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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZBTB40
Full Name:
Zinc finger and BTB domain-containing protein 40
Alias:
KIAA0478; Y478; ZBT40; Zinc finger and BTB domain containing 40; Zinc finger protein KIAA0478
Type:
Mass (Da):
138118
Number AA:
1239
UniProt ID:
Q9NUA8
International Prot ID:
IPI00332552
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
R
Q
L
L
Q
Q
L
Y
T
L
C
K
E
Q
Q
Site 2
T16
Q
L
L
Q
Q
L
Y
T
L
C
K
E
Q
Q
F
Site 3
S91
P
V
G
K
H
N
F
S
K
I
I
S
L
A
D
Site 4
S130
G
Q
V
V
R
D
V
S
A
P
S
S
E
T
F
Site 5
S134
R
D
V
S
A
P
S
S
E
T
F
R
K
E
P
Site 6
T136
V
S
A
P
S
S
E
T
F
R
K
E
P
E
K
Site 7
S151
P
Q
V
E
I
L
S
S
E
G
A
G
E
P
H
Site 8
S159
E
G
A
G
E
P
H
S
S
P
E
L
A
A
T
Site 9
S160
G
A
G
E
P
H
S
S
P
E
L
A
A
T
P
Site 10
T166
S
S
P
E
L
A
A
T
P
G
G
P
V
K
A
Site 11
S181
E
T
E
E
A
A
H
S
V
S
Q
E
M
S
V
Site 12
S183
E
E
A
A
H
S
V
S
Q
E
M
S
V
N
S
Site 13
S187
H
S
V
S
Q
E
M
S
V
N
S
P
T
A
Q
Site 14
S190
S
Q
E
M
S
V
N
S
P
T
A
Q
E
S
Q
Site 15
S196
N
S
P
T
A
Q
E
S
Q
R
N
A
E
T
P
Site 16
T202
E
S
Q
R
N
A
E
T
P
A
E
T
P
T
T
Site 17
T206
N
A
E
T
P
A
E
T
P
T
T
A
E
A
C
Site 18
T209
T
P
A
E
T
P
T
T
A
E
A
C
S
P
S
Site 19
S214
P
T
T
A
E
A
C
S
P
S
P
A
V
Q
T
Site 20
S216
T
A
E
A
C
S
P
S
P
A
V
Q
T
F
S
Site 21
T221
S
P
S
P
A
V
Q
T
F
S
E
A
K
K
T
Site 22
S223
S
P
A
V
Q
T
F
S
E
A
K
K
T
S
T
Site 23
T228
T
F
S
E
A
K
K
T
S
T
E
P
G
C
E
Site 24
S229
F
S
E
A
K
K
T
S
T
E
P
G
C
E
R
Site 25
T230
S
E
A
K
K
T
S
T
E
P
G
C
E
R
K
Site 26
Y239
P
G
C
E
R
K
H
Y
Q
L
N
F
L
L
E
Site 27
S269
L
K
K
L
E
M
C
S
E
I
K
G
P
Q
K
Site 28
S290
F
E
G
E
G
G
H
S
A
F
Q
R
I
L
G
Site 29
S303
L
G
K
V
R
E
E
S
L
D
V
Q
T
V
V
Site 30
Y318
S
L
L
R
L
Y
Q
Y
S
N
P
A
V
K
T
Site 31
S319
L
L
R
L
Y
Q
Y
S
N
P
A
V
K
T
A
Site 32
T337
R
K
P
E
D
V
D
T
V
Q
P
K
G
S
T
Site 33
T349
G
S
T
E
E
G
K
T
L
S
V
L
L
L
E
Site 34
S351
T
E
E
G
K
T
L
S
V
L
L
L
E
H
K
Site 35
S374
Q
L
R
P
I
M
E
S
L
E
T
A
K
E
E
Site 36
T377
P
I
M
E
S
L
E
T
A
K
E
E
F
L
T
Site 37
T384
T
A
K
E
E
F
L
T
G
T
E
K
R
V
I
Site 38
T399
L
N
C
C
E
G
R
T
P
K
E
T
I
E
N
Site 39
T403
E
G
R
T
P
K
E
T
I
E
N
L
L
H
R
Site 40
T412
E
N
L
L
H
R
M
T
E
E
K
T
L
T
A
Site 41
T416
H
R
M
T
E
E
K
T
L
T
A
E
G
L
V
Site 42
T418
M
T
E
E
K
T
L
T
A
E
G
L
V
K
L
Site 43
S446
L
L
E
K
L
Q
K
S
A
T
L
P
S
T
T
Site 44
T448
E
K
L
Q
K
S
A
T
L
P
S
T
T
V
Q
Site 45
S451
Q
K
S
A
T
L
P
S
T
T
V
Q
P
S
P
Site 46
T452
K
S
A
T
L
P
S
T
T
V
Q
P
S
P
D
Site 47
T453
S
A
T
L
P
S
T
T
V
Q
P
S
P
D
D
Site 48
S457
P
S
T
T
V
Q
P
S
P
D
D
Y
G
T
E
Site 49
Y461
V
Q
P
S
P
D
D
Y
G
T
E
L
L
R
R
Site 50
T463
P
S
P
D
D
Y
G
T
E
L
L
R
R
Y
H
Site 51
Y469
G
T
E
L
L
R
R
Y
H
E
N
L
S
E
I
Site 52
S474
R
R
Y
H
E
N
L
S
E
I
F
T
D
N
Q
Site 53
T478
E
N
L
S
E
I
F
T
D
N
Q
I
L
L
K
Site 54
S492
K
M
I
S
H
M
T
S
L
A
P
G
E
R
E
Site 55
S509
E
K
L
V
K
R
D
S
G
S
G
G
F
N
S
Site 56
S511
L
V
K
R
D
S
G
S
G
G
F
N
S
L
I
Site 57
S600
I
E
Y
K
L
F
T
S
E
E
E
H
L
A
E
Site 58
T608
E
E
E
H
L
A
E
T
V
K
E
I
L
S
I
Site 59
S614
E
T
V
K
E
I
L
S
I
P
S
E
T
A
S
Site 60
S617
K
E
I
L
S
I
P
S
E
T
A
S
P
E
A
Site 61
S621
S
I
P
S
E
T
A
S
P
E
A
S
L
R
A
Site 62
S625
E
T
A
S
P
E
A
S
L
R
A
V
L
S
R
Site 63
S703
E
K
A
A
K
E
D
S
Q
P
G
E
Q
N
D
Site 64
S716
N
D
Q
G
E
T
G
S
L
P
G
Q
Q
E
K
Site 65
S726
G
Q
Q
E
K
E
A
S
A
S
P
D
P
A
K
Site 66
S728
Q
E
K
E
A
S
A
S
P
D
P
A
K
K
S
Site 67
S735
S
P
D
P
A
K
K
S
F
I
C
K
A
C
D
Site 68
S763
K
R
C
R
V
A
K
S
K
Q
V
Q
C
K
E
Site 69
S772
Q
V
Q
C
K
E
C
S
E
T
K
D
S
K
K
Site 70
T774
Q
C
K
E
C
S
E
T
K
D
S
K
K
E
L
Site 71
S777
E
C
S
E
T
K
D
S
K
K
E
L
D
K
H
Site 72
T808
K
K
K
R
L
P
V
T
C
D
L
C
G
R
E
Site 73
S820
G
R
E
F
A
H
A
S
G
M
Q
Y
H
K
L
Site 74
Y824
A
H
A
S
G
M
Q
Y
H
K
L
T
E
H
F
Site 75
S837
H
F
D
E
K
P
F
S
C
E
E
C
G
A
K
Site 76
T859
K
N
H
L
R
L
H
T
G
D
R
P
F
M
C
Site 77
Y881
T
Q
A
S
A
L
A
Y
H
T
K
K
K
H
S
Site 78
Y893
K
H
S
E
G
K
M
Y
A
C
Q
Y
C
D
A
Site 79
Y897
G
K
M
Y
A
C
Q
Y
C
D
A
V
F
A
Q
Site 80
S909
F
A
Q
S
I
E
L
S
R
H
V
R
T
H
T
Site 81
T916
S
R
H
V
R
T
H
T
G
D
K
P
Y
V
C
Site 82
Y921
T
H
T
G
D
K
P
Y
V
C
R
D
C
G
K
Site 83
T942
G
L
S
I
H
L
H
T
F
H
N
I
E
D
P
Site 84
Y950
F
H
N
I
E
D
P
Y
D
C
K
K
C
R
M
Site 85
T961
K
C
R
M
S
F
P
T
L
Q
D
H
R
K
H
Site 86
S988
P
T
C
G
K
I
F
S
A
P
S
M
L
E
R
Site 87
Y1015
C
G
I
C
N
K
A
Y
Q
Q
L
S
G
L
W
Site 88
Y1023
Q
Q
L
S
G
L
W
Y
H
N
R
T
H
H
P
Site 89
S1040
F
A
A
Q
N
H
R
S
S
K
F
S
S
L
Q
Site 90
S1041
A
A
Q
N
H
R
S
S
K
F
S
S
L
Q
C
Site 91
S1044
N
H
R
S
S
K
F
S
S
L
Q
C
S
S
C
Site 92
S1045
H
R
S
S
K
F
S
S
L
Q
C
S
S
C
D
Site 93
S1049
K
F
S
S
L
Q
C
S
S
C
D
K
T
F
P
Site 94
S1050
F
S
S
L
Q
C
S
S
C
D
K
T
F
P
N
Site 95
T1124
G
A
L
Q
H
H
V
T
T
E
H
F
K
Q
S
Site 96
T1134
H
F
K
Q
S
E
T
T
F
P
C
E
L
C
G
Site 97
S1146
L
C
G
E
L
F
T
S
Q
A
Q
L
D
S
H
Site 98
S1152
T
S
Q
A
Q
L
D
S
H
L
E
S
E
H
P
Site 99
S1156
Q
L
D
S
H
L
E
S
E
H
P
K
V
M
S
Site 100
S1163
S
E
H
P
K
V
M
S
T
E
T
Q
A
A
A
Site 101
T1164
E
H
P
K
V
M
S
T
E
T
Q
A
A
A
S
Site 102
T1179
Q
M
A
Q
V
I
Q
T
P
E
P
V
A
P
T
Site 103
T1191
A
P
T
E
Q
V
I
T
L
E
E
T
Q
L
A
Site 104
S1209
V
F
V
T
L
P
D
S
Q
A
S
Q
A
S
S
Site 105
S1212
T
L
P
D
S
Q
A
S
Q
A
S
S
E
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation