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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MBIP
Full Name:
MAP3K12-binding inhibitory protein 1
Alias:
MAP3K12 binding inhibitory protein 1; MAPK upstream kinase-binding inhibitory protein; MBIP1; MUK-binding inhibitory protein
Type:
Protein kinase, regulatory subunit
Mass (Da):
39281
Number AA:
344
UniProt ID:
Q9NS73
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0004860
PhosphoSite+
KinaseNET
Biological Process:
GO:0000173
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
A
T
E
L
N
R
P
S
S
G
D
R
N
L
E
Site 2
S12
T
E
L
N
R
P
S
S
G
D
R
N
L
E
R
Site 3
S26
R
R
C
R
P
N
L
S
R
E
V
L
Y
E
I
Site 4
Y31
N
L
S
R
E
V
L
Y
E
I
F
R
S
L
H
Site 5
S62
I
D
W
N
K
L
Q
S
L
S
A
F
Q
P
A
Site 6
S91
P
F
L
A
K
L
Q
S
P
I
K
E
E
N
T
Site 7
T99
P
I
K
E
E
N
T
T
A
V
E
E
I
G
R
Site 8
T107
A
V
E
E
I
G
R
T
E
M
G
N
K
N
E
Site 9
T141
D
L
R
D
V
K
K
T
Q
I
H
F
D
P
E
Site 10
S164
A
E
I
D
R
R
I
S
A
F
I
E
R
K
Q
Site 11
T197
Q
E
N
S
C
A
R
T
D
A
I
F
T
P
Y
Site 12
T202
A
R
T
D
A
I
F
T
P
Y
P
G
F
K
S
Site 13
Y204
T
D
A
I
F
T
P
Y
P
G
F
K
S
H
V
Site 14
S209
T
P
Y
P
G
F
K
S
H
V
K
V
S
R
V
Site 15
Y220
V
S
R
V
V
N
T
Y
G
P
Q
T
R
P
E
Site 16
S232
R
P
E
G
I
P
G
S
G
H
K
P
N
S
M
Site 17
S238
G
S
G
H
K
P
N
S
M
L
R
D
C
G
N
Site 18
T263
E
A
H
L
R
L
Q
T
G
G
P
V
P
R
D
Site 19
Y272
G
P
V
P
R
D
I
Y
Q
R
I
K
K
L
E
Site 20
Y292
L
E
G
I
S
P
E
Y
F
Q
S
V
S
F
S
Site 21
S295
I
S
P
E
Y
F
Q
S
V
S
F
S
G
K
R
Site 22
S297
P
E
Y
F
Q
S
V
S
F
S
G
K
R
R
K
Site 23
S299
Y
F
Q
S
V
S
F
S
G
K
R
R
K
V
Q
Site 24
S313
Q
P
P
Q
Q
N
Y
S
L
A
E
L
D
E
K
Site 25
S332
K
Q
A
L
L
R
K
S
R
E
A
E
S
M
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation