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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CTPS2
Full Name:
CTP synthase 2
Alias:
CTP synthetase 2; EC 6.3.4.2; PYRG2; UTP-ammonia ligase 2
Type:
Uncharacterized protein
Mass (Da):
65678
Number AA:
586
UniProt ID:
Q9NRF8
International Prot ID:
IPI00645702
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003883
PhosphoSite+
KinaseNET
Biological Process:
GO:0006541
GO:0006221
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T35
K
S
C
G
L
R
V
T
A
I
K
I
D
P
Y
Site 2
T49
Y
I
N
I
D
A
G
T
F
S
P
Y
E
H
G
Site 3
S51
N
I
D
A
G
T
F
S
P
Y
E
H
G
E
V
Site 4
Y53
D
A
G
T
F
S
P
Y
E
H
G
E
V
F
V
Site 5
Y74
V
D
L
D
L
G
N
Y
E
R
F
L
D
I
N
Site 6
Y83
R
F
L
D
I
N
L
Y
K
D
N
N
I
T
T
Site 7
Y94
N
I
T
T
G
K
I
Y
Q
H
V
I
N
K
E
Site 8
Y106
N
K
E
R
R
G
D
Y
L
G
K
T
V
Q
V
Site 9
T110
R
G
D
Y
L
G
K
T
V
Q
V
V
P
H
I
Site 10
S187
V
S
L
V
P
Q
L
S
A
T
G
E
Q
K
T
Site 11
S200
K
T
K
P
T
Q
N
S
V
R
A
L
R
G
L
Site 12
S261
P
V
L
L
E
E
Q
S
I
V
K
Y
F
K
E
Site 13
Y265
E
E
Q
S
I
V
K
Y
F
K
E
R
L
H
L
Site 14
S279
L
P
I
G
D
S
A
S
N
L
L
F
K
W
R
Site 15
Y292
W
R
N
M
A
D
R
Y
E
R
L
Q
K
I
C
Site 16
Y307
S
I
A
L
V
G
K
Y
T
K
L
R
D
C
Y
Site 17
Y314
Y
T
K
L
R
D
C
Y
A
S
V
F
K
A
L
Site 18
S316
K
L
R
D
C
Y
A
S
V
F
K
A
L
E
H
Site 19
Y336
N
H
K
L
N
L
M
Y
I
D
S
I
D
L
E
Site 20
T348
D
L
E
K
I
T
E
T
E
D
P
V
K
F
H
Site 21
S386
L
G
K
L
Q
A
I
S
W
A
R
T
K
K
I
Site 22
T390
Q
A
I
S
W
A
R
T
K
K
I
P
F
L
G
Site 23
S421
L
N
L
K
D
A
D
S
T
E
F
R
P
N
A
Site 24
T455
M
R
L
G
I
R
R
T
V
F
K
T
E
N
S
Site 25
T459
I
R
R
T
V
F
K
T
E
N
S
I
L
R
K
Site 26
S462
T
V
F
K
T
E
N
S
I
L
R
K
L
Y
G
Site 27
Y468
N
S
I
L
R
K
L
Y
G
D
V
P
F
I
E
Site 28
S498
Q
F
E
Q
N
D
L
S
F
V
G
Q
D
V
D
Site 29
S530
V
Q
F
H
P
E
F
S
S
R
P
M
K
P
S
Site 30
S531
Q
F
H
P
E
F
S
S
R
P
M
K
P
S
P
Site 31
S537
S
S
R
P
M
K
P
S
P
P
Y
L
G
L
L
Site 32
Y554
A
T
G
N
L
N
A
Y
L
Q
Q
G
C
K
L
Site 33
S562
L
Q
Q
G
C
K
L
S
S
S
D
R
Y
S
D
Site 34
S563
Q
Q
G
C
K
L
S
S
S
D
R
Y
S
D
A
Site 35
S564
Q
G
C
K
L
S
S
S
D
R
Y
S
D
A
S
Site 36
Y567
K
L
S
S
S
D
R
Y
S
D
A
S
D
D
S
Site 37
S568
L
S
S
S
D
R
Y
S
D
A
S
D
D
S
F
Site 38
S571
S
D
R
Y
S
D
A
S
D
D
S
F
S
E
P
Site 39
S574
Y
S
D
A
S
D
D
S
F
S
E
P
R
I
A
Site 40
S576
D
A
S
D
D
S
F
S
E
P
R
I
A
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation