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Updated November 2019
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Protein Info
Short Name:
BIRC6
Full Name:
Baculoviral IAP repeat-containing protein 6
Alias:
Apollon; Baculoviral IAP repeat-containing 6; BIR6; BRUCE; KIAA1289; Ubiquitin carrier protein; Ubiquitin-conjugating BIR domain enzyme apollon; Ubiquitin-conjugating BIR-domain enzyme apollon; Ubiquitin-conjugating enzyme E2; Ubiquitin-protein ligase
Type:
Ubiquitin conjugating system
Mass (Da):
527610
Number AA:
4829
UniProt ID:
Q9NR09
International Prot ID:
IPI00299635
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0004869
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0006915
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
C
D
A
D
G
L
H
S
L
S
Y
H
P
A
L
Site 2
S46
A
D
G
L
H
S
L
S
Y
H
P
A
L
N
A
Site 3
Y47
D
G
L
H
S
L
S
Y
H
P
A
L
N
A
I
Site 4
S77
S
G
A
T
L
Q
A
S
A
L
S
A
K
P
G
Site 5
S80
T
L
Q
A
S
A
L
S
A
K
P
G
G
Q
V
Site 6
Y91
G
G
Q
V
K
C
Q
Y
I
S
A
V
D
K
V
Site 7
Y104
K
V
I
F
V
D
D
Y
A
V
G
C
R
K
D
Site 8
T124
L
L
D
T
A
L
Q
T
P
V
S
K
Q
D
D
Site 9
S127
T
A
L
Q
T
P
V
S
K
Q
D
D
V
V
Q
Site 10
S157
L
E
K
V
D
I
S
S
T
E
G
Y
D
L
F
Site 11
Y161
D
I
S
S
T
E
G
Y
D
L
F
I
T
Q
L
Site 12
T166
E
G
Y
D
L
F
I
T
Q
L
K
D
G
L
K
Site 13
S232
S
S
V
M
D
R
L
S
Y
L
L
P
S
A
R
Site 14
Y233
S
V
M
D
R
L
S
Y
L
L
P
S
A
R
P
Site 15
S249
L
G
V
G
P
G
R
S
V
D
R
S
L
M
Y
Site 16
S253
P
G
R
S
V
D
R
S
L
M
Y
S
E
A
N
Site 17
S257
V
D
R
S
L
M
Y
S
E
A
N
R
R
E
T
Site 18
T264
S
E
A
N
R
R
E
T
F
T
S
W
P
H
V
Site 19
T266
A
N
R
R
E
T
F
T
S
W
P
H
V
G
Y
Site 20
Y273
T
S
W
P
H
V
G
Y
R
W
A
Q
P
D
P
Site 21
Y287
P
M
A
Q
A
G
F
Y
H
Q
P
A
S
S
G
Site 22
S292
G
F
Y
H
Q
P
A
S
S
G
D
D
R
A
M
Site 23
S318
E
P
T
D
E
P
W
S
E
H
E
R
H
S
P
Site 24
T335
P
F
V
K
G
E
H
T
Q
N
V
P
L
S
V
Site 25
S341
H
T
Q
N
V
P
L
S
V
T
L
A
T
S
P
Site 26
T354
S
P
A
Q
F
P
C
T
D
G
T
D
R
I
S
Site 27
S361
T
D
G
T
D
R
I
S
C
F
G
S
G
S
C
Site 28
S365
D
R
I
S
C
F
G
S
G
S
C
P
H
F
L
Site 29
Y401
L
K
F
E
I
N
A
Y
D
P
A
I
V
Q
Q
Site 30
S416
L
I
L
S
G
D
P
S
S
G
V
D
S
R
R
Site 31
S417
I
L
S
G
D
P
S
S
G
V
D
S
R
R
P
Site 32
S421
D
P
S
S
G
V
D
S
R
R
P
T
L
A
W
Site 33
T425
G
V
D
S
R
R
P
T
L
A
W
L
E
D
S
Site 34
S432
T
L
A
W
L
E
D
S
S
S
C
S
D
I
P
Site 35
S434
A
W
L
E
D
S
S
S
C
S
D
I
P
K
L
Site 36
S436
L
E
D
S
S
S
C
S
D
I
P
K
L
E
G
Site 37
S445
I
P
K
L
E
G
D
S
D
D
L
L
E
D
S
Site 38
S452
S
D
D
L
L
E
D
S
D
S
E
E
H
S
R
Site 39
S454
D
L
L
E
D
S
D
S
E
E
H
S
R
S
D
Site 40
S458
D
S
D
S
E
E
H
S
R
S
D
S
V
T
G
Site 41
S460
D
S
E
E
H
S
R
S
D
S
V
T
G
H
T
Site 42
S462
E
E
H
S
R
S
D
S
V
T
G
H
T
S
Q
Site 43
T464
H
S
R
S
D
S
V
T
G
H
T
S
Q
K
E
Site 44
S468
D
S
V
T
G
H
T
S
Q
K
E
A
M
E
V
Site 45
S476
Q
K
E
A
M
E
V
S
L
D
I
T
A
L
S
Site 46
T480
M
E
V
S
L
D
I
T
A
L
S
I
L
Q
Q
Site 47
S483
S
L
D
I
T
A
L
S
I
L
Q
Q
P
E
K
Site 48
T503
V
A
N
V
L
E
D
T
V
K
D
L
E
E
L
Site 49
T517
L
G
A
N
P
C
L
T
N
S
K
S
E
K
T
Site 50
S519
A
N
P
C
L
T
N
S
K
S
E
K
T
K
E
Site 51
S521
P
C
L
T
N
S
K
S
E
K
T
K
E
K
H
Site 52
S549
G
G
L
L
T
Y
K
S
P
A
T
S
P
I
S
Site 53
T552
L
T
Y
K
S
P
A
T
S
P
I
S
S
N
S
Site 54
S553
T
Y
K
S
P
A
T
S
P
I
S
S
N
S
H
Site 55
S556
S
P
A
T
S
P
I
S
S
N
S
H
R
S
L
Site 56
S557
P
A
T
S
P
I
S
S
N
S
H
R
S
L
D
Site 57
S559
T
S
P
I
S
S
N
S
H
R
S
L
D
G
L
Site 58
S562
I
S
S
N
S
H
R
S
L
D
G
L
S
R
T
Site 59
S567
H
R
S
L
D
G
L
S
R
T
Q
G
E
S
I
Site 60
T569
S
L
D
G
L
S
R
T
Q
G
E
S
I
S
E
Site 61
S573
L
S
R
T
Q
G
E
S
I
S
E
Q
G
S
T
Site 62
S575
R
T
Q
G
E
S
I
S
E
Q
G
S
T
D
N
Site 63
S579
E
S
I
S
E
Q
G
S
T
D
N
E
S
C
T
Site 64
T580
S
I
S
E
Q
G
S
T
D
N
E
S
C
T
N
Site 65
S584
Q
G
S
T
D
N
E
S
C
T
N
S
E
L
N
Site 66
T586
S
T
D
N
E
S
C
T
N
S
E
L
N
S
P
Site 67
S588
D
N
E
S
C
T
N
S
E
L
N
S
P
L
V
Site 68
S592
C
T
N
S
E
L
N
S
P
L
V
R
R
T
L
Site 69
S606
L
P
V
L
L
L
Y
S
I
K
E
S
D
E
K
Site 70
S610
L
L
Y
S
I
K
E
S
D
E
K
A
G
K
I
Site 71
S619
E
K
A
G
K
I
F
S
Q
M
N
N
I
M
S
Site 72
S626
S
Q
M
N
N
I
M
S
K
S
L
H
D
D
G
Site 73
T635
S
L
H
D
D
G
F
T
V
P
Q
I
I
E
M
Site 74
S646
I
I
E
M
E
L
D
S
Q
E
Q
L
L
L
Q
Site 75
T671
A
D
A
A
A
N
L
T
S
P
D
S
E
K
W
Site 76
S672
D
A
A
A
N
L
T
S
P
D
S
E
K
W
N
Site 77
S675
A
N
L
T
S
P
D
S
E
K
W
N
S
V
F
Site 78
S680
P
D
S
E
K
W
N
S
V
F
P
K
P
G
T
Site 79
S707
E
E
N
L
C
I
D
S
I
T
P
C
A
D
G
Site 80
S746
N
N
L
N
K
L
N
S
A
L
C
N
R
R
K
Site 81
S775
I
S
V
I
Q
H
E
S
P
A
D
V
Q
T
P
Site 82
T781
E
S
P
A
D
V
Q
T
P
L
I
I
Q
P
E
Site 83
S793
Q
P
E
Q
R
N
V
S
G
G
Y
L
V
L
Y
Site 84
Y800
S
G
G
Y
L
V
L
Y
K
M
N
Y
A
T
R
Site 85
T810
N
Y
A
T
R
I
V
T
L
E
E
E
P
I
K
Site 86
T829
K
D
P
Q
D
T
I
T
S
L
I
L
L
P
P
Site 87
T866
N
G
F
E
R
E
K
T
S
D
I
S
T
L
G
Site 88
S867
G
F
E
R
E
K
T
S
D
I
S
T
L
G
H
Site 89
S870
R
E
K
T
S
D
I
S
T
L
G
H
L
V
I
Site 90
T911
E
G
T
E
E
Q
D
T
F
V
S
V
I
Y
C
Site 91
T928
T
D
R
L
C
A
C
T
K
G
G
E
L
H
F
Site 92
S963
L
S
K
G
I
E
P
S
S
E
G
S
K
P
L
Site 93
S964
S
K
G
I
E
P
S
S
E
G
S
K
P
L
S
Site 94
S967
I
E
P
S
S
E
G
S
K
P
L
S
N
P
S
Site 95
S971
S
E
G
S
K
P
L
S
N
P
S
S
P
G
I
Site 96
S974
S
K
P
L
S
N
P
S
S
P
G
I
S
G
V
Site 97
S975
K
P
L
S
N
P
S
S
P
G
I
S
G
V
D
Site 98
T1005
V
E
L
T
R
F
E
T
L
T
P
R
F
S
A
Site 99
S1011
E
T
L
T
P
R
F
S
A
T
V
P
P
C
W
Site 100
T1053
T
R
T
W
K
L
Q
T
D
S
N
S
W
D
E
Site 101
S1057
K
L
Q
T
D
S
N
S
W
D
E
H
V
F
E
Site 102
Y1189
K
G
M
A
G
G
K
Y
R
S
F
L
I
H
V
Site 103
T1204
K
A
V
N
E
R
G
T
E
E
I
C
N
G
G
Site 104
S1220
R
P
V
V
R
L
P
S
L
K
H
Q
S
N
K
Site 105
Y1229
K
H
Q
S
N
K
G
Y
S
L
A
S
L
L
A
Site 106
S1230
H
Q
S
N
K
G
Y
S
L
A
S
L
L
A
K
Site 107
S1245
V
A
A
G
K
E
K
S
S
N
V
K
N
E
N
Site 108
S1254
N
V
K
N
E
N
T
S
G
T
R
K
S
E
N
Site 109
S1259
N
T
S
G
T
R
K
S
E
N
L
R
G
C
D
Site 110
S1272
C
D
L
L
Q
E
V
S
V
T
I
R
R
F
K
Site 111
T1274
L
L
Q
E
V
S
V
T
I
R
R
F
K
K
T
Site 112
T1281
T
I
R
R
F
K
K
T
S
I
S
K
E
R
V
Site 113
S1282
I
R
R
F
K
K
T
S
I
S
K
E
R
V
Q
Site 114
S1284
R
F
K
K
T
S
I
S
K
E
R
V
Q
R
C
Site 115
T1306
F
H
E
K
L
L
N
T
L
C
R
K
T
D
D
Site 116
T1311
L
N
T
L
C
R
K
T
D
D
G
Q
I
T
E
Site 117
S1336
C
W
L
A
G
V
H
S
N
G
P
G
S
S
K
Site 118
S1341
V
H
S
N
G
P
G
S
S
K
E
G
N
E
N
Site 119
S1351
E
G
N
E
N
L
L
S
K
T
R
K
F
L
S
Site 120
S1450
A
S
L
L
T
A
V
S
R
Q
L
Q
D
R
L
Site 121
T1458
R
Q
L
Q
D
R
L
T
P
M
E
A
L
L
Q
Site 122
Y1468
E
A
L
L
Q
T
R
Y
G
L
Y
S
S
P
F
Site 123
Y1471
L
Q
T
R
Y
G
L
Y
S
S
P
F
D
P
V
Site 124
S1472
Q
T
R
Y
G
L
Y
S
S
P
F
D
P
V
L
Site 125
S1473
T
R
Y
G
L
Y
S
S
P
F
D
P
V
L
F
Site 126
S1487
F
D
L
E
M
S
G
S
S
C
K
N
V
Y
N
Site 127
Y1493
G
S
S
C
K
N
V
Y
N
S
S
I
G
V
Q
Site 128
S1495
S
C
K
N
V
Y
N
S
S
I
G
V
Q
S
D
Site 129
S1496
C
K
N
V
Y
N
S
S
I
G
V
Q
S
D
E
Site 130
S1501
N
S
S
I
G
V
Q
S
D
E
I
D
L
S
D
Site 131
S1507
Q
S
D
E
I
D
L
S
D
V
L
S
G
N
G
Site 132
S1511
I
D
L
S
D
V
L
S
G
N
G
K
V
S
S
Site 133
S1517
L
S
G
N
G
K
V
S
S
C
T
A
A
E
G
Site 134
S1518
S
G
N
G
K
V
S
S
C
T
A
A
E
G
S
Site 135
S1544
P
L
H
F
T
C
V
S
T
S
D
G
T
R
I
Site 136
S1558
I
E
R
D
D
A
M
S
S
F
G
V
T
P
A
Site 137
S1559
E
R
D
D
A
M
S
S
F
G
V
T
P
A
V
Site 138
S1650
P
V
H
N
S
V
P
S
N
P
V
A
A
P
G
Site 139
T1669
P
S
D
V
I
P
P
T
P
K
T
T
P
L
F
Site 140
T1672
V
I
P
P
T
P
K
T
T
P
L
F
M
T
P
Site 141
T1673
I
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S
A
A
Site 293
S3714
Q
T
S
A
R
S
A
S
L
S
S
A
A
T
T
Site 294
S3716
S
A
R
S
A
S
L
S
S
A
A
T
T
G
L
Site 295
T3720
A
S
L
S
S
A
A
T
T
G
L
T
T
Q
Q
Site 296
T3721
S
L
S
S
A
A
T
T
G
L
T
T
Q
Q
R
Site 297
T3763
V
L
C
E
L
F
Q
T
S
P
Q
R
G
N
L
Site 298
S3764
L
C
E
L
F
Q
T
S
P
Q
R
G
N
L
P
Site 299
T3772
P
Q
R
G
N
L
P
T
S
G
N
I
S
G
F
Site 300
S3773
Q
R
G
N
L
P
T
S
G
N
I
S
G
F
I
Site 301
S3800
K
V
T
M
F
L
Q
S
P
C
P
L
Y
K
G
Site 302
Y3805
L
Q
S
P
C
P
L
Y
K
G
R
I
N
A
T
Site 303
Y3821
H
V
I
Q
H
P
M
Y
G
A
G
H
K
F
R
Site 304
S3846
S
D
V
L
D
R
V
S
D
T
P
S
I
T
A
Site 305
S3850
D
R
V
S
D
T
P
S
I
T
A
K
L
I
S
Site 306
S3857
S
I
T
A
K
L
I
S
E
Q
K
D
D
K
E
Site 307
Y3884
E
N
G
F
Q
D
N
Y
S
V
V
V
A
S
G
Site 308
S3890
N
Y
S
V
V
V
A
S
G
L
K
S
Q
S
K
Site 309
S3894
V
V
A
S
G
L
K
S
Q
S
K
R
A
V
S
Site 310
S3896
A
S
G
L
K
S
Q
S
K
R
A
V
S
A
T
Site 311
S3901
S
Q
S
K
R
A
V
S
A
T
P
P
R
P
P
Site 312
T3903
S
K
R
A
V
S
A
T
P
P
R
P
P
S
R
Site 313
S3909
A
T
P
P
R
P
P
S
R
R
G
R
T
I
P
Site 314
T3914
P
P
S
R
R
G
R
T
I
P
D
K
I
G
S
Site 315
Y3963
A
Q
L
L
T
L
L
Y
D
R
K
L
P
Q
G
Site 316
T3977
G
Y
R
S
I
D
L
T
V
K
L
G
S
R
V
Site 317
T3986
K
L
G
S
R
V
I
T
D
P
S
L
S
K
T
Site 318
S3989
S
R
V
I
T
D
P
S
L
S
K
T
D
S
Y
Site 319
S3991
V
I
T
D
P
S
L
S
K
T
D
S
Y
K
R
Site 320
T3993
T
D
P
S
L
S
K
T
D
S
Y
K
R
L
H
Site 321
S3995
P
S
L
S
K
T
D
S
Y
K
R
L
H
P
E
Site 322
Y3996
S
L
S
K
T
D
S
Y
K
R
L
H
P
E
K
Site 323
S4011
D
H
G
D
L
L
A
S
C
P
E
D
E
A
L
Site 324
T4019
C
P
E
D
E
A
L
T
P
G
D
E
C
M
D
Site 325
T4078
S
A
P
V
V
T
S
T
T
Q
E
K
P
K
D
Site 326
S4086
T
Q
E
K
P
K
D
S
D
Q
F
E
W
V
T
Site 327
T4093
S
D
Q
F
E
W
V
T
I
E
Q
S
G
E
L
Site 328
Y4102
E
Q
S
G
E
L
V
Y
E
A
P
E
T
V
A
Site 329
T4107
L
V
Y
E
A
P
E
T
V
A
A
E
P
P
P
Site 330
S4117
A
E
P
P
P
I
K
S
A
V
Q
T
M
S
P
Site 331
T4121
P
I
K
S
A
V
Q
T
M
S
P
I
P
A
H
Site 332
S4123
K
S
A
V
Q
T
M
S
P
I
P
A
H
S
L
Site 333
T4164
L
R
L
V
L
G
V
T
D
D
G
E
G
S
H
Site 334
S4175
E
G
S
H
I
L
Q
S
P
S
A
N
V
L
P
Site 335
S4194
H
V
L
R
S
L
F
S
T
T
P
L
T
T
D
Site 336
T4195
V
L
R
S
L
F
S
T
T
P
L
T
T
D
D
Site 337
T4196
L
R
S
L
F
S
T
T
P
L
T
T
D
D
G
Site 338
S4230
L
S
A
L
S
H
H
S
P
R
V
P
N
S
S
Site 339
S4236
H
S
P
R
V
P
N
S
S
V
N
Q
T
E
P
Site 340
S4237
S
P
R
V
P
N
S
S
V
N
Q
T
E
P
Q
Site 341
T4241
P
N
S
S
V
N
Q
T
E
P
Q
V
S
S
S
Site 342
S4246
N
Q
T
E
P
Q
V
S
S
S
H
N
P
T
S
Site 343
S4248
T
E
P
Q
V
S
S
S
H
N
P
T
S
T
E
Site 344
T4252
V
S
S
S
H
N
P
T
S
T
E
E
Q
Q
L
Site 345
S4253
S
S
S
H
N
P
T
S
T
E
E
Q
Q
L
Y
Site 346
T4254
S
S
H
N
P
T
S
T
E
E
Q
Q
L
Y
W
Site 347
Y4260
S
T
E
E
Q
Q
L
Y
W
A
K
G
T
G
F
Site 348
T4269
A
K
G
T
G
F
G
T
G
S
T
A
S
G
W
Site 349
S4271
G
T
G
F
G
T
G
S
T
A
S
G
W
D
V
Site 350
T4283
W
D
V
E
Q
A
L
T
K
Q
R
L
E
E
E
Site 351
S4307
A
S
Y
I
N
P
V
S
S
A
V
N
G
E
A
Site 352
S4308
S
Y
I
N
P
V
S
S
A
V
N
G
E
A
Q
Site 353
S4317
V
N
G
E
A
Q
S
S
H
E
T
R
G
Q
N
Site 354
S4346
S
C
L
I
P
A
M
S
S
Y
L
R
N
D
S
Site 355
S4353
S
S
Y
L
R
N
D
S
V
L
D
M
A
R
H
Site 356
S4388
V
P
L
L
L
P
L
S
T
E
N
G
E
E
E
Site 357
S4399
G
E
E
E
E
E
Q
S
E
C
Q
T
S
V
G
Site 358
T4403
E
E
Q
S
E
C
Q
T
S
V
G
T
L
L
A
Site 359
S4404
E
Q
S
E
C
Q
T
S
V
G
T
L
L
A
K
Site 360
T4414
T
L
L
A
K
M
K
T
C
V
D
T
Y
T
N
Site 361
T4418
K
M
K
T
C
V
D
T
Y
T
N
R
L
R
S
Site 362
Y4419
M
K
T
C
V
D
T
Y
T
N
R
L
R
S
K
Site 363
T4420
K
T
C
V
D
T
Y
T
N
R
L
R
S
K
R
Site 364
S4425
T
Y
T
N
R
L
R
S
K
R
E
N
V
K
T
Site 365
T4432
S
K
R
E
N
V
K
T
G
V
K
P
D
A
S
Site 366
S4439
T
G
V
K
P
D
A
S
D
Q
E
P
E
G
L
Site 367
Y4461
Q
K
T
A
E
I
V
Y
A
A
T
T
S
L
R
Site 368
S4466
I
V
Y
A
A
T
T
S
L
R
Q
A
N
Q
E
Site 369
S4491
A
M
K
P
K
P
L
S
V
L
K
S
L
E
E
Site 370
S4495
K
P
L
S
V
L
K
S
L
E
E
K
Y
V
A
Site 371
Y4500
L
K
S
L
E
E
K
Y
V
A
V
M
K
K
L
Site 372
T4511
M
K
K
L
Q
F
D
T
F
E
M
V
S
E
D
Site 373
Y4529
K
L
G
F
K
V
N
Y
H
Y
M
S
Q
V
K
Site 374
Y4531
G
F
K
V
N
Y
H
Y
M
S
Q
V
K
N
A
Site 375
S4543
K
N
A
N
D
A
N
S
A
A
R
A
R
R
L
Site 376
S4568
L
P
L
S
S
S
S
S
V
F
V
R
C
D
E
Site 377
Y4593
T
G
P
A
D
T
P
Y
A
N
G
C
F
E
F
Site 378
Y4603
G
C
F
E
F
D
V
Y
F
P
Q
D
Y
P
S
Site 379
Y4608
D
V
Y
F
P
Q
D
Y
P
S
S
P
P
L
V
Site 380
S4610
Y
F
P
Q
D
Y
P
S
S
P
P
L
V
N
L
Site 381
S4611
F
P
Q
D
Y
P
S
S
P
P
L
V
N
L
E
Site 382
T4619
P
P
L
V
N
L
E
T
T
G
G
H
S
V
R
Site 383
S4624
L
E
T
T
G
G
H
S
V
R
F
N
P
N
L
Site 384
Y4632
V
R
F
N
P
N
L
Y
N
D
G
K
V
C
L
Site 385
T4644
V
C
L
S
I
L
N
T
W
H
G
R
P
E
E
Site 386
S4659
K
W
N
P
Q
T
S
S
F
L
Q
V
L
V
S
Site 387
Y4683
P
Y
F
N
E
P
G
Y
E
R
S
R
G
T
P
Site 388
T4689
G
Y
E
R
S
R
G
T
P
S
G
T
Q
S
S
Site 389
S4691
E
R
S
R
G
T
P
S
G
T
Q
S
S
R
E
Site 390
T4693
S
R
G
T
P
S
G
T
Q
S
S
R
E
Y
D
Site 391
S4695
G
T
P
S
G
T
Q
S
S
R
E
Y
D
G
N
Site 392
Y4699
G
T
Q
S
S
R
E
Y
D
G
N
I
R
Q
A
Site 393
T4707
D
G
N
I
R
Q
A
T
V
K
W
A
M
L
E
Site 394
S4720
L
E
Q
I
R
N
P
S
P
C
F
K
E
V
I
Site 395
Y4732
E
V
I
H
K
H
F
Y
L
K
R
V
E
I
M
Site 396
S4754
A
D
I
Q
Q
Y
S
S
D
K
R
V
G
R
T
Site 397
S4763
K
R
V
G
R
T
M
S
H
H
A
A
A
L
K
Site 398
T4773
A
A
A
L
K
R
H
T
A
Q
L
R
E
E
L
Site 399
T4793
P
E
G
L
D
P
D
T
D
D
A
P
E
V
C
Site 400
T4803
A
P
E
V
C
R
A
T
T
G
A
E
E
T
L
Site 401
T4804
P
E
V
C
R
A
T
T
G
A
E
E
T
L
M
Site 402
S4818
M
H
D
Q
V
K
P
S
S
S
K
E
L
P
S
Site 403
S4819
H
D
Q
V
K
P
S
S
S
K
E
L
P
S
D
Site 404
S4820
D
Q
V
K
P
S
S
S
K
E
L
P
S
D
F
Site 405
S4825
S
S
S
K
E
L
P
S
D
F
Q
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation