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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SAMSN1
Full Name:
SAM domain-containing protein SAMSN-1
Alias:
NASH1; nuclear localization signals, SAM and SH3 domain containing 1; SAM and SH3 domain containing 2; SAM domain, SH3 domain and nuclear localisation signals protein 1; SAM domain, SH3 domain and nuclear localization signals 1; SAM-domain protein SAMSN-1; SAMN1; SASH2; SH3D6B; SSN1
Type:
Adapter/scaffold protein
Mass (Da):
41708
Number AA:
373
UniProt ID:
Q9NSI8
International Prot ID:
IPI00339277
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0001784
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
L
K
R
K
P
S
N
V
S
E
K
E
K
Site 2
S21
K
H
Q
K
P
K
R
S
S
S
F
G
N
F
D
Site 3
S22
H
Q
K
P
K
R
S
S
S
F
G
N
F
D
R
Site 4
S23
Q
K
P
K
R
S
S
S
F
G
N
F
D
R
F
Site 5
S34
F
D
R
F
R
N
N
S
L
S
K
P
D
D
S
Site 6
S36
R
F
R
N
N
S
L
S
K
P
D
D
S
T
E
Site 7
S41
S
L
S
K
P
D
D
S
T
E
A
H
E
G
D
Site 8
T42
L
S
K
P
D
D
S
T
E
A
H
E
G
D
P
Site 9
T50
E
A
H
E
G
D
P
T
N
G
S
G
E
Q
S
Site 10
S53
E
G
D
P
T
N
G
S
G
E
Q
S
K
T
S
Site 11
S57
T
N
G
S
G
E
Q
S
K
T
S
N
N
G
G
Site 12
T59
G
S
G
E
Q
S
K
T
S
N
N
G
G
G
L
Site 13
S60
S
G
E
Q
S
K
T
S
N
N
G
G
G
L
G
Site 14
S74
G
K
K
M
R
A
I
S
W
T
M
K
K
K
V
Site 15
T76
K
M
R
A
I
S
W
T
M
K
K
K
V
G
K
Site 16
Y85
K
K
K
V
G
K
K
Y
I
K
A
L
S
E
E
Site 17
S90
K
K
Y
I
K
A
L
S
E
E
K
D
E
E
D
Site 18
Y104
D
G
E
N
A
H
P
Y
R
N
S
D
P
V
I
Site 19
S107
N
A
H
P
Y
R
N
S
D
P
V
I
G
T
H
Site 20
T115
D
P
V
I
G
T
H
T
E
K
V
S
L
K
A
Site 21
S119
G
T
H
T
E
K
V
S
L
K
A
S
D
S
M
Site 22
S123
E
K
V
S
L
K
A
S
D
S
M
D
S
L
Y
Site 23
S125
V
S
L
K
A
S
D
S
M
D
S
L
Y
S
G
Site 24
S128
K
A
S
D
S
M
D
S
L
Y
S
G
Q
S
S
Site 25
Y130
S
D
S
M
D
S
L
Y
S
G
Q
S
S
S
S
Site 26
S131
D
S
M
D
S
L
Y
S
G
Q
S
S
S
S
G
Site 27
S134
D
S
L
Y
S
G
Q
S
S
S
S
G
I
T
S
Site 28
S135
S
L
Y
S
G
Q
S
S
S
S
G
I
T
S
C
Site 29
S136
L
Y
S
G
Q
S
S
S
S
G
I
T
S
C
S
Site 30
S137
Y
S
G
Q
S
S
S
S
G
I
T
S
C
S
D
Site 31
T140
Q
S
S
S
S
G
I
T
S
C
S
D
G
T
S
Site 32
S141
S
S
S
S
G
I
T
S
C
S
D
G
T
S
N
Site 33
S143
S
S
G
I
T
S
C
S
D
G
T
S
N
R
D
Site 34
S147
T
S
C
S
D
G
T
S
N
R
D
S
F
R
L
Site 35
S151
D
G
T
S
N
R
D
S
F
R
L
D
D
D
G
Site 36
Y160
R
L
D
D
D
G
P
Y
S
G
P
F
C
G
R
Site 37
S161
L
D
D
D
G
P
Y
S
G
P
F
C
G
R
A
Site 38
T172
C
G
R
A
R
V
H
T
D
F
T
P
S
P
Y
Site 39
T175
A
R
V
H
T
D
F
T
P
S
P
Y
D
T
D
Site 40
S177
V
H
T
D
F
T
P
S
P
Y
D
T
D
S
L
Site 41
Y179
T
D
F
T
P
S
P
Y
D
T
D
S
L
K
I
Site 42
T181
F
T
P
S
P
Y
D
T
D
S
L
K
I
K
K
Site 43
S183
P
S
P
Y
D
T
D
S
L
K
I
K
K
G
D
Site 44
S238
K
I
K
A
N
R
R
S
N
S
K
K
S
K
T
Site 45
S240
K
A
N
R
R
S
N
S
K
K
S
K
T
L
Q
Site 46
T245
S
N
S
K
K
S
K
T
L
Q
E
F
L
E
R
Site 47
Y258
E
R
I
H
L
Q
E
Y
T
S
T
L
L
L
N
Site 48
S260
I
H
L
Q
E
Y
T
S
T
L
L
L
N
G
Y
Site 49
T261
H
L
Q
E
Y
T
S
T
L
L
L
N
G
Y
E
Site 50
Y267
S
T
L
L
L
N
G
Y
E
T
L
E
D
L
K
Site 51
S297
D
D
R
R
R
L
L
S
A
A
E
N
F
L
E
Site 52
S319
E
N
E
P
E
P
L
S
L
S
S
D
I
S
L
Site 53
S321
E
P
E
P
L
S
L
S
S
D
I
S
L
N
K
Site 54
S322
P
E
P
L
S
L
S
S
D
I
S
L
N
K
S
Site 55
S325
L
S
L
S
S
D
I
S
L
N
K
S
Q
L
D
Site 56
S329
S
D
I
S
L
N
K
S
Q
L
D
D
C
P
R
Site 57
S338
L
D
D
C
P
R
D
S
G
C
Y
I
S
S
G
Site 58
Y341
C
P
R
D
S
G
C
Y
I
S
S
G
N
S
D
Site 59
S343
R
D
S
G
C
Y
I
S
S
G
N
S
D
N
G
Site 60
S344
D
S
G
C
Y
I
S
S
G
N
S
D
N
G
K
Site 61
S347
C
Y
I
S
S
G
N
S
D
N
G
K
E
D
L
Site 62
S356
N
G
K
E
D
L
E
S
E
N
L
S
D
M
V
Site 63
S360
D
L
E
S
E
N
L
S
D
M
V
H
K
I
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation