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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNGB3
Full Name:
Cyclic nucleotide-gated cation channel beta-3
Alias:
CNG channel beta 3; Cone photoreceptor cGMP- gated channel subunit beta; Cyclic nucleotide-gated cation channel beta 3; Cyclic nucleotide-gated cation channel modulatory subunit; Cyclic nucleotide-gated channel beta 3
Type:
Membrane, Photoreceptor outer segment, Integral membrane protein
Mass (Da):
92250
Number AA:
809
UniProt ID:
Q9NQW8
International Prot ID:
IPI00178093
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0030553
PhosphoSite+
KinaseNET
Biological Process:
GO:0006811
GO:0050896
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
E
N
N
E
N
E
Q
S
S
R
R
N
E
E
G
Site 2
S31
S
R
R
N
E
E
G
S
H
P
S
N
Q
S
Q
Site 3
T41
S
N
Q
S
Q
Q
T
T
A
Q
E
E
N
K
G
Site 4
S52
E
N
K
G
E
E
K
S
L
K
T
K
S
T
P
Site 5
S57
E
K
S
L
K
T
K
S
T
P
V
T
S
E
E
Site 6
T58
K
S
L
K
T
K
S
T
P
V
T
S
E
E
P
Site 7
T61
K
T
K
S
T
P
V
T
S
E
E
P
H
T
N
Site 8
S62
T
K
S
T
P
V
T
S
E
E
P
H
T
N
I
Site 9
T67
V
T
S
E
E
P
H
T
N
I
Q
D
K
L
S
Site 10
S74
T
N
I
Q
D
K
L
S
K
K
N
S
S
G
D
Site 11
S78
D
K
L
S
K
K
N
S
S
G
D
L
T
T
N
Site 12
T83
K
N
S
S
G
D
L
T
T
N
P
D
P
Q
N
Site 13
T97
N
A
A
E
P
T
G
T
V
P
E
Q
K
E
M
Site 14
S113
P
G
K
E
G
P
N
S
P
Q
N
K
P
P
A
Site 15
Y127
A
A
P
V
I
N
E
Y
A
D
A
Q
L
H
N
Site 16
T143
V
K
R
M
R
Q
R
T
A
L
Y
K
K
K
L
Site 17
S156
K
L
V
E
G
D
L
S
S
P
E
A
S
P
Q
Site 18
S157
L
V
E
G
D
L
S
S
P
E
A
S
P
Q
T
Site 19
S161
D
L
S
S
P
E
A
S
P
Q
T
A
K
P
T
Site 20
T164
S
P
E
A
S
P
Q
T
A
K
P
T
A
V
P
Site 21
S176
A
V
P
P
V
K
E
S
D
D
K
P
T
E
H
Site 22
Y184
D
D
K
P
T
E
H
Y
Y
R
L
L
W
F
K
Site 23
T198
K
V
K
K
M
P
L
T
E
Y
L
K
R
I
K
Site 24
Y200
K
K
M
P
L
T
E
Y
L
K
R
I
K
L
P
Site 25
S209
K
R
I
K
L
P
N
S
I
D
S
Y
T
D
R
Site 26
S212
K
L
P
N
S
I
D
S
Y
T
D
R
L
Y
L
Site 27
Y213
L
P
N
S
I
D
S
Y
T
D
R
L
Y
L
L
Site 28
T214
P
N
S
I
D
S
Y
T
D
R
L
Y
L
L
W
Site 29
Y244
P
L
R
L
V
F
P
Y
Q
T
A
D
N
I
H
Site 30
S287
G
G
D
I
I
V
D
S
N
E
L
R
K
H
Y
Site 31
Y294
S
N
E
L
R
K
H
Y
R
T
S
T
K
F
Q
Site 32
T296
E
L
R
K
H
Y
R
T
S
T
K
F
Q
L
D
Site 33
S297
L
R
K
H
Y
R
T
S
T
K
F
Q
L
D
V
Site 34
T298
R
K
H
Y
R
T
S
T
K
F
Q
L
D
V
A
Site 35
Y331
R
A
N
R
M
L
K
Y
T
S
F
F
E
F
N
Site 36
Y349
E
S
I
M
D
K
A
Y
I
Y
R
V
I
R
T
Site 37
Y377
V
Y
Y
W
A
S
N
Y
E
G
I
G
T
T
R
Site 38
T382
S
N
Y
E
G
I
G
T
T
R
W
V
Y
D
G
Site 39
Y387
I
G
T
T
R
W
V
Y
D
G
E
G
N
E
Y
Site 40
Y394
Y
D
G
E
G
N
E
Y
L
R
C
Y
Y
W
A
Site 41
Y398
G
N
E
Y
L
R
C
Y
Y
W
A
V
R
T
L
Site 42
Y399
N
E
Y
L
R
C
Y
Y
W
A
V
R
T
L
I
Site 43
Y454
A
A
T
A
N
Q
N
Y
F
R
A
C
M
D
D
Site 44
Y469
T
I
A
Y
M
N
N
Y
S
I
P
K
L
V
Q
Site 45
Y483
Q
K
R
V
R
T
W
Y
E
Y
T
W
D
S
Q
Site 46
S496
S
Q
R
M
L
D
E
S
D
L
L
K
T
L
P
Site 47
T501
D
E
S
D
L
L
K
T
L
P
T
T
V
Q
L
Site 48
Y545
L
R
L
K
S
V
L
Y
L
P
G
D
F
V
C
Site 49
Y562
G
E
I
G
K
E
M
Y
I
I
K
H
G
E
V
Site 50
T605
A
G
G
G
N
R
R
T
A
N
V
V
A
H
G
Site 51
T618
H
G
F
A
N
L
L
T
L
D
K
K
T
L
Q
Site 52
Y631
L
Q
E
I
L
V
H
Y
P
D
S
E
R
I
L
Site 53
S634
I
L
V
H
Y
P
D
S
E
R
I
L
M
K
K
Site 54
T652
L
L
K
Q
K
A
K
T
A
E
A
T
P
P
R
Site 55
T656
K
A
K
T
A
E
A
T
P
P
R
K
D
L
A
Site 56
T672
L
F
P
P
K
E
E
T
P
K
L
F
K
T
L
Site 57
T678
E
T
P
K
L
F
K
T
L
L
G
G
T
G
K
Site 58
S759
D
R
P
E
C
T
A
S
P
I
A
V
E
E
E
Site 59
S769
A
V
E
E
E
P
H
S
V
R
R
T
V
L
P
Site 60
T773
E
P
H
S
V
R
R
T
V
L
P
R
G
T
S
Site 61
T779
R
T
V
L
P
R
G
T
S
R
Q
S
L
I
I
Site 62
S780
T
V
L
P
R
G
T
S
R
Q
S
L
I
I
S
Site 63
S783
P
R
G
T
S
R
Q
S
L
I
I
S
M
A
P
Site 64
S787
S
R
Q
S
L
I
I
S
M
A
P
S
A
E
G
Site 65
T800
E
G
G
E
E
V
L
T
I
E
V
K
E
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation