PhosphoNET

           
Protein Info 
   
Short Name:  MAN2C1
Full Name:  Alpha-mannosidase 2C1
Alias:  Alpha mannosidase 6A8B;Alpha-D-mannoside mannohydrolase;Mannosidase alpha class 2C member 1
Type: 
Mass (Da):  115835
Number AA:  1040
UniProt ID:  Q9NTJ4
International Prot ID:  IPI00783434
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0004559  GO:0005515  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0006013     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T13ALKHWRTTLERVEKF
Site 2S22ERVEKFVSPLYFTDC
Site 3Y25EKFVSPLYFTDCNLR
Site 4T50AVLSSFLTPERLPYQ
Site 5Y56LTPERLPYQEAVQRD
Site 6S72RPAQVGDSFGPTWWT
Site 7T126LTKEGEKTSYVLTDR
Site 8Y128KEGEKTSYVLTDRLG
Site 9T131EKTSYVLTDRLGERD
Site 10S141LGERDPRSLTLYVEV
Site 11T143ERDPRSLTLYVEVAC
Site 12Y145DPRSLTLYVEVACNG
Site 13S209LGKDNQRSFQALYTA
Site 14Y214QRSFQALYTANQMVN
Site 15T230CDPAQPETFPVAQAL
Site 16S239PVAQALASRFFGQHG
Site 17T252HGGESQHTIHATGHC
Site 18S279TVRKCARSWVTALQL
Site 19S308QQLEWVKSRYPGLYS
Site 20Y310LEWVKSRYPGLYSRI
Site 21Y314KSRYPGLYSRIQEFA
Site 22S342EMDGNLPSGEAMVRQ
Site 23T373SEFWLPDTFGYSAQL
Site 24T394CGIRRFLTQKLSWNL
Site 25S398RFLTQKLSWNLVNSF
Site 26S429VHFPPGDSYGMQGSV
Site 27Y430HFPPGDSYGMQGSVE
Site 28S435DSYGMQGSVEEVLKT
Site 29T442SVEEVLKTVANNRDK
Site 30S455DKGRANHSAFLFGFG
Site 31T471GGGGPTQTMLDRLKR
Site 32S480LDRLKRLSNTDGLPR
Site 33T482RLKRLSNTDGLPRVQ
Site 34S491GLPRVQLSSPRQLFS
Site 35S492LPRVQLSSPRQLFSA
Site 36S498SSPRQLFSALESDSE
Site 37S502QLFSALESDSEQLCT
Site 38S504FSALESDSEQLCTWV
Site 39Y559ARSAQFLYPAAQLQH
Site 40Y596AEEAMCHYEDIRSHG
Site 41T605DIRSHGNTLLSAAAA
Site 42S667APVPPPTSLQPLLPQ
Site 43S686VVQETDGSVTLDNGI
Site 44T701IRVKLDPTGRLTSLV
Site 45S712TSLVLVASGREAIAE
Site 46Y744DAWDVMDYHLETRKP
Site 47T748VMDYHLETRKPVLGQ
Site 48S778AWFLLQISPNSRLSQ
Site 49S784ISPNSRLSQEVVLDV
Site 50S821EFPARVRSSQATYEI
Site 51S822FPARVRSSQATYEIQ
Site 52T825RVRSSQATYEIQFGH
Site 53Y826VRSSQATYEIQFGHL
Site 54S859AHRWMDLSEHGFGLA
Site 55Y873ALLNDCKYGASVRGS
Site 56S876NDCKYGASVRGSILS
Site 57T896APKAPDATADTGRHE
Site 58T899APDATADTGRHEFTY
Site 59T905DTGRHEFTYALMPHK
Site 60Y906TGRHEFTYALMPHKG
Site 61S944PSPAPATSWSAFSVS
Site 62S946PAPATSWSAFSVSSP
Site 63T959SPAVVLETVKQAESS
Site 64S966TVKQAESSPQRRSLV
Site 65S971ESSPQRRSLVLRLYE
Site 66Y977RSLVLRLYEAHGSHV
Site 67T1013PDPAGHLTLRDNRLK
Site 68T1022RDNRLKLTFSPFQVL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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