KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RASSF1
Full Name:
Ras association domain-containing protein 1
Alias:
123F2; NORE2A; Ras association (RalGDS/AF-6) domain family member 1; RASF1; RDA32; REH3P21
Type:
Tumor suppressor
Mass (Da):
39220
Number AA:
UniProt ID:
Q9NS23
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005874
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007265
GO:0007050
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
G
E
P
E
L
I
E
Site 2
T38
A
L
R
I
A
R
G
T
A
C
N
P
T
R
Q
Site 3
T121
E
P
A
V
E
R
D
T
N
V
D
E
P
V
E
Site 4
T131
D
E
P
V
E
W
E
T
P
D
L
S
Q
A
E
Site 5
S135
E
W
E
T
P
D
L
S
Q
A
E
I
E
Q
K
Site 6
S157
I
N
S
N
L
F
M
S
L
N
K
D
G
S
Y
Site 7
S163
M
S
L
N
K
D
G
S
Y
T
G
F
I
K
V
Site 8
Y164
S
L
N
K
D
G
S
Y
T
G
F
I
K
V
Q
Site 9
S179
L
K
L
V
R
P
V
S
V
P
S
S
K
K
P
Site 10
S182
V
R
P
V
S
V
P
S
S
K
K
P
P
S
L
Site 11
S183
R
P
V
S
V
P
S
S
K
K
P
P
S
L
Q
Site 12
S188
P
S
S
K
K
P
P
S
L
Q
D
A
R
R
G
Site 13
T200
R
R
G
P
G
R
G
T
S
V
R
R
R
T
S
Site 14
S201
R
G
P
G
R
G
T
S
V
R
R
R
T
S
F
Site 15
T206
G
T
S
V
R
R
R
T
S
F
Y
L
P
K
D
Site 16
S207
T
S
V
R
R
R
T
S
F
Y
L
P
K
D
A
Site 17
Y209
V
R
R
R
T
S
F
Y
L
P
K
D
A
V
K
Site 18
S222
V
K
H
L
H
V
L
S
R
T
R
A
R
E
V
Site 19
T224
H
L
H
V
L
S
R
T
R
A
R
E
V
I
E
Site 20
Y259
A
E
R
H
G
Q
V
Y
L
R
K
L
L
D
D
Site 21
S284
G
P
S
D
K
A
L
S
F
V
L
K
E
N
D
Site 22
S292
F
V
L
K
E
N
D
S
G
E
V
N
W
D
A
Site 23
Y327
L
R
Q
I
L
Q
K
Y
S
Y
C
R
Q
K
I
Site 24
Y329
Q
I
L
Q
K
Y
S
Y
C
R
Q
K
I
Q
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation