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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYP26B1
Full Name:
Cytochrome P450 26B1
Alias:
Cytochrome P450 26A2;Cytochrome P450 retinoic acid-inactivating 2;Retinoic acid-metabolizing cytochrome
Type:
Mass (Da):
57513
Number AA:
512
UniProt ID:
Q9NR63
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
W
A
A
T
R
D
K
S
C
K
L
P
I
P
K
Site 2
S70
G
H
W
L
L
Q
G
S
G
F
Q
S
S
R
R
Site 3
S74
L
Q
G
S
G
F
Q
S
S
R
R
E
K
Y
G
Site 4
S75
Q
G
S
G
F
Q
S
S
R
R
E
K
Y
G
N
Site 5
Y80
Q
S
S
R
R
E
K
Y
G
N
V
F
K
T
H
Site 6
T97
G
R
P
L
I
R
V
T
G
A
E
N
V
R
K
Site 7
T115
G
E
H
H
L
V
S
T
E
W
P
R
S
T
R
Site 8
S120
V
S
T
E
W
P
R
S
T
R
M
L
L
G
P
Site 9
T121
S
T
E
W
P
R
S
T
R
M
L
L
G
P
N
Site 10
T129
R
M
L
L
G
P
N
T
V
S
N
S
I
G
D
Site 11
S133
G
P
N
T
V
S
N
S
I
G
D
I
H
R
N
Site 12
S146
R
N
K
R
K
V
F
S
K
I
F
S
H
E
A
Site 13
S150
K
V
F
S
K
I
F
S
H
E
A
L
E
S
Y
Site 14
S156
F
S
H
E
A
L
E
S
Y
L
P
K
I
Q
L
Site 15
Y157
S
H
E
A
L
E
S
Y
L
P
K
I
Q
L
V
Site 16
T168
I
Q
L
V
I
Q
D
T
L
R
A
W
S
S
H
Site 17
S173
Q
D
T
L
R
A
W
S
S
H
P
E
A
I
N
Site 18
T189
Y
Q
E
A
Q
K
L
T
F
R
M
A
I
R
V
Site 19
S231
L
P
V
D
L
P
F
S
G
Y
R
R
G
I
Q
Site 20
Y233
V
D
L
P
F
S
G
Y
R
R
G
I
Q
A
R
Site 21
Y263
Q
C
T
Q
G
K
D
Y
L
D
A
L
D
L
L
Site 22
S274
L
D
L
L
I
E
S
S
K
E
H
G
K
E
M
Site 23
T290
M
Q
E
L
K
D
G
T
L
E
L
I
F
A
A
Site 24
Y298
L
E
L
I
F
A
A
Y
A
T
T
A
S
A
S
Site 25
T317
M
Q
L
L
K
H
P
T
V
L
E
K
L
R
D
Site 26
S334
R
A
H
G
I
L
H
S
G
G
C
P
C
E
G
Site 27
T342
G
G
C
P
C
E
G
T
L
R
L
D
T
L
S
Site 28
T347
E
G
T
L
R
L
D
T
L
S
G
L
R
Y
L
Site 29
Y353
D
T
L
S
G
L
R
Y
L
D
C
V
I
K
E
Site 30
T366
K
E
V
M
R
L
F
T
P
I
S
G
G
Y
R
Site 31
T378
G
Y
R
T
V
L
Q
T
F
E
L
D
G
F
Q
Site 32
Y394
P
K
G
W
S
V
M
Y
S
I
R
D
T
H
D
Site 33
T399
V
M
Y
S
I
R
D
T
H
D
T
A
P
V
F
Site 34
T402
S
I
R
D
T
H
D
T
A
P
V
F
K
D
V
Site 35
S418
V
F
D
P
D
R
F
S
Q
A
R
S
E
D
K
Site 36
S422
D
R
F
S
Q
A
R
S
E
D
K
D
G
R
F
Site 37
Y431
D
K
D
G
R
F
H
Y
L
P
F
G
G
G
V
Site 38
S495
V
K
F
F
G
L
D
S
N
Q
N
E
I
L
P
Site 39
T504
Q
N
E
I
L
P
E
T
E
A
M
L
S
A
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation