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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADARB2
Full Name:
Double-stranded RNA-specific editase B2
Alias:
dsRNA adenosine deaminase B2
Type:
Mass (Da):
80603
Number AA:
739
UniProt ID:
Q9NS39
International Prot ID:
IPI00033017
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0003725
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006396
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
V
L
G
S
G
R
G
S
G
G
L
S
S
Q
L
Site 2
S15
G
R
G
S
G
G
L
S
S
Q
L
K
C
K
S
Site 3
S16
R
G
S
G
G
L
S
S
Q
L
K
C
K
S
K
Site 4
S22
S
S
Q
L
K
C
K
S
K
R
R
R
R
R
R
Site 5
S30
K
R
R
R
R
R
R
S
K
R
K
D
K
V
S
Site 6
S37
S
K
R
K
D
K
V
S
I
L
S
T
F
L
A
Site 7
T41
D
K
V
S
I
L
S
T
F
L
A
P
F
K
H
Site 8
S50
L
A
P
F
K
H
L
S
P
G
I
T
N
T
E
Site 9
T54
K
H
L
S
P
G
I
T
N
T
E
D
D
D
T
Site 10
T56
L
S
P
G
I
T
N
T
E
D
D
D
T
L
S
Site 11
T61
T
N
T
E
D
D
D
T
L
S
T
S
S
A
E
Site 12
S63
T
E
D
D
D
T
L
S
T
S
S
A
E
V
K
Site 13
S66
D
D
T
L
S
T
S
S
A
E
V
K
E
N
R
Site 14
S85
L
A
A
R
P
P
P
S
G
D
R
A
R
G
G
Site 15
S121
Q
L
V
W
K
K
L
S
W
S
V
A
P
K
N
Site 16
S123
V
W
K
K
L
S
W
S
V
A
P
K
N
A
L
Site 17
Y142
E
L
R
P
G
L
Q
Y
R
T
V
S
Q
T
G
Site 18
T144
R
P
G
L
Q
Y
R
T
V
S
Q
T
G
P
V
Site 19
S146
G
L
Q
Y
R
T
V
S
Q
T
G
P
V
H
A
Site 20
T148
Q
Y
R
T
V
S
Q
T
G
P
V
H
A
P
V
Site 21
T210
G
G
G
P
G
P
G
T
D
F
T
S
D
Q
A
Site 22
T213
P
G
P
G
T
D
F
T
S
D
Q
A
D
F
P
Site 23
T222
D
Q
A
D
F
P
D
T
L
F
Q
E
F
E
P
Site 24
S248
P
G
D
A
A
L
L
S
A
A
Y
G
R
R
R
Site 25
T270
L
V
G
P
T
P
A
T
P
A
A
P
G
E
R
Site 26
T316
A
V
S
V
D
G
R
T
F
E
G
S
G
R
S
Site 27
S320
D
G
R
T
F
E
G
S
G
R
S
K
K
L
A
Site 28
S323
T
F
E
G
S
G
R
S
K
K
L
A
R
G
Q
Site 29
T355
A
P
G
R
A
R
R
T
P
M
P
Q
E
F
A
Site 30
S364
M
P
Q
E
F
A
D
S
I
S
Q
L
V
T
Q
Site 31
S366
Q
E
F
A
D
S
I
S
Q
L
V
T
Q
K
F
Site 32
T370
D
S
I
S
Q
L
V
T
Q
K
F
R
E
V
T
Site 33
T377
T
Q
K
F
R
E
V
T
T
D
L
T
P
M
H
Site 34
T381
R
E
V
T
T
D
L
T
P
M
H
A
R
H
K
Site 35
S417
S
S
G
T
K
C
I
S
G
E
H
L
S
D
Q
Site 36
S454
T
Q
L
E
L
H
L
S
K
R
R
E
D
S
E
Site 37
S460
L
S
K
R
R
E
D
S
E
R
S
I
F
V
R
Site 38
S488
F
H
L
Y
V
S
T
S
P
C
G
D
A
R
L
Site 39
S497
C
G
D
A
R
L
H
S
P
Y
E
I
T
T
D
Site 40
Y499
D
A
R
L
H
S
P
Y
E
I
T
T
D
L
H
Site 41
T503
H
S
P
Y
E
I
T
T
D
L
H
S
S
K
H
Site 42
T521
K
F
R
G
H
L
R
T
K
I
E
S
G
E
G
Site 43
S525
H
L
R
T
K
I
E
S
G
E
G
T
V
P
V
Site 44
T529
K
I
E
S
G
E
G
T
V
P
V
R
G
P
S
Site 45
S536
T
V
P
V
R
G
P
S
A
V
Q
T
W
D
G
Site 46
T540
R
G
P
S
A
V
Q
T
W
D
G
V
L
L
G
Site 47
S554
G
E
Q
L
I
T
M
S
C
T
D
K
I
A
R
Site 48
S600
G
H
L
A
R
V
M
S
H
R
M
E
G
V
G
Site 49
S612
G
V
G
Q
L
P
A
S
Y
R
H
N
R
P
L
Site 50
Y613
V
G
Q
L
P
A
S
Y
R
H
N
R
P
L
L
Site 51
S621
R
H
N
R
P
L
L
S
G
V
S
D
A
E
A
Site 52
S624
R
P
L
L
S
G
V
S
D
A
E
A
R
Q
P
Site 53
S634
E
A
R
Q
P
G
K
S
P
P
F
S
M
N
W
Site 54
S638
P
G
K
S
P
P
F
S
M
N
W
V
V
G
S
Site 55
T655
L
E
I
I
N
A
T
T
G
R
R
S
C
G
G
Site 56
S659
N
A
T
T
G
R
R
S
C
G
G
P
S
R
L
Site 57
Y679
S
A
R
W
A
R
L
Y
G
R
L
S
T
R
T
Site 58
S683
A
R
L
Y
G
R
L
S
T
R
T
P
S
P
G
Site 59
T684
R
L
Y
G
R
L
S
T
R
T
P
S
P
G
D
Site 60
T686
Y
G
R
L
S
T
R
T
P
S
P
G
D
T
P
Site 61
S688
R
L
S
T
R
T
P
S
P
G
D
T
P
S
M
Site 62
T692
R
T
P
S
P
G
D
T
P
S
M
Y
C
E
A
Site 63
S694
P
S
P
G
D
T
P
S
M
Y
C
E
A
K
L
Site 64
Y696
P
G
D
T
P
S
M
Y
C
E
A
K
L
G
A
Site 65
Y706
A
K
L
G
A
H
T
Y
Q
S
V
K
Q
Q
L
Site 66
S708
L
G
A
H
T
Y
Q
S
V
K
Q
Q
L
F
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation