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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF277
Full Name:
Zinc finger protein 277
Alias:
Nuclear receptor-interacting factor 4
Type:
Mass (Da):
52788
Number AA:
450
UniProt ID:
Q9NRM2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
A
A
S
K
T
Q
G
A
V
A
Site 2
S20
M
Q
E
D
R
D
G
S
C
S
T
V
G
G
V
Site 3
S22
E
D
R
D
G
S
C
S
T
V
G
G
V
G
Y
Site 4
T23
D
R
D
G
S
C
S
T
V
G
G
V
G
Y
G
Site 5
S32
G
G
V
G
Y
G
D
S
K
D
C
I
L
E
P
Site 6
S41
D
C
I
L
E
P
L
S
L
P
E
S
P
G
G
Site 7
S45
E
P
L
S
L
P
E
S
P
G
G
T
T
T
L
Site 8
T49
L
P
E
S
P
G
G
T
T
T
L
E
G
S
P
Site 9
T51
E
S
P
G
G
T
T
T
L
E
G
S
P
S
V
Site 10
Y102
D
F
Q
R
Y
I
L
Y
W
R
K
R
F
T
E
Site 11
T113
R
F
T
E
Q
P
I
T
D
F
C
S
V
I
R
Site 12
S123
C
S
V
I
R
I
N
S
T
A
P
F
E
E
Q
Site 13
Y133
P
F
E
E
Q
E
N
Y
F
L
L
C
D
V
L
Site 14
Y228
L
D
N
L
Q
C
L
Y
C
E
K
T
F
R
D
Site 15
T238
K
T
F
R
D
K
N
T
L
K
D
H
M
R
K
Site 16
Y258
I
N
P
K
N
R
E
Y
D
R
F
Y
V
I
N
Site 17
Y262
N
R
E
Y
D
R
F
Y
V
I
N
Y
L
E
L
Site 18
Y266
D
R
F
Y
V
I
N
Y
L
E
L
G
K
S
W
Site 19
S272
N
Y
L
E
L
G
K
S
W
E
E
V
Q
L
E
Site 20
Y318
A
E
T
I
E
K
L
Y
V
H
M
E
D
A
H
Site 21
Y341
S
E
L
G
L
N
F
Y
Q
Q
V
K
L
V
N
Site 22
S368
G
C
H
V
K
F
K
S
K
A
D
L
R
T
H
Site 23
T390
S
L
L
P
D
R
K
T
W
D
Q
L
E
Y
Y
Site 24
Y396
K
T
W
D
Q
L
E
Y
Y
F
P
T
Y
E
N
Site 25
Y397
T
W
D
Q
L
E
Y
Y
F
P
T
Y
E
N
D
Site 26
Y401
L
E
Y
Y
F
P
T
Y
E
N
D
T
L
L
C
Site 27
T405
F
P
T
Y
E
N
D
T
L
L
C
T
L
S
D
Site 28
T409
E
N
D
T
L
L
C
T
L
S
D
S
E
S
D
Site 29
S411
D
T
L
L
C
T
L
S
D
S
E
S
D
L
T
Site 30
S413
L
L
C
T
L
S
D
S
E
S
D
L
T
A
Q
Site 31
S415
C
T
L
S
D
S
E
S
D
L
T
A
Q
E
Q
Site 32
T418
S
D
S
E
S
D
L
T
A
Q
E
Q
N
E
N
Site 33
S430
N
E
N
V
P
I
I
S
E
D
T
S
K
L
Y
Site 34
S434
P
I
I
S
E
D
T
S
K
L
Y
A
L
K
Q
Site 35
Y437
S
E
D
T
S
K
L
Y
A
L
K
Q
S
S
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation