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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZDHHC18
Full Name:
Palmitoyltransferase ZDHHC18
Alias:
DHHC-18; EC 2.3.1.-; ZDH18; Zinc finger DHHC domain-containing 18
Type:
Transferase
Mass (Da):
42031
Number AA:
388
UniProt ID:
Q9NUE0
International Prot ID:
IPI00183979
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0008415
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
K
D
C
E
Y
Q
Q
I
S
P
G
A
Site 2
S10
D
C
E
Y
Q
Q
I
S
P
G
A
A
P
L
P
Site 3
S19
G
A
A
P
L
P
A
S
P
G
A
R
R
P
G
Site 4
S30
R
R
P
G
P
A
A
S
P
T
P
G
P
G
P
Site 5
T32
P
G
P
A
A
S
P
T
P
G
P
G
P
A
P
Site 6
S49
A
P
A
P
P
R
W
S
S
S
G
S
G
S
G
Site 7
S50
P
A
P
P
R
W
S
S
S
G
S
G
S
G
S
Site 8
S51
A
P
P
R
W
S
S
S
G
S
G
S
G
S
G
Site 9
S53
P
R
W
S
S
S
G
S
G
S
G
S
G
S
G
Site 10
S55
W
S
S
S
G
S
G
S
G
S
G
S
G
S
L
Site 11
S57
S
S
G
S
G
S
G
S
G
S
G
S
L
G
R
Site 12
S59
G
S
G
S
G
S
G
S
G
S
L
G
R
R
P
Site 13
S61
G
S
G
S
G
S
G
S
L
G
R
R
P
R
R
Site 14
Y80
F
P
G
R
N
R
F
Y
C
G
G
R
L
M
L
Site 15
T168
L
E
K
Q
I
D
N
T
G
S
S
T
Y
R
P
Site 16
S170
K
Q
I
D
N
T
G
S
S
T
Y
R
P
P
P
Site 17
S171
Q
I
D
N
T
G
S
S
T
Y
R
P
P
P
R
Site 18
T172
I
D
N
T
G
S
S
T
Y
R
P
P
P
R
T
Site 19
Y173
D
N
T
G
S
S
T
Y
R
P
P
P
R
T
R
Site 20
T179
T
Y
R
P
P
P
R
T
R
E
V
L
I
N
G
Site 21
Y238
R
R
N
Y
R
F
F
Y
A
F
I
L
S
L
S
Site 22
S266
L
T
L
R
A
Q
G
S
N
F
L
S
T
L
K
Site 23
S270
A
Q
G
S
N
F
L
S
T
L
K
E
T
P
A
Site 24
T271
Q
G
S
N
F
L
S
T
L
K
E
T
P
A
S
Site 25
T309
L
V
A
S
N
L
T
T
N
E
D
I
K
G
S
Site 26
S316
T
N
E
D
I
K
G
S
W
S
S
K
R
G
G
Site 27
S318
E
D
I
K
G
S
W
S
S
K
R
G
G
E
A
Site 28
S319
D
I
K
G
S
W
S
S
K
R
G
G
E
A
S
Site 29
S326
S
K
R
G
G
E
A
S
V
N
P
Y
S
H
K
Site 30
Y330
G
E
A
S
V
N
P
Y
S
H
K
S
I
I
T
Site 31
S331
E
A
S
V
N
P
Y
S
H
K
S
I
I
T
N
Site 32
S360
D
R
R
G
F
V
Q
S
D
T
V
L
P
S
P
Site 33
T362
R
G
F
V
Q
S
D
T
V
L
P
S
P
I
R
Site 34
S366
Q
S
D
T
V
L
P
S
P
I
R
S
D
E
P
Site 35
S370
V
L
P
S
P
I
R
S
D
E
P
A
C
R
A
Site 36
S382
C
R
A
K
P
D
A
S
M
V
G
G
H
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation