PhosphoNET

           
Protein Info 
   
Short Name:  NPDC1
Full Name:  Neural proliferation differentiation and control protein 1
Alias:  CAB-; CAB1; DKFZp586J0523; Neural proliferation differentiation and control protein 1 precursor; Neural proliferation, differentiation and control, 1; NPDC-1
Type:  Tumor suppressor
Mass (Da):  34516
Number AA:  325
UniProt ID:  Q9NQX5
International Prot ID:  IPI00299699
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9ATPLPPPSPRHLRLL
Site 2S111QELARKESGHSTPPL
Site 3S114ARKESGHSTPPLPKD
Site 4T115RKESGHSTPPLPKDR
Site 5T130QRLPEPATLGFSARG
Site 6S134EPATLGFSARGQGLE
Site 7S146GLELGLPSTPGTPTP
Site 8T147LELGLPSTPGTPTPT
Site 9T150GLPSTPGTPTPTPHT
Site 10T152PSTPGTPTPTPHTSL
Site 11T154TPGTPTPTPHTSLGS
Site 12T157TPTPTPHTSLGSPVS
Site 13S158PTPTPHTSLGSPVSS
Site 14S161TPHTSLGSPVSSDPV
Site 15S164TSLGSPVSSDPVHMS
Site 16S165SLGSPVSSDPVHMSP
Site 17S171SSDPVHMSPLEPRGG
Site 18T216LQREIRLTQKADYAT
Site 19Y221RLTQKADYATAKAPG
Site 20S229ATAKAPGSPAAPRIS
Site 21S236SPAAPRISPGDQRLA
Site 22Y249LAQSAEMYHYQHQRQ
Site 23Y251QSAEMYHYQHQRQQM
Site 24T273EPPKELDTASSDEEN
Site 25S275PKELDTASSDEENED
Site 26S276KELDTASSDEENEDG
Site 27T286ENEDGDFTVYECPGL
Site 28Y288EDGDFTVYECPGLAP
Site 29S319SAPLPAPSSPPALP_
Site 30S320APLPAPSSPPALP__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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