KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KCND1
Full Name:
Potassium voltage-gated channel subfamily D member 1
Alias:
KV4.1; Potassium voltage-gated channel, Shal-related subfamily, member 1; Voltage-gated potassium channel Kv4.1
Type:
Membrane, Voltage-gated potassium channel complex, Integral membrane protein
Mass (Da):
71330
Number AA:
647
UniProt ID:
Q9NSA2
International Prot ID:
IPI00007507
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0008076
Uniprot
OncoNet
Molecular Function:
GO:0030955
GO:0005515
GO:0005249
PhosphoSite+
KinaseNET
Biological Process:
GO:0006813
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S47
E
V
L
V
V
N
V
S
G
R
R
F
E
T
W
Site 2
T53
V
S
G
R
R
F
E
T
W
K
N
T
L
D
R
Site 3
Y61
W
K
N
T
L
D
R
Y
P
D
T
L
L
G
S
Site 4
T64
T
L
D
R
Y
P
D
T
L
L
G
S
S
E
K
Site 5
S68
Y
P
D
T
L
L
G
S
S
E
K
E
F
F
Y
Site 6
Y75
S
S
E
K
E
F
F
Y
D
A
D
S
G
E
Y
Site 7
Y82
Y
D
A
D
S
G
E
Y
F
F
D
R
D
P
D
Site 8
Y98
F
R
H
V
L
N
F
Y
R
T
G
R
L
H
C
Site 9
T100
H
V
L
N
F
Y
R
T
G
R
L
H
C
P
R
Site 10
S167
P
A
L
P
A
G
S
S
L
R
Q
R
L
W
R
Site 11
T181
R
A
F
E
N
P
H
T
S
T
A
A
L
V
F
Site 12
S213
E
T
I
P
C
R
G
S
A
R
R
S
S
R
E
Site 13
S217
C
R
G
S
A
R
R
S
S
R
E
Q
P
C
G
Site 14
S218
R
G
S
A
R
R
S
S
R
E
Q
P
C
G
E
Site 15
S255
L
R
L
F
A
A
P
S
R
C
R
F
L
R
S
Site 16
S288
V
P
K
N
D
D
V
S
G
A
F
V
T
L
R
Site 17
S306
V
F
R
I
F
K
F
S
R
H
S
Q
G
L
R
Site 18
S309
I
F
K
F
S
R
H
S
Q
G
L
R
I
L
G
Site 19
Y317
Q
G
L
R
I
L
G
Y
T
L
K
S
C
A
S
Site 20
T318
G
L
R
I
L
G
Y
T
L
K
S
C
A
S
E
Site 21
T354
A
E
K
G
T
N
K
T
N
F
T
S
I
P
A
Site 22
Y415
V
S
N
F
S
R
I
Y
H
Q
N
Q
R
A
D
Site 23
S440
A
R
I
R
L
A
K
S
G
T
T
N
A
F
L
Site 24
T442
I
R
L
A
K
S
G
T
T
N
A
F
L
Q
Y
Site 25
Y449
T
T
N
A
F
L
Q
Y
K
Q
N
G
G
L
E
Site 26
S458
Q
N
G
G
L
E
D
S
G
S
G
E
E
Q
A
Site 27
S460
G
G
L
E
D
S
G
S
G
E
E
Q
A
L
C
Site 28
S472
A
L
C
V
R
N
R
S
A
F
E
Q
Q
H
H
Site 29
T488
L
L
H
C
L
E
K
T
T
C
H
E
F
T
D
Site 30
T498
H
E
F
T
D
E
L
T
F
S
E
A
L
G
A
Site 31
S507
S
E
A
L
G
A
V
S
P
G
G
R
T
S
R
Site 32
S513
V
S
P
G
G
R
T
S
R
S
T
S
V
S
S
Site 33
S515
P
G
G
R
T
S
R
S
T
S
V
S
S
Q
P
Site 34
T516
G
G
R
T
S
R
S
T
S
V
S
S
Q
P
V
Site 35
S517
G
R
T
S
R
S
T
S
V
S
S
Q
P
V
G
Site 36
S519
T
S
R
S
T
S
V
S
S
Q
P
V
G
P
G
Site 37
S520
S
R
S
T
S
V
S
S
Q
P
V
G
P
G
S
Site 38
S531
G
P
G
S
L
L
S
S
C
C
P
R
R
A
K
Site 39
S547
R
A
I
R
L
A
N
S
T
A
S
V
S
R
G
Site 40
T548
A
I
R
L
A
N
S
T
A
S
V
S
R
G
S
Site 41
S550
R
L
A
N
S
T
A
S
V
S
R
G
S
M
Q
Site 42
S555
T
A
S
V
S
R
G
S
M
Q
E
L
D
M
L
Site 43
S568
M
L
A
G
L
R
R
S
H
A
P
Q
S
R
S
Site 44
S573
R
R
S
H
A
P
Q
S
R
S
S
L
N
A
K
Site 45
S575
S
H
A
P
Q
S
R
S
S
L
N
A
K
P
H
Site 46
S576
H
A
P
Q
S
R
S
S
L
N
A
K
P
H
D
Site 47
S584
L
N
A
K
P
H
D
S
L
D
L
N
C
D
S
Site 48
T603
A
A
I
I
S
I
P
T
P
P
A
N
T
P
D
Site 49
T608
I
P
T
P
P
A
N
T
P
D
E
S
Q
P
S
Site 50
S612
P
A
N
T
P
D
E
S
Q
P
S
S
P
G
G
Site 51
S615
T
P
D
E
S
Q
P
S
S
P
G
G
G
G
R
Site 52
S616
P
D
E
S
Q
P
S
S
P
G
G
G
G
R
A
Site 53
S625
G
G
G
G
R
A
G
S
T
L
R
N
S
S
L
Site 54
T626
G
G
G
R
A
G
S
T
L
R
N
S
S
L
G
Site 55
S630
A
G
S
T
L
R
N
S
S
L
G
T
P
C
L
Site 56
S631
G
S
T
L
R
N
S
S
L
G
T
P
C
L
F
Site 57
T634
L
R
N
S
S
L
G
T
P
C
L
F
P
E
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation