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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRDM5
Full Name:
PR domain zinc finger protein 5
Alias:
PFM2; PR domain containing 5; PR domain-containing 5
Type:
Transcription factor
Mass (Da):
73062
Number AA:
630
UniProt ID:
Q9NQX1
International Prot ID:
IPI00032997
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0010843
GO:0016566
GO:0070491
PhosphoSite+
KinaseNET
Biological Process:
GO:0051567
GO:0016575
GO:0000278
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
M
Y
V
P
D
R
F
S
L
K
S
S
R
V
Q
Site 2
S14
P
D
R
F
S
L
K
S
S
R
V
Q
D
G
M
Site 3
S15
D
R
F
S
L
K
S
S
R
V
Q
D
G
M
G
Site 4
Y24
V
Q
D
G
M
G
L
Y
T
A
R
R
V
R
K
Site 5
T25
Q
D
G
M
G
L
Y
T
A
R
R
V
R
K
G
Site 6
Y54
D
L
D
E
N
M
D
Y
R
L
M
W
E
V
R
Site 7
Y69
G
S
K
G
E
V
L
Y
I
L
D
A
T
N
P
Site 8
S90
R
F
V
H
E
A
P
S
Q
E
Q
K
N
L
A
Site 9
Y107
Q
E
G
E
N
I
F
Y
L
A
V
E
D
I
E
Site 10
S126
L
L
I
G
Y
L
D
S
D
M
E
A
E
E
E
Site 11
T139
E
E
E
Q
Q
I
M
T
V
I
K
E
G
E
V
Site 12
S149
K
E
G
E
V
E
N
S
R
R
Q
S
T
A
G
Site 13
S153
V
E
N
S
R
R
Q
S
T
A
G
R
K
D
R
Site 14
T154
E
N
S
R
R
Q
S
T
A
G
R
K
D
R
L
Site 15
Y167
R
L
G
C
K
E
D
Y
A
C
P
Q
C
E
S
Site 16
S175
A
C
P
Q
C
E
S
S
F
T
S
E
D
I
L
Site 17
T177
P
Q
C
E
S
S
F
T
S
E
D
I
L
A
E
Site 18
S178
Q
C
E
S
S
F
T
S
E
D
I
L
A
E
H
Site 19
T188
I
L
A
E
H
L
Q
T
L
H
Q
K
P
T
E
Site 20
T222
Q
R
H
V
L
Q
C
T
A
K
S
S
L
K
E
Site 21
S225
V
L
Q
C
T
A
K
S
S
L
K
E
S
S
R
Site 22
S226
L
Q
C
T
A
K
S
S
L
K
E
S
S
R
S
Site 23
S230
A
K
S
S
L
K
E
S
S
R
S
F
Q
C
S
Site 24
S231
K
S
S
L
K
E
S
S
R
S
F
Q
C
S
V
Site 25
S233
S
L
K
E
S
S
R
S
F
Q
C
S
V
C
N
Site 26
S237
S
S
R
S
F
Q
C
S
V
C
N
S
S
F
S
Site 27
S241
F
Q
C
S
V
C
N
S
S
F
S
S
A
S
S
Site 28
S242
Q
C
S
V
C
N
S
S
F
S
S
A
S
S
F
Site 29
S244
S
V
C
N
S
S
F
S
S
A
S
S
F
E
Q
Site 30
S245
V
C
N
S
S
F
S
S
A
S
S
F
E
Q
H
Site 31
S248
S
S
F
S
S
A
S
S
F
E
Q
H
Q
E
T
Site 32
S268
R
F
V
C
K
A
D
S
C
G
K
R
L
K
S
Site 33
S275
S
C
G
K
R
L
K
S
K
D
A
L
K
R
H
Site 34
T288
R
H
Q
E
N
V
H
T
G
D
P
K
K
K
L
Site 35
S305
S
V
C
N
K
K
C
S
S
A
S
S
L
Q
E
Site 36
S306
V
C
N
K
K
C
S
S
A
S
S
L
Q
E
H
Site 37
S309
K
K
C
S
S
A
S
S
L
Q
E
H
R
K
I
Site 38
S331
E
C
M
K
K
F
I
S
A
N
Q
L
K
R
H
Site 39
Y348
T
H
S
E
K
R
P
Y
N
C
E
I
C
N
K
Site 40
Y376
I
H
S
E
D
K
P
Y
K
C
K
L
C
G
K
Site 41
Y391
G
F
A
H
R
N
V
Y
K
N
H
K
K
T
H
Site 42
S399
K
N
H
K
K
T
H
S
E
E
R
P
F
Q
C
Site 43
T415
E
C
K
A
L
F
R
T
P
F
S
L
Q
R
H
Site 44
T446
A
T
F
K
R
K
D
T
L
N
V
H
V
Q
V
Site 45
Y461
V
H
E
R
H
K
K
Y
R
C
E
L
C
N
K
Site 46
S474
N
K
A
F
V
T
P
S
V
L
R
S
H
K
K
Site 47
S478
V
T
P
S
V
L
R
S
H
K
K
T
H
T
G
Site 48
T482
V
L
R
S
H
K
K
T
H
T
G
E
K
E
K
Site 49
Y493
E
K
E
K
I
C
P
Y
C
G
Q
K
F
A
S
Site 50
S501
C
G
Q
K
F
A
S
S
G
T
L
R
V
H
I
Site 51
T503
Q
K
F
A
S
S
G
T
L
R
V
H
I
R
S
Site 52
S510
T
L
R
V
H
I
R
S
H
T
G
E
R
P
Y
Site 53
T512
R
V
H
I
R
S
H
T
G
E
R
P
Y
Q
C
Site 54
Y517
S
H
T
G
E
R
P
Y
Q
C
P
Y
C
E
K
Site 55
Y521
E
R
P
Y
Q
C
P
Y
C
E
K
G
F
S
K
Site 56
T540
K
M
H
I
R
T
H
T
R
E
K
P
Y
K
C
Site 57
Y545
T
H
T
R
E
K
P
Y
K
C
S
E
C
S
K
Site 58
S548
R
E
K
P
Y
K
C
S
E
C
S
K
A
F
S
Site 59
S555
S
E
C
S
K
A
F
S
Q
K
R
G
L
D
E
Site 60
T566
G
L
D
E
H
K
R
T
H
T
G
E
K
P
F
Site 61
T568
D
E
H
K
R
T
H
T
G
E
K
P
F
Q
C
Site 62
T612
Q
F
C
H
K
K
F
T
R
N
D
Y
L
K
V
Site 63
Y616
K
K
F
T
R
N
D
Y
L
K
V
H
M
D
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation