y
N
T
C
A
V
F
G
P
D
Site 12
T105
A
V
F
G
P
D
G
T
L
L
A
K
Y
R
K
Site 13
Y110
D
G
T
L
L
A
K
Y
R
K
I
H
L
F
D
Site 14
T125
I
D
V
P
G
K
I
T
F
Q
E
S
K
T
L
Site 15
S129
G
K
I
T
F
Q
E
S
K
T
L
S
P
G
D
Site 16
T131
I
T
F
Q
E
S
K
T
L
S
P
G
D
S
F
Site 17
S133
F
Q
E
S
K
T
L
S
P
G
D
S
F
S
T
Site 18
S137
K
T
L
S
P
G
D
S
F
S
T
F
D
T
P
Site 19
S139
L
S
P
G
D
S
F
S
T
F
D
T
P
Y
C
Site 20
T140
S
P
G
D
S
F
S
T
F
D
T
P
Y
C
R
Site 21
T143
D
S
F
S
T
F
D
T
P
Y
C
R
V
G
L
Site 22
Y145
F
S
T
F
D
T
P
Y
C
R
V
G
L
G
I
Site 23
Y202
R
A
V
D
N
Q
V
Y
V
A
T
A
S
P
A
Site 24
S207
Q
V
Y
V
A
T
A
S
P
A
R
D
D
K
A
Site 25
S215
P
A
R
D
D
K
A
S
Y
V
A
W
G
H
S
Site 26
Y216
A
R
D
D
K
A
S
Y
V
A
W
G
H
S
T
Site 27
Y243
G
T
E
E
A
I
V
Y
S
D
I
D
L
K
K
Site 28
S266
P
V
F
R
Q
K
R
S
D
L
Y
A
V
E
M
Site 29
Y269
R
Q
K
R
S
D
L
Y
A
V
E
M
K
K
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation