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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SH3GLB2
Full Name:
Endophilin-B2
Alias:
Endophilin B2; KIAA1848; SH3 domain GRB2-like B2; SH3 domain-containing GRB2-like protein B2; SH3-domain GRB2-like endophilin B2; SHLB2
Type:
Unknown function
Mass (Da):
43974
Number AA:
395
UniProt ID:
Q9NR46
International Prot ID:
IPI00024540
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
F
N
M
K
K
L
A
S
D
A
G
I
F
F
T
Site 2
T23
F
T
R
A
V
Q
F
T
E
E
K
F
G
Q
A
Site 3
S48
N
L
L
A
R
A
D
S
T
K
N
W
T
E
K
Site 4
T60
T
E
K
I
L
R
Q
T
E
V
L
L
Q
P
N
Site 5
Y77
A
R
V
E
E
F
L
Y
E
K
L
D
R
K
V
Site 6
T89
R
K
V
P
S
R
V
T
N
G
E
L
L
A
Q
Site 7
Y97
N
G
E
L
L
A
Q
Y
M
A
D
A
A
S
E
Site 8
S103
Q
Y
M
A
D
A
A
S
E
L
G
P
T
T
P
Site 9
T108
A
A
S
E
L
G
P
T
T
P
Y
G
K
T
L
Site 10
T109
A
S
E
L
G
P
T
T
P
Y
G
K
T
L
I
Site 11
T154
F
L
E
G
D
W
K
T
I
S
K
E
R
R
L
Site 12
S156
E
G
D
W
K
T
I
S
K
E
R
R
L
L
Q
Site 13
T187
K
A
A
E
A
K
A
T
T
V
P
D
F
Q
E
Site 14
Y200
Q
E
T
R
P
R
N
Y
I
L
S
A
S
A
S
Site 15
S203
R
P
R
N
Y
I
L
S
A
S
A
S
A
L
W
Site 16
S205
R
N
Y
I
L
S
A
S
A
S
A
L
W
N
D
Site 17
S207
Y
I
L
S
A
S
A
S
A
L
W
N
D
E
V
Site 18
T262
E
F
V
K
S
Q
T
T
Y
Y
A
Q
C
Y
R
Site 19
Y263
F
V
K
S
Q
T
T
Y
Y
A
Q
C
Y
R
H
Site 20
Y264
V
K
S
Q
T
T
Y
Y
A
Q
C
Y
R
H
M
Site 21
Y268
T
T
Y
Y
A
Q
C
Y
R
H
M
L
D
L
Q
Site 22
T284
Q
L
G
R
F
P
G
T
F
V
G
T
T
E
P
Site 23
T288
F
P
G
T
F
V
G
T
T
E
P
A
S
P
P
Site 24
T289
P
G
T
F
V
G
T
T
E
P
A
S
P
P
L
Site 25
S293
V
G
T
T
E
P
A
S
P
P
L
S
S
T
S
Site 26
S297
E
P
A
S
P
P
L
S
S
T
S
P
T
T
A
Site 27
S298
P
A
S
P
P
L
S
S
T
S
P
T
T
A
A
Site 28
S300
S
P
P
L
S
S
T
S
P
T
T
A
A
A
T
Site 29
T302
P
L
S
S
T
S
P
T
T
A
A
A
T
M
P
Site 30
S335
E
E
V
A
P
P
A
S
G
T
R
K
A
R
V
Site 31
Y344
T
R
K
A
R
V
L
Y
D
Y
E
A
A
D
S
Site 32
Y346
K
A
R
V
L
Y
D
Y
E
A
A
D
S
S
E
Site 33
S351
Y
D
Y
E
A
A
D
S
S
E
L
A
L
L
A
Site 34
S352
D
Y
E
A
A
D
S
S
E
L
A
L
L
A
D
Site 35
S366
D
E
L
I
T
V
Y
S
L
P
G
M
D
P
D
Site 36
T389
K
K
G
K
V
P
V
T
Y
L
E
L
L
S
_
Site 37
S395
V
T
Y
L
E
L
L
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation