PhosphoNET

           
Protein Info 
   
Short Name:  FGF21
Full Name:  Fibroblast growth factor 21
Alias: 
Type: 
Mass (Da):  22300
Number AA:  209
UniProt ID:  Q9NSA1
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S34QAHPIPDSSPLLQFG
Site 2S35AHPIPDSSPLLQFGG
Site 3Y48GGQVRQRYLYTDDAQ
Site 4Y50QVRQRYLYTDDAQQT
Site 5T57YTDDAQQTEAHLEIR
Site 6T68LEIREDGTVGGAADQ
Site 7S76VGGAADQSPESLLQL
Site 8S79AADQSPESLLQLKAL
Site 9S99QILGVKTSRFLCQRP
Site 10Y111QRPDGALYGSLHFDP
Site 11S113PDGALYGSLHFDPEA
Site 12S122HFDPEACSFRELLLE
Site 13Y132ELLLEDGYNVYQSEA
Site 14Y135LEDGYNVYQSEAHGL
Site 15S137DGYNVYQSEAHGLPL
Site 16S151LHLPGNKSPHRDPAP
Site 17S190PQPPDVGSSDPLSMV
Site 18S191QPPDVGSSDPLSMVG
Site 19S195VGSSDPLSMVGPSQG
Site 20S200PLSMVGPSQGRSPSY
Site 21S204VGPSQGRSPSYAS__
Site 22S206PSQGRSPSYAS____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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