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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SIRT7
Full Name:
NAD-dependent deacetylase sirtuin-7
Alias:
SIR2-like protein 7
Type:
Mass (Da):
44898
Number AA:
400
UniProt ID:
Q9NRC8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
A
G
G
L
S
R
S
E
R
K
A
A
E
R
Site 2
S33
R
E
R
L
R
Q
V
S
R
I
L
R
K
A
A
Site 3
S65
V
T
E
L
Q
G
R
S
R
R
R
E
G
L
K
Site 4
S94
G
K
V
R
E
L
A
S
A
V
R
N
A
K
Y
Site 5
S115
A
G
I
S
T
A
A
S
I
P
D
Y
R
G
P
Site 6
Y119
T
A
A
S
I
P
D
Y
R
G
P
N
G
V
W
Site 7
T127
R
G
P
N
G
V
W
T
L
L
Q
K
G
R
S
Site 8
S134
T
L
L
Q
K
G
R
S
V
S
A
A
D
L
S
Site 9
S136
L
Q
K
G
R
S
V
S
A
A
D
L
S
E
A
Site 10
S141
S
V
S
A
A
D
L
S
E
A
E
P
T
L
T
Site 11
T146
D
L
S
E
A
E
P
T
L
T
H
M
S
I
T
Site 12
T148
S
E
A
E
P
T
L
T
H
M
S
I
T
R
L
Site 13
S151
E
P
T
L
T
H
M
S
I
T
R
L
H
E
Q
Site 14
S166
K
L
V
Q
H
V
V
S
Q
N
C
D
G
L
H
Site 15
T181
L
R
S
G
L
P
R
T
A
I
S
E
L
H
G
Site 16
S184
G
L
P
R
T
A
I
S
E
L
H
G
N
M
Y
Site 17
Y191
S
E
L
H
G
N
M
Y
I
E
V
C
T
S
C
Site 18
Y204
S
C
V
P
N
R
E
Y
V
R
V
F
D
V
T
Site 19
T211
Y
V
R
V
F
D
V
T
E
R
T
A
L
H
R
Site 20
T221
T
A
L
H
R
H
Q
T
G
R
T
C
H
K
C
Site 21
T235
C
G
T
Q
L
R
D
T
I
V
H
F
G
E
R
Site 22
T244
V
H
F
G
E
R
G
T
L
G
Q
P
L
N
W
Site 23
Y277
S
L
K
V
L
K
K
Y
P
R
L
W
C
M
T
Site 24
T284
Y
P
R
L
W
C
M
T
K
P
P
S
R
R
P
Site 25
Y294
P
S
R
R
P
K
L
Y
I
V
N
L
Q
W
T
Site 26
Y333
L
G
L
E
I
P
A
Y
S
R
W
Q
D
P
I
Site 27
S342
R
W
Q
D
P
I
F
S
L
A
T
P
L
R
A
Site 28
T345
D
P
I
F
S
L
A
T
P
L
R
A
G
E
E
Site 29
S354
L
R
A
G
E
E
G
S
H
S
R
K
S
L
C
Site 30
S356
A
G
E
E
G
S
H
S
R
K
S
L
C
R
S
Site 31
S359
E
G
S
H
S
R
K
S
L
C
R
S
R
E
E
Site 32
S363
S
R
K
S
L
C
R
S
R
E
E
A
P
P
G
Site 33
S377
G
D
R
G
A
P
L
S
S
A
P
I
L
G
G
Site 34
S378
D
R
G
A
P
L
S
S
A
P
I
L
G
G
W
Site 35
T391
G
W
F
G
R
G
C
T
K
R
T
K
R
K
K
Site 36
T394
G
R
G
C
T
K
R
T
K
R
K
K
V
T
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation