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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RGS18
Full Name:
Regulator of G-protein signaling 18
Alias:
Type:
GTPase-activating protein for G protein
Mass (Da):
27582
Number AA:
235
UniProt ID:
Q9NS28
International Prot ID:
IPI00016825
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0009968
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
M
C
E
S
K
E
K
T
F
F
K
L
I
H
G
Site 2
S28
F
F
K
L
I
H
G
S
G
K
E
E
T
S
K
Site 3
S49
K
E
K
R
N
R
L
S
L
L
V
Q
K
P
E
Site 4
T61
K
P
E
F
H
E
D
T
R
S
S
R
S
G
H
Site 5
S63
E
F
H
E
D
T
R
S
S
R
S
G
H
L
A
Site 6
S64
F
H
E
D
T
R
S
S
R
S
G
H
L
A
K
Site 7
S76
L
A
K
E
T
R
V
S
P
E
E
A
V
K
W
Site 8
S86
E
A
V
K
W
G
E
S
F
D
K
L
L
S
H
Site 9
S92
E
S
F
D
K
L
L
S
H
R
D
G
L
E
A
Site 10
T106
A
F
T
R
F
L
K
T
E
F
S
E
E
N
I
Site 11
S109
R
F
L
K
T
E
F
S
E
E
N
I
E
F
W
Site 12
T145
I
Y
E
K
F
I
Q
T
D
A
P
K
E
V
N
Site 13
T157
E
V
N
L
D
F
H
T
K
E
V
I
T
N
S
Site 14
S164
T
K
E
V
I
T
N
S
I
T
Q
P
T
L
H
Site 15
S172
I
T
Q
P
T
L
H
S
F
D
A
A
Q
S
R
Site 16
Y181
D
A
A
Q
S
R
V
Y
Q
L
M
E
Q
D
S
Site 17
S188
Y
Q
L
M
E
Q
D
S
Y
T
R
F
L
K
S
Site 18
Y189
Q
L
M
E
Q
D
S
Y
T
R
F
L
K
S
D
Site 19
T190
L
M
E
Q
D
S
Y
T
R
F
L
K
S
D
I
Site 20
S195
S
Y
T
R
F
L
K
S
D
I
Y
L
D
L
M
Site 21
Y198
R
F
L
K
S
D
I
Y
L
D
L
M
E
G
R
Site 22
T210
E
G
R
P
Q
R
P
T
N
L
R
R
R
S
R
Site 23
S216
P
T
N
L
R
R
R
S
R
S
F
T
C
N
E
Site 24
S218
N
L
R
R
R
S
R
S
F
T
C
N
E
F
Q
Site 25
T220
R
R
R
S
R
S
F
T
C
N
E
F
Q
D
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation